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Osteoporosis Epidemiology Using International Cohorts

Osteoporosis Epidemiology Using International Cohorts
Osteoporosis Epidemiology Using International Cohorts
Purpose of review: the field of osteoporosis research has been active for the past 20 years, and has allowed significant advancement in the management of osteoporosis. This review will give an overview of the latest data from international cohorts that relate to current and recent osteoporosis research.

Recent findings: the clinical diagnosis of osteoporosis relies heavily on BMD measured at femoral neck or spine and although BMD has excellent predictive value for future fractures, fracture risk assessment has evolved over the years, resulting in the birth of fracture prediction tools. Fracture risk factors not currently featured in these tools are being considered for inclusion, including imminent risk fracture following a sentinel fracture, number of falls, and previous vertebral fractures. Data from groups with comorbidities such as COPD are helping us understand how to best manage patients with multiple co-morbidities. Finally, the prevalence of vertebral fracture in the older general population and other selected populations have been explored, alongside the global burden of osteoporosis and its consequences.

Summary: our understanding of osteoporosis continues to expand, but knowledge gaps
cohort, comorbidities, epidemiology, fracture, osteoporosis
1040-8711
387-393
Zhang, Jean
437abe90-46ac-46de-8183-042c36ed3398
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
Prieto-Alhambra, Daniel
e596722a-2f01-4201-bd9d-be3e180e76a9
Zhang, Jean
437abe90-46ac-46de-8183-042c36ed3398
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
Prieto-Alhambra, Daniel
e596722a-2f01-4201-bd9d-be3e180e76a9

Zhang, Jean, Dennison, Elaine and Prieto-Alhambra, Daniel (2020) Osteoporosis Epidemiology Using International Cohorts. Current Opinion in Rheumatology, 32 (4), 387-393. (doi:10.1097/BOR.0000000000000722).

Record type: Article

Abstract

Purpose of review: the field of osteoporosis research has been active for the past 20 years, and has allowed significant advancement in the management of osteoporosis. This review will give an overview of the latest data from international cohorts that relate to current and recent osteoporosis research.

Recent findings: the clinical diagnosis of osteoporosis relies heavily on BMD measured at femoral neck or spine and although BMD has excellent predictive value for future fractures, fracture risk assessment has evolved over the years, resulting in the birth of fracture prediction tools. Fracture risk factors not currently featured in these tools are being considered for inclusion, including imminent risk fracture following a sentinel fracture, number of falls, and previous vertebral fractures. Data from groups with comorbidities such as COPD are helping us understand how to best manage patients with multiple co-morbidities. Finally, the prevalence of vertebral fracture in the older general population and other selected populations have been explored, alongside the global burden of osteoporosis and its consequences.

Summary: our understanding of osteoporosis continues to expand, but knowledge gaps

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OP International paper V6 No Endnote Submission - Accepted Manuscript
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More information

Accepted/In Press date: 8 May 2020
e-pub ahead of print date: July 2020
Keywords: cohort, comorbidities, epidemiology, fracture, osteoporosis

Identifiers

Local EPrints ID: 441256
URI: http://eprints.soton.ac.uk/id/eprint/441256
ISSN: 1040-8711
PURE UUID: a482081c-1ee7-425a-ad90-aa7b06b47309
ORCID for Elaine Dennison: ORCID iD orcid.org/0000-0002-3048-4961

Catalogue record

Date deposited: 08 Jun 2020 16:30
Last modified: 26 Nov 2021 06:16

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Contributors

Author: Jean Zhang
Author: Elaine Dennison ORCID iD
Author: Daniel Prieto-Alhambra

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