Microglial contribution to synaptic uptake in the prefrontal cortex in schizophrenia

Accepted/In Press date: 22 August 2020

e-pub ahead of print date: 6 September 2020

Published date: 1 February 2021

Additional Information: Funding Information: We would like to thank our funders, specifically the UK Dementia Research Institute which receives funding from Alzheimer?s Research UK, the Alzheimer?s Society, and the Medical Research Council. We also would like to thank the Wellcome Trust for funding AJS and TLSJ. Tissue samples were obtained from The Corsellis Collection as part of the UK Brain Archive Information Network (BRAIN UK) which is funded by the Medical Research Council and Brain Tumour Research. Ethics approval was provided by BRAIN UK, a virtual brain bank which encompasses the archives of neuropathology departments in the UK and the Corsellis Collection, ethics reference 14/SC/0098. The study was registered under the Ethics and Research Governance (ERGO) of the Southampton University (Reference 19791). Authors contributed in the following ways: MT contributed to the study design, performed experiments and imaging, statistical analysis and manuscript preparation; AJS contributed to statistical analysis and manuscript editing; DB contributed by providing cut paraffin-embedded section, study design and manuscript editing; TLSJ contributed the study design, statistical analysis and manuscript editing. TLSJ is on the Scientific Advisory Board of Cognition Therapeutics and receives collaborative grant funding from two industry partners. None of these had any influence over this paper. None of remaining authors declare any conflicts of interest. Figures were created with BioRender.com. Funding Information: We would like to thank our funders, specifically the UK Dementia Research Institute which receives funding from Alzheimer’s Research UK, the Alzheimer’s Society, and the Medical Research Council. We also would like to thank the Wellcome Trust for funding AJS and TLSJ. Tissue samples were obtained from The Corsellis Collection as part of the UK Brain Archive Information Network (BRAIN UK) which is funded by the Medical Research Council and Brain Tumour Research. Ethics approval was provided by BRAIN UK, a virtual brain bank which encompasses the archives of neuropathology departments in the UK and the Corsellis Collection, ethics reference 14/SC/0098. The study was registered under the Ethics and Research Governance (ERGO) of the Southampton University (Reference 19791). Authors contributed in the following ways: MT contributed to the study design, performed experiments and imaging, statistical analysis and manuscript preparation; AJS contributed to statistical analysis and manuscript editing; DB contributed by providing cut paraffin‐embedded section, study design and manuscript editing; TLSJ contributed the study design, statistical analysis and manuscript editing. TLSJ is on the Scientific Advisory Board of Cognition Therapeutics and receives collaborative grant funding from two industry partners. None of these had any influence over this paper. None of remaining authors declare any conflicts of interest. Figures were created with BioRender.com.

Local EPrints ID: 443455

URI: http://eprints.soton.ac.uk/id/eprint/443455

DOI: doi:10.1111/nan.12660

ISSN: 0305-1846

PURE UUID: 7066f376-4b32-4187-a4a7-a90f6e1adabe

ORCID for Delphine Boche: orcid.org/0000-0002-5884-130X

Date deposited: 26 Aug 2020 16:34

Last modified: 17 Mar 2024 02:51