Clinical trials in oncology
Clinical trials in oncology
The development of a new treatment in cancer generally involves its assessment in Phase I, II and III prospective clinical trials. This article gives an overview of these phases of clinical trials, through which almost every new treatment must pass on the journey from its discovery in the laboratory to its routine use in clinical practice. The aim of the Phase I trial is to establish a dose, that of Phase II to evaluate activity, safety and feasibility, and that of Phase III to compare the new treatment against a suitable comparator.
Clinical trials, MRCP, Phase I, Phase II, Phase III, oncology
128-131
Griffiths, Gareth
7fd300c0-d279-4ff6-842d-aa1f2b9b864d
February 2020
Griffiths, Gareth
7fd300c0-d279-4ff6-842d-aa1f2b9b864d
Abstract
The development of a new treatment in cancer generally involves its assessment in Phase I, II and III prospective clinical trials. This article gives an overview of these phases of clinical trials, through which almost every new treatment must pass on the journey from its discovery in the laboratory to its routine use in clinical practice. The aim of the Phase I trial is to establish a dose, that of Phase II to evaluate activity, safety and feasibility, and that of Phase III to compare the new treatment against a suitable comparator.
Text
48-2Griffiths_edited cmw gg update
- Accepted Manuscript
More information
Accepted/In Press date: 31 December 2019
e-pub ahead of print date: 31 December 2019
Published date: February 2020
Additional Information:
Publisher Copyright:
© 2020
Keywords:
Clinical trials, MRCP, Phase I, Phase II, Phase III, oncology
Identifiers
Local EPrints ID: 437628
URI: http://eprints.soton.ac.uk/id/eprint/437628
ISSN: 1357-3039
PURE UUID: d6efdae0-7f5c-4448-a7b9-5d2e28ddf7cc
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Date deposited: 07 Feb 2020 17:30
Last modified: 17 Mar 2024 05:12
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