Factors influencing treatment burden in colorectal cancer patients undergoing curative surgery – a cross sectional study
Factors influencing treatment burden in colorectal cancer patients undergoing curative surgery – a cross sectional study
Objective: To describe the severity of treatment burden in surgically treated colorectal cancer (CRC) patients and examine associations between treatment burden and demographic and clinical variables. Methods: This cross-sectional study recruited 134 patients diagnosed with Dukes’ stage A-C CRC between 2016 and 2018 who underwent curative surgery. The Patient Experience with Treatment and Self-management (PETS) questionnaire assessed treatment burden domains of ‘workload’, ‘stressors’ and ‘impact’ between 6 weeks and 18 months after primary surgery. Results: Highest scores were observed for difficulty with healthcare services (median score 33.3), physical and mental fatigue (median score 30.0) and medical information (median score 26.8). Younger age, low education level or no cohabitants were significantly associated with higher workload PETS scores (p < 0.05, 0.013, p = 0.047, respectively). Higher PETS stressors scores were significantly associated with younger age (p = 0.006), lower education level (p = 0.016), and high comorbidity (p = 0.013). Higher PETS impact scores were significantly associated with the female sex (p = 0.050), younger age (p = <0.001–0.003), lower education (p = 0.003), no cohabitants (p = 0.003), high comorbidity (p = 0.003) and cancer stage Dukes A (p = 0.004). Conclusions: A seamless and supportive healthcare system beyond hospitalisation targeting CRC subpopulations in danger of high treatment burden may improve patients’ self-management experience.
colorectal cancer, patient-reported outcome, post-discharge, supportive care, treatment burden
Husebø, Anne M.L.
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Dalen, Ingvild
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Richardson, Alison
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Bru, Edvin
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Søreide, Jon A.
1d9b3bac-ea30-4022-8336-b5816043e230
September 2021
Husebø, Anne M.L.
c4be371f-0fb6-465f-bb76-f72650fa3e14
Dalen, Ingvild
fefe59e0-8920-4d22-b40a-cff3be0a8e03
Richardson, Alison
3db30680-aa47-43a5-b54d-62d10ece17b7
Bru, Edvin
22a82d52-503a-4a6c-83af-73fbccd2a996
Søreide, Jon A.
1d9b3bac-ea30-4022-8336-b5816043e230
Husebø, Anne M.L., Dalen, Ingvild, Richardson, Alison, Bru, Edvin and Søreide, Jon A.
(2021)
Factors influencing treatment burden in colorectal cancer patients undergoing curative surgery – a cross sectional study.
European Journal of Cancer Care, 30 (5), [e13437].
(doi:10.1111/ecc.13437).
Abstract
Objective: To describe the severity of treatment burden in surgically treated colorectal cancer (CRC) patients and examine associations between treatment burden and demographic and clinical variables. Methods: This cross-sectional study recruited 134 patients diagnosed with Dukes’ stage A-C CRC between 2016 and 2018 who underwent curative surgery. The Patient Experience with Treatment and Self-management (PETS) questionnaire assessed treatment burden domains of ‘workload’, ‘stressors’ and ‘impact’ between 6 weeks and 18 months after primary surgery. Results: Highest scores were observed for difficulty with healthcare services (median score 33.3), physical and mental fatigue (median score 30.0) and medical information (median score 26.8). Younger age, low education level or no cohabitants were significantly associated with higher workload PETS scores (p < 0.05, 0.013, p = 0.047, respectively). Higher PETS stressors scores were significantly associated with younger age (p = 0.006), lower education level (p = 0.016), and high comorbidity (p = 0.013). Higher PETS impact scores were significantly associated with the female sex (p = 0.050), younger age (p = <0.001–0.003), lower education (p = 0.003), no cohabitants (p = 0.003), high comorbidity (p = 0.003) and cancer stage Dukes A (p = 0.004). Conclusions: A seamless and supportive healthcare system beyond hospitalisation targeting CRC subpopulations in danger of high treatment burden may improve patients’ self-management experience.
Text
Factors influencing treatment burden in colorectal cancer patients undergoing curative surgery – a cross sectional study
- Accepted Manuscript
More information
Accepted/In Press date: 25 February 2021
e-pub ahead of print date: 9 March 2021
Published date: September 2021
Additional Information:
Funding Information:
The study was funded by the Western Norway Regional Health Authority as part of a Post-Doctoral Research Fellowship (HV912147). The authors thank all the study participants. We also thank the study nurse Ramesh Batol Khajavi (RN, MSc.) for supporting the recruitment of patients at the outpatient clinic.
Publisher Copyright:
© 2021 The Authors. European Journal of Cancer Care published by John Wiley & Sons Ltd
Keywords:
colorectal cancer, patient-reported outcome, post-discharge, supportive care, treatment burden
Identifiers
Local EPrints ID: 447731
URI: http://eprints.soton.ac.uk/id/eprint/447731
ISSN: 0961-5423
PURE UUID: 2970dbb7-18b2-403e-839e-717749257c27
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Date deposited: 19 Mar 2021 17:30
Last modified: 17 Mar 2024 06:24
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Contributors
Author:
Anne M.L. Husebø
Author:
Ingvild Dalen
Author:
Edvin Bru
Author:
Jon A. Søreide
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