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The association between ADHD and the severity of COVID-19 infection

The association between ADHD and the severity of COVID-19 infection
The association between ADHD and the severity of COVID-19 infection

Objective: Patients with ADHD are at increased risk of acquiring COVID-19. The present study assessed the possibility that ADHD also increases the risk of severe COVID-19 infection. Method: We assessed 1,870 COVID-19 positive patients, aged 5 to 60 years, registered in the database of Leumit Health Services (LHS, Israel), February to -June 2020, of whom 231 with ADHD. Logistic regression analysis models evaluated the association between ADHD and the dependent variables of being symptomatic/referral to hospitalization, controlling for demographic and medical variables. Results: Age, male sex, and BMI were confirmed to be significant risk factors for increased COVID-19 severity. ADHD was found to be associated with increased severity of COVID-19 symptoms (OR = 1.81, 95% CI [1.29, 2.52], p <.05) and referral to hospitalization (OR =1.93, 95% CI [1.06, 3.51], p =.03). Conclusion: ADHD is associated with poorer outcomes in COVID-19 infection.

ADHD, COVID-19, referral to hospitalization, symptom severity
1087-0547
Merzon, Eugene
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Weiss, Margaret D.
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Cortese, Samuele
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Rotem, Ann
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Schneider, Tzipporah
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Craig, Stephanie G.
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Vinker, Shlomo
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Golan Cohen, Avivit
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Green, Ilan
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Ashkenazi, Shai
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Weizman, Abraham
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Manor, Iris
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Merzon, Eugene
611de187-6560-41ea-9854-bfad60968e01
Weiss, Margaret D.
006f04da-6616-47a7-b86a-0dafc166b9e6
Cortese, Samuele
53d4bf2c-4e0e-4c77-9385-218350560fdb
Rotem, Ann
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Schneider, Tzipporah
372fc7fc-fbba-41de-8414-596601cbf30b
Craig, Stephanie G.
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Vinker, Shlomo
18679e42-5820-4a2f-be38-d5549c431db7
Golan Cohen, Avivit
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Green, Ilan
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Ashkenazi, Shai
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Weizman, Abraham
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Manor, Iris
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Merzon, Eugene, Weiss, Margaret D., Cortese, Samuele, Rotem, Ann, Schneider, Tzipporah, Craig, Stephanie G., Vinker, Shlomo, Golan Cohen, Avivit, Green, Ilan, Ashkenazi, Shai, Weizman, Abraham and Manor, Iris (2021) The association between ADHD and the severity of COVID-19 infection. Journal of Attention Disorders. (doi:10.1177/10870547211003659).

Record type: Article

Abstract

Objective: Patients with ADHD are at increased risk of acquiring COVID-19. The present study assessed the possibility that ADHD also increases the risk of severe COVID-19 infection. Method: We assessed 1,870 COVID-19 positive patients, aged 5 to 60 years, registered in the database of Leumit Health Services (LHS, Israel), February to -June 2020, of whom 231 with ADHD. Logistic regression analysis models evaluated the association between ADHD and the dependent variables of being symptomatic/referral to hospitalization, controlling for demographic and medical variables. Results: Age, male sex, and BMI were confirmed to be significant risk factors for increased COVID-19 severity. ADHD was found to be associated with increased severity of COVID-19 symptoms (OR = 1.81, 95% CI [1.29, 2.52], p <.05) and referral to hospitalization (OR =1.93, 95% CI [1.06, 3.51], p =.03). Conclusion: ADHD is associated with poorer outcomes in COVID-19 infection.

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JAD_ADHD and COVID-19 Severity_final
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More information

e-pub ahead of print date: 2 April 2021
Published date: 2 April 2021
Additional Information: Publisher Copyright: © ©The Author(s) 2021. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
Keywords: ADHD, COVID-19, referral to hospitalization, symptom severity

Identifiers

Local EPrints ID: 448789
URI: http://eprints.soton.ac.uk/id/eprint/448789
ISSN: 1087-0547
PURE UUID: 67bab005-5568-4ce2-ac04-f43ce12cc760
ORCID for Samuele Cortese: ORCID iD orcid.org/0000-0001-5877-8075

Catalogue record

Date deposited: 05 May 2021 16:56
Last modified: 17 Mar 2024 03:37

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Contributors

Author: Eugene Merzon
Author: Margaret D. Weiss
Author: Samuele Cortese ORCID iD
Author: Ann Rotem
Author: Tzipporah Schneider
Author: Stephanie G. Craig
Author: Shlomo Vinker
Author: Avivit Golan Cohen
Author: Ilan Green
Author: Shai Ashkenazi
Author: Abraham Weizman
Author: Iris Manor

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