Prevalence of attention-deficit/hyperactivity disorder in older adults: a systematic review and meta-analysis
Prevalence of attention-deficit/hyperactivity disorder in older adults: a systematic review and meta-analysis
There is a significant knowledge gap in research on Attention-Deficit/Hyperactivity Disorder (ADHD) in older adults. Via a systematic review and meta-analysis, we aimed to investigate the prevalence of ADHD in older adults, considering different assessment methods. We searched five electronic databases up to June 26, 2020. We identified 20 relevant studies with 32 datasets providing a total sample size of 20,999,871 individuals (41,420 individuals with ADHD). The pooled prevalence estimates differed significantly across assessment methods: 2.18 % (95 % CI = 1.51, 3.16) based on research diagnosis via validated scales, 0.23 % (0.12, 0.43) relying on clinical ADHD diagnosis, and 0.09 % (0.06, 0.15) based on ADHD treatment rates. Heterogeneity was significant across studies for all assessment methods. There is a considerable number of older adults with elevated levels of ADHD symptoms as determined via validated scales, and the prevalence of treated ADHD is less than half of the prevalence of clinically diagnosed ADHD. This highlights the need for increased awareness of ADHD clinical diagnosis and treatment in older adults.
Attention-deficit/hyperactivity disorder, Meta-analysis, Older adults, Prevalence, Systematic review
282-289
Dobrosavljevi, Maja
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Solares, Carmen
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Cortese, Samuele
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Andershed, Henrik
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Larsson, Henrik
e7862feb-95bc-4b96-a765-ae278738e980
November 2020
Dobrosavljevi, Maja
bfa61ce9-efa5-4838-9c38-6764698e1689
Solares, Carmen
d2f8a22d-e302-41c6-af9a-2c979b247655
Cortese, Samuele
53d4bf2c-4e0e-4c77-9385-218350560fdb
Andershed, Henrik
0a69fc64-bf02-4c09-9805-12d656eb6c19
Larsson, Henrik
e7862feb-95bc-4b96-a765-ae278738e980
Dobrosavljevi, Maja, Solares, Carmen, Cortese, Samuele, Andershed, Henrik and Larsson, Henrik
(2020)
Prevalence of attention-deficit/hyperactivity disorder in older adults: a systematic review and meta-analysis.
Neuroscience & Biobehavioral Reviews, 118, .
(doi:10.1016/j.neubiorev.2020.07.042).
Abstract
There is a significant knowledge gap in research on Attention-Deficit/Hyperactivity Disorder (ADHD) in older adults. Via a systematic review and meta-analysis, we aimed to investigate the prevalence of ADHD in older adults, considering different assessment methods. We searched five electronic databases up to June 26, 2020. We identified 20 relevant studies with 32 datasets providing a total sample size of 20,999,871 individuals (41,420 individuals with ADHD). The pooled prevalence estimates differed significantly across assessment methods: 2.18 % (95 % CI = 1.51, 3.16) based on research diagnosis via validated scales, 0.23 % (0.12, 0.43) relying on clinical ADHD diagnosis, and 0.09 % (0.06, 0.15) based on ADHD treatment rates. Heterogeneity was significant across studies for all assessment methods. There is a considerable number of older adults with elevated levels of ADHD symptoms as determined via validated scales, and the prevalence of treated ADHD is less than half of the prevalence of clinically diagnosed ADHD. This highlights the need for increased awareness of ADHD clinical diagnosis and treatment in older adults.
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Accepted/In Press date: 31 July 2020
e-pub ahead of print date: 12 August 2020
Published date: November 2020
Additional Information:
Funding Information:
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 754285 .
Funding Information:
HL acknowledges financial support from the Swedish Research Council ( 2018-02599 ) and the Swedish Brain Foundation ( FO2018-0273 ).
Publisher Copyright:
© 2020 The Author(s)
Keywords:
Attention-deficit/hyperactivity disorder, Meta-analysis, Older adults, Prevalence, Systematic review
Identifiers
Local EPrints ID: 443172
URI: http://eprints.soton.ac.uk/id/eprint/443172
ISSN: 0149-7634
PURE UUID: cfad9f87-55cf-4615-a091-78c22a83feeb
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Date deposited: 13 Aug 2020 16:37
Last modified: 17 Mar 2024 05:48
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Contributors
Author:
Maja Dobrosavljevi
Author:
Carmen Solares
Author:
Henrik Andershed
Author:
Henrik Larsson
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