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House dust mite sensitization, eczema and wheeze increase risk of shellfish sensitization

House dust mite sensitization, eczema and wheeze increase risk of shellfish sensitization
House dust mite sensitization, eczema and wheeze increase risk of shellfish sensitization
Shellfish allergy is more prevalent in South‐East Asia (~5%1) than in Western populations (e.g. United States ~2‐3%.2). Typically commencing in late childhood, it is the leading cause of anaphylaxis in adolescents and adults in Asia. Cross‐sectional studies have demonstrated a high correlation between shellfish and house dust mite (HDM) sensitization in warm, humid climates and urban environments where HDM are ubiquitous. The major shellfish allergen, tropomyosin, shares ~80% structural homology with HDM tropomyosin, and primary sensitization to dust mite tropomyosin has been hypothesized to induce cross‐sensitization to shellfish.
0905-6157
1096-1099
Loo, Evelyn Xiu-Ling
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Lau, Hui Xing
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Suaini, Noor Hidayatul Aini
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Wong, Lydia Su Yin
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Goh, Anne Eng Neo
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Teoh, Oon Hoe
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van Bever, Hugo
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Shek, Lynette Pei-Chi
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Lee, Bee Wah
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Tan, Kok Hian
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Godfrey, Keith
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Eriksson, Johan Gunnar
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Chong, Yap-Seng
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Tham, Elizabeth Huiwen
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Loo, Evelyn Xiu-Ling
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Lau, Hui Xing
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Suaini, Noor Hidayatul Aini
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Wong, Lydia Su Yin
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Goh, Anne Eng Neo
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Teoh, Oon Hoe
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van Bever, Hugo
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Shek, Lynette Pei-Chi
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Lee, Bee Wah
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Tan, Kok Hian
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Godfrey, Keith
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Eriksson, Johan Gunnar
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Chong, Yap-Seng
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Tham, Elizabeth Huiwen
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Loo, Evelyn Xiu-Ling, Lau, Hui Xing, Suaini, Noor Hidayatul Aini, Wong, Lydia Su Yin, Goh, Anne Eng Neo, Teoh, Oon Hoe, van Bever, Hugo, Shek, Lynette Pei-Chi, Lee, Bee Wah, Tan, Kok Hian, Godfrey, Keith, Eriksson, Johan Gunnar, Chong, Yap-Seng and Tham, Elizabeth Huiwen (2021) House dust mite sensitization, eczema and wheeze increase risk of shellfish sensitization. Pediatric Allergy and Immunology, 32 (5), 1096-1099. (doi:10.1111/pai.13493).

Record type: Letter

Abstract

Shellfish allergy is more prevalent in South‐East Asia (~5%1) than in Western populations (e.g. United States ~2‐3%.2). Typically commencing in late childhood, it is the leading cause of anaphylaxis in adolescents and adults in Asia. Cross‐sectional studies have demonstrated a high correlation between shellfish and house dust mite (HDM) sensitization in warm, humid climates and urban environments where HDM are ubiquitous. The major shellfish allergen, tropomyosin, shares ~80% structural homology with HDM tropomyosin, and primary sensitization to dust mite tropomyosin has been hypothesized to induce cross‐sensitization to shellfish.

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Shellfish HDM paper revised clean 010221 - Accepted Manuscript
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More information

