The role of maternal anxiety disorder subtype, parenting, and infant stable temperamental inhibition in child anxiety: a prospective longitudinal study
The role of maternal anxiety disorder subtype, parenting, and infant stable temperamental inhibition in child anxiety: a prospective longitudinal study
Background:
Social Anxiety Disorder (SAD) aggregates in families. To elucidate intergenerational transmission of risk, we examined whether childhood SAD and symptoms of anxiety were prospectively predicted by stable infant temperamental inhibition, maternal SAD, maternal Generalized Anxiety Disorder (GAD), and maternal parenting behaviours.
Methods:
We conducted a longitudinal study beginning prenatally with follow-up at 4-, 10-, 14- and 58-months postnatally. Mothers were assessed for anxiety disorders prenatally and assigned to one of three groups: SAD (n=67), GAD (n=56), and non-anxious controls (n=94). We assessed infant temperamental inhibition at 4- and 14-months, maternal parenting behaviours at 10- and 58-months, and child anxiety disorders and symptoms at 58-months.
Results:
Child SAD at 58-months was predicted by prenatal maternal SAD (OR=23.76, 95%CI=1.15-60.37), but not by prenatal maternal GAD (OR = 7.44, 95% CI = 0.32-124.49), stable temperamental inhibition, or maternal behaviours. Child anxiety symptoms at 58-months were predicted specifically by maternal SAD (but not GAD), and also by concurrent maternal intrusiveness. Stable temperamental inhibition moderated the association between 10-month maternal encouragement and 58-month child anxiety symptoms.
Conclusions:
We found evidence for specificity of risk for child SAD and anxiety symptoms from maternal SAD compared to maternal GAD. Childhood anxiety symptoms were also predicted by an interaction between a lack of maternal encouragement in infancy and stable temperamental inhibition, as well as concurrent maternal intrusiveness. The findings have clinical implications for targeted prevention of child anxiety.
Anxiety, high risk studies, prevention, temperament
779-788
Lawrence, Peter
0d45e107-38ef-4932-aec1-504573de01ef
Creswell, Cathy
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Cooper, Peter J.
97cbf18b-3033-47c8-8ab3-f7439638fb3c
Murray, Lynne
895182cd-2579-40e6-9fbb-615447c3a490
1 July 2020
Lawrence, Peter
0d45e107-38ef-4932-aec1-504573de01ef
Creswell, Cathy
a4dc4d1f-007d-48b5-9ddf-2d24da87b489
Cooper, Peter J.
97cbf18b-3033-47c8-8ab3-f7439638fb3c
Murray, Lynne
895182cd-2579-40e6-9fbb-615447c3a490
Lawrence, Peter, Creswell, Cathy, Cooper, Peter J. and Murray, Lynne
(2020)
The role of maternal anxiety disorder subtype, parenting, and infant stable temperamental inhibition in child anxiety: a prospective longitudinal study.
Journal of Child Psychology & Psychiatry, 61 (7), .
(doi:10.1111/jcpp.13187).
Abstract
Background:
Social Anxiety Disorder (SAD) aggregates in families. To elucidate intergenerational transmission of risk, we examined whether childhood SAD and symptoms of anxiety were prospectively predicted by stable infant temperamental inhibition, maternal SAD, maternal Generalized Anxiety Disorder (GAD), and maternal parenting behaviours.
Methods:
We conducted a longitudinal study beginning prenatally with follow-up at 4-, 10-, 14- and 58-months postnatally. Mothers were assessed for anxiety disorders prenatally and assigned to one of three groups: SAD (n=67), GAD (n=56), and non-anxious controls (n=94). We assessed infant temperamental inhibition at 4- and 14-months, maternal parenting behaviours at 10- and 58-months, and child anxiety disorders and symptoms at 58-months.
Results:
Child SAD at 58-months was predicted by prenatal maternal SAD (OR=23.76, 95%CI=1.15-60.37), but not by prenatal maternal GAD (OR = 7.44, 95% CI = 0.32-124.49), stable temperamental inhibition, or maternal behaviours. Child anxiety symptoms at 58-months were predicted specifically by maternal SAD (but not GAD), and also by concurrent maternal intrusiveness. Stable temperamental inhibition moderated the association between 10-month maternal encouragement and 58-month child anxiety symptoms.
Conclusions:
We found evidence for specificity of risk for child SAD and anxiety symptoms from maternal SAD compared to maternal GAD. Childhood anxiety symptoms were also predicted by an interaction between a lack of maternal encouragement in infancy and stable temperamental inhibition, as well as concurrent maternal intrusiveness. The findings have clinical implications for targeted prevention of child anxiety.
Text
revised manuscript 2 with highlihgted changes
- Accepted Manuscript
More information
Accepted/In Press date: 28 November 2019
e-pub ahead of print date: 8 January 2020
Published date: 1 July 2020
Additional Information:
Funding Information:
This work was supported by the ESRC and the MRC (UK). P.J.L. and C.C. were funded by an NIHR Research Professorship to C.C. (RP_2014‐04‐018). The views expressed are those of the authors and not necessarily those of the NHS, the NIHR, or the Department of Health. The authors would like to thank all the families who participated in the Reading Longitudinal Study, all the researchers who worked on this project, and particularly to Liz White who also provided support preparing this manuscript. The authors would also like to thank Nancy Snidman for providing training in assessment of infant temperament and confirmation of reliability of the research assistants. The authors have declared that they have no competing or potential conflicts of interest.
Publisher Copyright:
© 2020 Association for Child and Adolescent Mental Health
Keywords:
Anxiety, high risk studies, prevention, temperament
Identifiers
Local EPrints ID: 436227
URI: http://eprints.soton.ac.uk/id/eprint/436227
ISSN: 1469-7610
PURE UUID: 8d60e52a-a91a-465a-a247-78df0ea87317
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Date deposited: 04 Dec 2019 17:30
Last modified: 17 Mar 2024 05:06
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Contributors
Author:
Cathy Creswell
Author:
Peter J. Cooper
Author:
Lynne Murray
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