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Eating behaviors moderate the associations between risk factors in the first 1,000 days and adiposity outcomes at 6 years of age

Eating behaviors moderate the associations between risk factors in the first 1,000 days and adiposity outcomes at 6 years of age
Eating behaviors moderate the associations between risk factors in the first 1,000 days and adiposity outcomes at 6 years of age
Background: Several risk factors in the first 1,000 days are linked with increased obesity risk in later childhood. The role of potentially modifiable eating behaviors in this association is unclear. Objective: This study examined if the association between cumulated risk factors in the first 1,000 days and adiposity at 6 years is moderated by eating behaviors. Design: Participants were 302 children from the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort. Risk factors included maternal pre-pregnancy and paternal overweight, excessive gestational weight gain, raised fasting glucose during pregnancy, short breastfeeding duration and early introduction of solid foods. Composite risk scores reflecting the prevalence and the importance of risk factors present were computed. Adiposity outcomes were child BMI and sum of skinfolds (SSF), and candidate eating behavior moderators were portion size, eating rate, and energy intake during lunch and in an eating in the absence of hunger task. Results: Higher composite risk score predicted higher BMI z-scores (B= 0.08, 95%CI [0.04, 0.13]) and larger SSF (0.70 [0.23, 1.18]mm), and was associated with larger self-served food portions (5.03 [0.47, 9.60] kcal), faster eating rates (0.40 [0.21, 0.59] g/min) and larger lunch intakes (7.05 [3.37, 10.74] kcal). Importantly, the association between composite risk score and adiposity was moderated by eating behaviors. The composite risk score was unrelated to SSF in children who selected smaller food portions, ate slower, and consumed less energy, but was positively associated with SSF among children who selected larger food portions, ate faster, and consumed more energy (eating behavior*risk score interactions p<0.05). Conclusions: The association between risk factors in the first 1,000 days and adiposity at 6 years varies by eating behaviors, highlighting modifiable behavioral targets for interventions
0002-9165
997-1006
Fogel, Anna
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McCrickerd, Keri
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Aris, Izzuddin M.
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Goh, Ai Ting
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Chong, Yap-Seng
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Tan, Kok Hian
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Yap, Fabian
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Shek, Lynette P.
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Meaney, Michael J.
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Broekman, Birit F.P.
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Godfrey, Keith
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Chong, Mary Foong-Fong
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Cai, Shirong
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Pang, Wei Wei
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Yuan, Wen Lun
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Lee, Yung Seng
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Forde, Ciaran G
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Fogel, Anna
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McCrickerd, Keri
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Aris, Izzuddin M.
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Goh, Ai Ting
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Chong, Yap-Seng
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Tan, Kok Hian
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Yap, Fabian
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Shek, Lynette P.
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Meaney, Michael J.
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Broekman, Birit F.P.
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Godfrey, Keith
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Chong, Mary Foong-Fong
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Cai, Shirong
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Pang, Wei Wei
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Yuan, Wen Lun
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Lee, Yung Seng
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Forde, Ciaran G
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Fogel, Anna, McCrickerd, Keri, Aris, Izzuddin M., Goh, Ai Ting, Chong, Yap-Seng, Tan, Kok Hian, Yap, Fabian, Shek, Lynette P., Meaney, Michael J., Broekman, Birit F.P., Godfrey, Keith, Chong, Mary Foong-Fong, Cai, Shirong, Pang, Wei Wei, Yuan, Wen Lun, Lee, Yung Seng and Forde, Ciaran G (2020) Eating behaviors moderate the associations between risk factors in the first 1,000 days and adiposity outcomes at 6 years of age. American Journal of Clinical Nutrition, 997-1006. (doi:10.1093/ajcn/nqaa052).

Record type: Article

Abstract

Background: Several risk factors in the first 1,000 days are linked with increased obesity risk in later childhood. The role of potentially modifiable eating behaviors in this association is unclear. Objective: This study examined if the association between cumulated risk factors in the first 1,000 days and adiposity at 6 years is moderated by eating behaviors. Design: Participants were 302 children from the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort. Risk factors included maternal pre-pregnancy and paternal overweight, excessive gestational weight gain, raised fasting glucose during pregnancy, short breastfeeding duration and early introduction of solid foods. Composite risk scores reflecting the prevalence and the importance of risk factors present were computed. Adiposity outcomes were child BMI and sum of skinfolds (SSF), and candidate eating behavior moderators were portion size, eating rate, and energy intake during lunch and in an eating in the absence of hunger task. Results: Higher composite risk score predicted higher BMI z-scores (B= 0.08, 95%CI [0.04, 0.13]) and larger SSF (0.70 [0.23, 1.18]mm), and was associated with larger self-served food portions (5.03 [0.47, 9.60] kcal), faster eating rates (0.40 [0.21, 0.59] g/min) and larger lunch intakes (7.05 [3.37, 10.74] kcal). Importantly, the association between composite risk score and adiposity was moderated by eating behaviors. The composite risk score was unrelated to SSF in children who selected smaller food portions, ate slower, and consumed less energy, but was positively associated with SSF among children who selected larger food portions, ate faster, and consumed more energy (eating behavior*risk score interactions p<0.05). Conclusions: The association between risk factors in the first 1,000 days and adiposity at 6 years varies by eating behaviors, highlighting modifiable behavioral targets for interventions

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Accepted/In Press date: 25 February 2020
e-pub ahead of print date: 27 March 2020
Published date: 1 May 2020

Identifiers

Local EPrints ID: 441343
URI: http://eprints.soton.ac.uk/id/eprint/441343
ISSN: 0002-9165
PURE UUID: 90ae06cc-1614-494e-a4eb-477eaf83f1bf
ORCID for Keith Godfrey: ORCID iD orcid.org/0000-0002-4643-0618

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Date deposited: 10 Jun 2020 16:30
Last modified: 26 Nov 2021 07:17

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Contributors

Author: Anna Fogel
Author: Keri McCrickerd
Author: Izzuddin M. Aris
Author: Ai Ting Goh
Author: Yap-Seng Chong
Author: Kok Hian Tan
Author: Fabian Yap
Author: Lynette P. Shek
Author: Michael J. Meaney
Author: Birit F.P. Broekman
Author: Keith Godfrey ORCID iD
Author: Mary Foong-Fong Chong
Author: Shirong Cai
Author: Wei Wei Pang
Author: Wen Lun Yuan
Author: Yung Seng Lee
Author: Ciaran G Forde

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