Accepted/In Press date: 2 March 2021
e-pub ahead of print date: 9 March 2021
Published date: July 2021
Additional Information: Funding Information: We thank the GUSTO study group and all clinical and home-visit staff involved. The voluntary participation of all subjects is greatly appreciated. The GUSTO study team includes Airu Chia, Allan Sheppard, Amutha Chinnadurai, Anna Magdalena Fogel, Anne Eng Neo Goh, Anne Hin Yee Chu, Anne Rifkin-Graboi, Anqi Qiu, Arijit Biswas, Bee Wah Lee, Birit Froukje Philipp Broekman, Bobby Kyungbeom Cheon, Boon Long Quah, Candida Vaz, Chai Kiat Chng, Cheryl Shufen Ngo, Choon Looi Bong, Christiani Jeyakumar Henry, Ciaran Gerard Forde, Claudia Chi, Daniel Yam Thiam Goh, Dawn Xin Ping Koh, Desiree Y. Phua, Doris Ngiuk Lan Loh, E Shyong Tai, Elaine Kwang Hsia Tham, Elaine Phaik Ling Quah, Elizabeth Huiwen Tham, Evelyn Chung Ning Law, Evelyn Xiu Ling Loo, Fabian Kok Peng Yap, Faidon Magkos, Falk Mueller-Riemenschneider, George Seow Heong Yeo, Hannah Ee Juen Yong, Helen Yu Chen, Heng Hao Tan, Hong Pan, Hugo P S van Bever, Hui Min Tan, Iliana Magiati, Inez Bik Yun Wong, Ivy Yee-Man Lau, Izzuddin Bin Mohd Aris, Jeannie Tay, Jeevesh Kapur, Jenny L. Richmond, Jerry Kok Yen Chan, Jia Xu, Joanna Dawn Holbrook, Joanne Su-Yin Yoong, Joao Nuno Andrade Requicha Ferreira, Johan Gunnar Eriksson, Jonathan Tze Liang Choo, Jonathan Y. Bernard, Jonathan Yinhao Huang, Joshua J. Gooley, Jun Shi Lai, Karen Mei Ling Tan, Keith M. Godfrey, Kenneth Yung Chiang Kwek, Keri McCrickerd, Kok Hian Tan, Kothandaraman Narasimhan, Krishnamoorthy Naiduvaje, Kuan Jin Lee, Leher Singh, Li Chen, Lieng Hsi Ling, Lin Lin Su, Ling-Wei Chen, Lourdes Mary Daniel, Lynette Pei-Chi Shek, Marielle V. Fortier, Mark Hanson, Mary Foong-Fong Chong, Mary Rauff, Mei Chien Chua, Melvin Khee-Shing Leow, Michael J. Meaney, Michelle Zhi Ling Kee, Min Gong, Mya Thway Tint, Navin Michael, Neerja Karnani, Ngee Lek, Oon Hoe Teoh, P. C. Wong, Paulin Tay Straughan, Peter David Gluckman, Pratibha Keshav Agarwal, Priti Mishra, Queenie Ling Jun Li, Rob Martinus van Dam, Salome A. Rebello, Sambasivam Sendhil Velan, Seang Mei Saw, See Ling Loy, Seng Bin Ang, Shang Chee Chong, Sharon Ng, Shiao-Yng Chan, Shirong Cai, Shu-E Soh, Sok Bee Lim, Stella Tsotsi, Stephen Chin-Ying Hsu, Sue-Anne Ee Shiow Toh, Suresh Anand Sadananthan, Swee Chye Quek, Varsha Gupta, Victor Samuel Rajadurai, Walter Stunkel, Wayne Cutfield, Wee Meng Han, Wei Wei Pang, Wen Lun Yuan, Yanan Zhu, Yap Seng Chong, Yin Bun Cheung, Yiong Huak Chan, and Yung Seng Lee.

Identifiers

Local EPrints ID: 447693
URI: http://eprints.soton.ac.uk/id/eprint/447693
ISSN: 0905-6157
PURE UUID: 549e7d77-1cdc-4326-bcdc-7a6badfa0e90
ORCID for Keith Godfrey: ORCID iD orcid.org/0000-0002-4643-0618

Catalogue record

Date deposited: 18 Mar 2021 17:46
Last modified: 17 Mar 2024 06:24

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Contributors

Author: Evelyn Xiu-Ling Loo
Author: Hui Xing Lau
Author: Noor Hidayatul Aini Suaini
Author: Lydia Su Yin Wong
Author: Anne Eng Neo Goh
Author: Oon Hoe Teoh
Author: Hugo van Bever
Author: Lynette Pei-Chi Shek
Author: Bee Wah Lee
Author: Kok Hian Tan
Author: Keith Godfrey ORCID iD
Author: Johan Gunnar Eriksson
Author: Yap-Seng Chong
Author: Elizabeth Huiwen Tham

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