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Timeliness of childhood vaccination coverage: the Growing Up in Singapore Towards Healthy Outcomes Study

Timeliness of childhood vaccination coverage: the Growing Up in Singapore Towards Healthy Outcomes Study
Timeliness of childhood vaccination coverage: the Growing Up in Singapore Towards Healthy Outcomes Study
Studies investigating timeliness for childhood vaccination are limited especially in Asia. We examined the timeliness of vaccine administration and associated factors among infant and young children in Singapore. Total of 782 children born between November 2009 and July 2011 from a prospective cohort in Singapore were studied. Vaccination records from birth to 24 months of age were obtained from the National Immunization Registry of Singapore. Multivariable logistic regression models were performed. By 2 years of age, 92.8% of children in our cohort experienced a delay in receiving 1 or more vaccine doses according to the recommended national immunization schedule. When vaccinations were reviewed by series for each vaccine, 15.6% received all vaccine series outside the recommended age ranges. Factors associated with receiving vaccination series outside the recommended ages included maternal aged ≤35 years (OR 2.00; 95% CI 1.09, 3.66), Malay (1.71; 1.01, 2.89) or Indian ethnicity (2.06; 1.19, 3.59), low monthly household income (1.91; 1.14, 3.18), having at least four children (3.46; 1.62, 7.38), private (3.42; 1.80, 6.48) and multiple vaccination providers (3.91; 1.23, 12.48). These findings show an unacceptably high proportion of children experienced a delay in the receipt of their vaccinations. The identification of several demographic, socioeconomic, health-seeking behavioural and vaccine provider factors provides opportunities for targeted interventions to enhance the timeliness of childhood vaccination in Singapore
Age-appropriate, Childhood immunization, Coverage, Timeliness, Vaccination
283-292
Loy, See Ling
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Cheung, Yin Bun
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Chan, Jerry Kok Yen
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Soh, Shu E.
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Godfrey, Keith
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Tan, Kok Hian
672ae6c4-d4c8-4b1b-8512-efec36431503
Shek, Lynette P.
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Chong, Yap-Seng
492de658-aa9e-4b57-95bf-33109f4d2cc5
Lek, Ngee
517c4b9b-b6c9-4625-9db4-fd2b228b1755
Yap, Fabian
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Teoh, Oon Hoe
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Yung, Chee Fu
e0471853-a13f-4987-9c7c-60f4cf8ba9ff
Thoon, Koh Cheng
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Loy, See Ling
6fd10b64-1de2-419e-a5f4-b505be233e6e
Cheung, Yin Bun
c9beaf35-87d8-47f0-b41e-729e7820f991
Chan, Jerry Kok Yen
42e59d61-c3d1-486b-b33a-22c4645acf12
Soh, Shu E.
c2c8a830-001a-413e-a999-d0ecbc6c267d
Godfrey, Keith
0931701e-fe2c-44b5-8f0d-ec5c7477a6fd
Tan, Kok Hian
672ae6c4-d4c8-4b1b-8512-efec36431503
Shek, Lynette P.
9a77403c-0e0c-4536-a5ad-628ce94b279a
Chong, Yap-Seng
492de658-aa9e-4b57-95bf-33109f4d2cc5
Lek, Ngee
517c4b9b-b6c9-4625-9db4-fd2b228b1755
Yap, Fabian
22f6b954-31fc-4696-a52b-e985a424b95b
Teoh, Oon Hoe
b6523ca5-10fa-4b0d-b191-92d4162ea6c6
Yung, Chee Fu
e0471853-a13f-4987-9c7c-60f4cf8ba9ff
Thoon, Koh Cheng
fc134c70-1a6f-420d-b549-986e40f9bfd3

Loy, See Ling, Cheung, Yin Bun, Chan, Jerry Kok Yen, Soh, Shu E., Godfrey, Keith, Tan, Kok Hian, Shek, Lynette P., Chong, Yap-Seng, Lek, Ngee, Yap, Fabian, Teoh, Oon Hoe, Yung, Chee Fu and Thoon, Koh Cheng (2020) Timeliness of childhood vaccination coverage: the Growing Up in Singapore Towards Healthy Outcomes Study. Prevention Science, 21 (3), 283-292. (doi:10.1007/s11121-019-01078-2).

Record type: Article

Abstract

Studies investigating timeliness for childhood vaccination are limited especially in Asia. We examined the timeliness of vaccine administration and associated factors among infant and young children in Singapore. Total of 782 children born between November 2009 and July 2011 from a prospective cohort in Singapore were studied. Vaccination records from birth to 24 months of age were obtained from the National Immunization Registry of Singapore. Multivariable logistic regression models were performed. By 2 years of age, 92.8% of children in our cohort experienced a delay in receiving 1 or more vaccine doses according to the recommended national immunization schedule. When vaccinations were reviewed by series for each vaccine, 15.6% received all vaccine series outside the recommended age ranges. Factors associated with receiving vaccination series outside the recommended ages included maternal aged ≤35 years (OR 2.00; 95% CI 1.09, 3.66), Malay (1.71; 1.01, 2.89) or Indian ethnicity (2.06; 1.19, 3.59), low monthly household income (1.91; 1.14, 3.18), having at least four children (3.46; 1.62, 7.38), private (3.42; 1.80, 6.48) and multiple vaccination providers (3.91; 1.23, 12.48). These findings show an unacceptably high proportion of children experienced a delay in the receipt of their vaccinations. The identification of several demographic, socioeconomic, health-seeking behavioural and vaccine provider factors provides opportunities for targeted interventions to enhance the timeliness of childhood vaccination in Singapore

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manuscript (Prev Sci)_clean 26Nov2019 - Accepted Manuscript
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More information

Accepted/In Press date: 5 December 2019
e-pub ahead of print date: 20 February 2020
Keywords: Age-appropriate, Childhood immunization, Coverage, Timeliness, Vaccination

Identifiers

Local EPrints ID: 436397
URI: http://eprints.soton.ac.uk/id/eprint/436397
PURE UUID: bca4430b-690b-4ecc-95af-9a599986916d
ORCID for Keith Godfrey: ORCID iD orcid.org/0000-0002-4643-0618

Catalogue record

Date deposited: 10 Dec 2019 17:30
Last modified: 26 Nov 2021 06:31

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Contributors

Author: See Ling Loy
Author: Yin Bun Cheung
Author: Jerry Kok Yen Chan
Author: Shu E. Soh
Author: Keith Godfrey ORCID iD
Author: Kok Hian Tan
Author: Lynette P. Shek
Author: Yap-Seng Chong
Author: Ngee Lek
Author: Fabian Yap
Author: Oon Hoe Teoh
Author: Chee Fu Yung
Author: Koh Cheng Thoon

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