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The single use lidocaine hydrochloride 0.5 per cent w/v and phenylephrine hydrochloride 0.5 percent w/v topical spray, can it now be employed as a multi-use atomiser?

The single use lidocaine hydrochloride 0.5 per cent w/v and phenylephrine hydrochloride 0.5 percent w/v topical spray, can it now be employed as a multi-use atomiser?
The single use lidocaine hydrochloride 0.5 per cent w/v and phenylephrine hydrochloride 0.5 percent w/v topical spray, can it now be employed as a multi-use atomiser?
Objective: This study investigated the risk of contamination of lidocaine hydrochloride 5 per cent w/v and phenylephrine hydrochloride 0.5 per cent w/v topical solution after modification of the application technique.

Methods: This paper reports a prospective basic sciences study involving 22 study samples and 1 control sample of the lidocaine hydrochloride and phenylephrine hydrochloride topical anaesthetic spray. The samples were assessed for microbiological contamination after a single use on patients using a modified application technique. The modification involves keeping the nozzle (actuator) pressed down whilst withdrawing the spray to at least 30 cm (1 ft) from the patient, before releasing the nozzle (actuator) and subsequently reapplying the spray.

Results: Three of the 23 samples confirmed bacterial growth in the bottle contents, but there was no growth in any of the samples from the pump. These bacteria are considered to be contaminants.

Conclusion: There is a potential to use the lidocaine hydrochloride 5 per cent w/v and phenylephrine hydrochloride 0.5 per cent w/v topical solution as a multi-use spray by changing the actuator between patients. This would have significant beneficial cost implications without the attendant infection control risk.
Anesthetics, Local, Cross Infection, Drug Contamination, Endoscopy, Lidocaine, Phenylephrine
0022-2151
826-829
Jog, Mandar
5fb02c60-92fc-4504-9657-ef391bfb85aa
Zudovaite, Inga
86fb1528-53a5-47b3-8002-7cf115eb0652
O'Dwyer, Matthew
319861a0-7b54-4d7a-9bde-758d9ba5bd6a
Saeed, Kordo
87cb67e5-71e8-4759-bf23-2ea00ebd8b39
Singh, Tahwinder
5d536754-1698-4a5d-9208-f2bedf85c349
Jog, Mandar
5fb02c60-92fc-4504-9657-ef391bfb85aa
Zudovaite, Inga
86fb1528-53a5-47b3-8002-7cf115eb0652
O'Dwyer, Matthew
319861a0-7b54-4d7a-9bde-758d9ba5bd6a
Saeed, Kordo
87cb67e5-71e8-4759-bf23-2ea00ebd8b39
Singh, Tahwinder
5d536754-1698-4a5d-9208-f2bedf85c349

Jog, Mandar, Zudovaite, Inga, O'Dwyer, Matthew, Saeed, Kordo and Singh, Tahwinder (2020) The single use lidocaine hydrochloride 0.5 per cent w/v and phenylephrine hydrochloride 0.5 percent w/v topical spray, can it now be employed as a multi-use atomiser? The Journal of Laryngology & Otology, 134 (9), 826-829. (doi:10.1017/S0022215120001917).

Record type: Article

Abstract

Objective: This study investigated the risk of contamination of lidocaine hydrochloride 5 per cent w/v and phenylephrine hydrochloride 0.5 per cent w/v topical solution after modification of the application technique.

Methods: This paper reports a prospective basic sciences study involving 22 study samples and 1 control sample of the lidocaine hydrochloride and phenylephrine hydrochloride topical anaesthetic spray. The samples were assessed for microbiological contamination after a single use on patients using a modified application technique. The modification involves keeping the nozzle (actuator) pressed down whilst withdrawing the spray to at least 30 cm (1 ft) from the patient, before releasing the nozzle (actuator) and subsequently reapplying the spray.

Results: Three of the 23 samples confirmed bacterial growth in the bottle contents, but there was no growth in any of the samples from the pump. These bacteria are considered to be contaminants.

Conclusion: There is a potential to use the lidocaine hydrochloride 5 per cent w/v and phenylephrine hydrochloride 0.5 per cent w/v topical solution as a multi-use spray by changing the actuator between patients. This would have significant beneficial cost implications without the attendant infection control risk.

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The_single_use_Lidocaine_Hydrochloride_0.5_per_cent_w_v_and_Phenylephrine_Hydrochloride_0.5_cent_w_v_topical_spray_can_it_now_be_employed_as_a_multi_use_atomiser_ - Accepted Manuscript
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The single use Lidocaine Hydrochloride 0.5 per cent w v and Phenylephrine Hydrochloride 0.5 cent w v topical spray can it now be employed as a multi-use atomiser-
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Accepted/In Press date: 25 June 2020
e-pub ahead of print date: 17 September 2020
Published date: September 2020
Keywords: Anesthetics, Local, Cross Infection, Drug Contamination, Endoscopy, Lidocaine, Phenylephrine

Identifiers

Local EPrints ID: 447949
URI: http://eprints.soton.ac.uk/id/eprint/447949
ISSN: 0022-2151
PURE UUID: 46f6f268-ba8b-44ae-932c-0c6a57bf12fa
ORCID for Kordo Saeed: ORCID iD orcid.org/0000-0003-0123-0302

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Date deposited: 26 Mar 2021 17:32
Last modified: 17 Mar 2024 03:56

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Contributors

Author: Mandar Jog
Author: Inga Zudovaite
Author: Matthew O'Dwyer
Author: Kordo Saeed ORCID iD
Author: Tahwinder Singh

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