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Approaches to the diagnosis and prevention of frailty

Approaches to the diagnosis and prevention of frailty
Approaches to the diagnosis and prevention of frailty
An individual who is living with frailty has impairments in homeostasis across several body systems and is more vulnerable to stressors that may ultimately predispose them to negative health-related outcomes, disability and increased healthcare use. Approximately a quarter of individuals aged > 85 years are living with frailty and as such the identification of those who are frail is a public health priority. Given that the syndrome of frailty is defined by progressive and gradual loss of physiological reserves there is much scope to attempt to modify the trajectory of the frailty syndrome via physical activity and nutritional interventions. In this review we give an up to date account on the identification of frailty in clinical practice and offer insights into physical activity and nutritional strategies that may be beneficial to modify or reverse the frailty syndrome.
Frailty, Identifying frailty, Nutrition, Physical activity
1594-0667
1629-1637
Woolford, S.J.
a123d451-d086-45c0-a961-8704f5e90c90
Sohan, O.
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Dennison, E.M.
ee647287-edb4-4392-8361-e59fd505b1d1
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Patel, H.P.
e1c0826f-d14e-49f3-8049-5b945d185523
Woolford, S.J.
a123d451-d086-45c0-a961-8704f5e90c90
Sohan, O.
a4df9f2c-6141-4158-972c-3bf440f5a31c
Dennison, E.M.
ee647287-edb4-4392-8361-e59fd505b1d1
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Patel, H.P.
e1c0826f-d14e-49f3-8049-5b945d185523

Woolford, S.J., Sohan, O., Dennison, E.M., Cooper, C. and Patel, H.P. (2020) Approaches to the diagnosis and prevention of frailty. Aging Clinical and Experimental Research, 32 (9), 1629-1637. (doi:10.1007/s40520-020-01559-3).

Record type: Review

Abstract

An individual who is living with frailty has impairments in homeostasis across several body systems and is more vulnerable to stressors that may ultimately predispose them to negative health-related outcomes, disability and increased healthcare use. Approximately a quarter of individuals aged > 85 years are living with frailty and as such the identification of those who are frail is a public health priority. Given that the syndrome of frailty is defined by progressive and gradual loss of physiological reserves there is much scope to attempt to modify the trajectory of the frailty syndrome via physical activity and nutritional interventions. In this review we give an up to date account on the identification of frailty in clinical practice and offer insights into physical activity and nutritional strategies that may be beneficial to modify or reverse the frailty syndrome.

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Accepted/In Press date: 16 April 2020
e-pub ahead of print date: 30 April 2020
Published date: 1 September 2020
Additional Information: Funding Information: SJW, OS and HPP are supported by the Department of Medicine for Older People, University Hospital Southampton, Southampton, UK. EMD and CC are supported by the Medical Research Council, UK. HPP is supported by the NIHR Southampton Biomedical Research Centre, Nutrition and the University of Southampton. This report is independent research and the views expressed in this publication are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health. These funding bodies had no role in writing of the manuscript or decision to submit for publication. Publisher Copyright: © 2020, The Author(s).
Keywords: Frailty, Identifying frailty, Nutrition, Physical activity

Identifiers

Local EPrints ID: 440936
URI: http://eprints.soton.ac.uk/id/eprint/440936
ISSN: 1594-0667
PURE UUID: 8f22091c-8da5-426a-9a59-779d2e874124
ORCID for E.M. Dennison: ORCID iD orcid.org/0000-0002-3048-4961
ORCID for C. Cooper: ORCID iD orcid.org/0000-0003-3510-0709
ORCID for H.P. Patel: ORCID iD orcid.org/0000-0002-0081-1802

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Date deposited: 22 May 2020 16:40
Last modified: 23 Jul 2022 01:57

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Contributors

Author: S.J. Woolford
Author: O. Sohan
Author: E.M. Dennison ORCID iD
Author: C. Cooper ORCID iD
Author: H.P. Patel ORCID iD

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