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Obesity is a risk factor for greater COVID-19 severity

Obesity is a risk factor for greater COVID-19 severity
Obesity is a risk factor for greater COVID-19 severity
The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has attracted increasing worldwide attention. Obesity commonly aggravates the severity of respiratory diseases, but it is currently not known whether obese patients are also more likely to have greater COVID-19 severity of illness. We investigated the association between obesity and COVID-19 severity of illness among patients with laboratory-confirmed SARS-CoV-2 infection.
1935-5548
e72-e74
Gao, Feng
b70fc7ee-1c00-4b32-aa1a-272e603a3add
Zheng, Kenneth I.
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Wang, Xiao-Bo
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Sun, Qing-Feng
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Pan, Ke-Hua
f6e72d36-a409-46c7-9bd4-03edd8627810
Wang, Ting-Yao
ee02f4df-e228-4878-bf40-228d6c220710
Targher, Giovanni
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Byrne, Christopher
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George, Jacob
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Zheng, Ming-Hua
91a85ca0-f707-48d6-baaa-e3c31e3b541b
Gao, Feng
b70fc7ee-1c00-4b32-aa1a-272e603a3add
Zheng, Kenneth I.
662431a5-0fcf-4abe-aaa5-3e119020ba02
Wang, Xiao-Bo
2ad2ac62-c524-4dc6-a18e-b51f4907ef1a
Sun, Qing-Feng
0bc8ef5b-f9a0-4c64-989e-b8ebfab822ce
Pan, Ke-Hua
f6e72d36-a409-46c7-9bd4-03edd8627810
Wang, Ting-Yao
ee02f4df-e228-4878-bf40-228d6c220710
Targher, Giovanni
043e0811-b389-4922-974e-22e650212c5f
Byrne, Christopher
1370b997-cead-4229-83a7-53301ed2a43c
George, Jacob
72bea26d-6264-415b-a41e-e90a6b2ee1f8
Zheng, Ming-Hua
91a85ca0-f707-48d6-baaa-e3c31e3b541b

Gao, Feng, Zheng, Kenneth I., Wang, Xiao-Bo, Sun, Qing-Feng, Pan, Ke-Hua, Wang, Ting-Yao, Targher, Giovanni, Byrne, Christopher, George, Jacob and Zheng, Ming-Hua (2020) Obesity is a risk factor for greater COVID-19 severity. Diabetes Care, 43 (7), e72-e74, [dc200682]. (doi:10.2337/dc20-0682).

Record type: Article

Abstract

The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has attracted increasing worldwide attention. Obesity commonly aggravates the severity of respiratory diseases, but it is currently not known whether obese patients are also more likely to have greater COVID-19 severity of illness. We investigated the association between obesity and COVID-19 severity of illness among patients with laboratory-confirmed SARS-CoV-2 infection.

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Accepted/In Press date: 8 April 2020
e-pub ahead of print date: 14 May 2020
Published date: 1 July 2020
Additional Information: Funding Information: Acknowledgments. The authors thank Hong-Lei Ma (NAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University) and Wen-Yue Liu (Department of Endocrinology, the First Affiliated Hospital of Wenzhou Medical University) for data collection assistance. This work is a part of the PERSONS study. Funding. This work was supported by a grant from the National Natural Science Foundation of China (81500665) as well as funding from the Ruian Science and Technology Bureau (2020023), High Level Creative Talents from Department of Public Health in Zhejiang Province, and Project of New Century 551 Talent Nurturing in Wenzhou. G.T. is supported in part by grants from the School of Medicine, University of Verona, Verona, Italy. C.D.B. is supported in part by the Southampton National Institute for Health Research Biomedical Research Centre (IS-BRC-20004), U.K. Duality of Interest. No potential conflicts of interest relevant to this article were reported. Author Contributions. F.G., K.I.Z., and M.-H.Z. contributed to study concept and design. X.-B.W., Q-F.S., K.-H.P., T.-Y.W., and Y.-P.C. contributed to acquisition of data. F.G. and K.I.Z. contributed to analysis and interpretation of data. F.G. and K.I.Z. drafted the manuscript. G.T., C.D.B., and J.G. critically revised the manuscript for important intellectual content. M.-H.Z. supervised the study. All authors contributed to the manuscript for important intellectual content and approved the submission. M.-H.Z. is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.

Identifiers

Local EPrints ID: 439542
URI: http://eprints.soton.ac.uk/id/eprint/439542
ISSN: 1935-5548
PURE UUID: 75e635f9-da39-4268-8099-0e471e3148c7
ORCID for Christopher Byrne: ORCID iD orcid.org/0000-0001-6322-7753

Catalogue record

Date deposited: 27 Apr 2020 16:30
Last modified: 17 Mar 2024 05:29

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Contributors

Author: Feng Gao
Author: Kenneth I. Zheng
Author: Xiao-Bo Wang
Author: Qing-Feng Sun
Author: Ke-Hua Pan
Author: Ting-Yao Wang
Author: Giovanni Targher
Author: Jacob George
Author: Ming-Hua Zheng

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