Association between mental disorders and somatic conditions: protocol for an umbrella review
Association between mental disorders and somatic conditions: protocol for an umbrella review
Introduction: Although several systematic reviews (SRs)/meta-analyses (MAs) on the association between specific mental disorders and specific somatic conditions are available, an overarching evidence synthesis across mental disorders and somatic conditions is currently lacking. We will conduct an umbrella review of SRs/MAs to test: 1) the strength of the association between individual mental disorders and individual somatic conditions in children/adolescents and adults; 2) to which extent associations are specific to individual mental and somatic conditions . Methods and analysis: We will search a broad set of electronic databases and contact study authors. We will include SRs with MA or SRs reporting the effect size from individual studies on the association between a number of somatic and mental conditions (as per the International Classification of Diseases, 11th Revision). We will follow an algorithm to select only one SR or MA when more than one are available on the same association. We will rate the quality of included SRs/MAs using the AMSTAR-2 tool. We will assess to which extent mental disorders are selectively associated with specific somatic conditions or if there are transdiagnostic, across-spectra or diagnostic spectrum-specific associations between mental disorders and somatic conditions based on the Transparent, Reporting, Appraising, Numerating, Showing (TRANSD) recommendations. Discussion: The present umbrella review will shed light on the association between mental health disorders and somatic conditions, providing useful data for the care of patients with mental health disorders, in particular for early detection and intervention. This work might also add insight to the pathophysiology of mental health conditions, and contribute to the current debate on the value of a transdiagnostic approach in psychiatry.
135-139
Cortese, Samuele
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Solmi, Marco
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Arrondo, Gonzalo
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Cipriani, Andrea
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Fusar-Poli, Paolo
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Larsson, Henrik
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Correll, Christoph U.
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28 October 2020
Cortese, Samuele
53d4bf2c-4e0e-4c77-9385-218350560fdb
Solmi, Marco
256504f2-483a-4b42-bfab-081c6a617867
Arrondo, Gonzalo
5b9c1446-74f9-4dc7-aa73-6c67f3eaddbc
Cipriani, Andrea
5f3097c8-4901-4a9b-b371-d17aeac9b686
Fusar-Poli, Paolo
a1ac1bbb-1ffd-4078-98df-d7918650bd2c
Larsson, Henrik
4132f7c6-5d52-43a1-be38-d343e67107cf
Correll, Christoph U.
d1a6c4a7-3911-4ffb-9d9d-4d70f6b574b1
Cortese, Samuele, Solmi, Marco, Arrondo, Gonzalo, Cipriani, Andrea, Fusar-Poli, Paolo, Larsson, Henrik and Correll, Christoph U.
(2020)
Association between mental disorders and somatic conditions: protocol for an umbrella review.
Evidence-Based Mental Health, 23 (4), .
(doi:10.1136/ebmental-2020-300158).
Abstract
Introduction: Although several systematic reviews (SRs)/meta-analyses (MAs) on the association between specific mental disorders and specific somatic conditions are available, an overarching evidence synthesis across mental disorders and somatic conditions is currently lacking. We will conduct an umbrella review of SRs/MAs to test: 1) the strength of the association between individual mental disorders and individual somatic conditions in children/adolescents and adults; 2) to which extent associations are specific to individual mental and somatic conditions . Methods and analysis: We will search a broad set of electronic databases and contact study authors. We will include SRs with MA or SRs reporting the effect size from individual studies on the association between a number of somatic and mental conditions (as per the International Classification of Diseases, 11th Revision). We will follow an algorithm to select only one SR or MA when more than one are available on the same association. We will rate the quality of included SRs/MAs using the AMSTAR-2 tool. We will assess to which extent mental disorders are selectively associated with specific somatic conditions or if there are transdiagnostic, across-spectra or diagnostic spectrum-specific associations between mental disorders and somatic conditions based on the Transparent, Reporting, Appraising, Numerating, Showing (TRANSD) recommendations. Discussion: The present umbrella review will shed light on the association between mental health disorders and somatic conditions, providing useful data for the care of patients with mental health disorders, in particular for early detection and intervention. This work might also add insight to the pathophysiology of mental health conditions, and contribute to the current debate on the value of a transdiagnostic approach in psychiatry.
Text
200603_Cortese_MAIN_TEXT_R1_clean
- Accepted Manuscript
More information
Accepted/In Press date: 25 July 2020
e-pub ahead of print date: 8 September 2020
Published date: 28 October 2020
Identifiers
Local EPrints ID: 443171
URI: http://eprints.soton.ac.uk/id/eprint/443171
ISSN: 1362-0347
PURE UUID: c0fa5218-9b7d-455c-97f5-efa4ae2d93e0
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Date deposited: 13 Aug 2020 16:37
Last modified: 17 Mar 2024 05:48
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Contributors
Author:
Marco Solmi
Author:
Gonzalo Arrondo
Author:
Andrea Cipriani
Author:
Paolo Fusar-Poli
Author:
Henrik Larsson
Author:
Christoph U. Correll
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