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The use of bioelectrical impedance analysis to predict post-operative complications in adult patients having surgery for cancer: A systematic review

The use of bioelectrical impedance analysis to predict post-operative complications in adult patients having surgery for cancer: A systematic review
The use of bioelectrical impedance analysis to predict post-operative complications in adult patients having surgery for cancer: A systematic review

BACKGROUND: Patients undergoing surgery for cancer are at particular risk of post-operative complications. The pre-operative period is an opportunity to identify and mitigate risk factors and improve outcome. Bioelectrical impedance analysis (BIA) may offer an additional means of identifying patients at risk of post-operative morbidity.

AIMS: The aim of this systematic review was to assess the use of measures and estimates of body composition determined by BIA as markers of peri-operative risk in adult patients undergoing elective surgery for cancer.

METHODS: This review was performed in accordance with the PRISMA guidelines. The electronic databases of MEDLINE, EMBASE, CINAHL, CENTRAL and the Web of Science were searched from inception. Studies of adult participants having elective surgery for cancer were included if participants underwent BIA in the peri-operative period and were assessed for post-operative complications.

RESULTS: 2578 studies were identified, of which 12 were eligible for inclusion. In total the studies report data from 1508 subjects. Five studies examined phase angle or standardized phase angle, six examined derived measures and one examined both. Eight of the 12 demonstrated an association between phase angle and/or body composition and an increased risk of post-operative complications.

CONCLUSIONS: Bioelectrical impedance analysis in the peri-operative period may be useful in predicting the risk of complications following elective cancer surgery. Phase angle more consistently demonstrates an association than derived estimates. Further high quality studies are needed and should report the raw impedance values, standardized phase angle and the equations used to derive body composition.

Bioelectrical impedance analysis, Body composition, Cancer surgery, Phase angle, Post-operative complications
0261-5614
2914-2922
Matthews, L.
81327a4c-b2a8-44f9-b5b2-fc04f856a930
Bates, A.
46ff2189-9345-45bb-bb83-c90971ccccb4
Wootton, S.A.
bf47ef35-0b33-4edb-a2b0-ceda5c475c0c
Levett, D.
1743763a-2853-4baf-affe-6152fde8d05f
Matthews, L.
81327a4c-b2a8-44f9-b5b2-fc04f856a930
Bates, A.
46ff2189-9345-45bb-bb83-c90971ccccb4
Wootton, S.A.
bf47ef35-0b33-4edb-a2b0-ceda5c475c0c
Levett, D.
1743763a-2853-4baf-affe-6152fde8d05f

Matthews, L., Bates, A., Wootton, S.A. and Levett, D. (2021) The use of bioelectrical impedance analysis to predict post-operative complications in adult patients having surgery for cancer: A systematic review. Clinical Nutrition, 40 (5), 2914-2922. (doi:10.1016/j.clnu.2021.03.008).

Record type: Article

Abstract

BACKGROUND: Patients undergoing surgery for cancer are at particular risk of post-operative complications. The pre-operative period is an opportunity to identify and mitigate risk factors and improve outcome. Bioelectrical impedance analysis (BIA) may offer an additional means of identifying patients at risk of post-operative morbidity.

AIMS: The aim of this systematic review was to assess the use of measures and estimates of body composition determined by BIA as markers of peri-operative risk in adult patients undergoing elective surgery for cancer.

METHODS: This review was performed in accordance with the PRISMA guidelines. The electronic databases of MEDLINE, EMBASE, CINAHL, CENTRAL and the Web of Science were searched from inception. Studies of adult participants having elective surgery for cancer were included if participants underwent BIA in the peri-operative period and were assessed for post-operative complications.

RESULTS: 2578 studies were identified, of which 12 were eligible for inclusion. In total the studies report data from 1508 subjects. Five studies examined phase angle or standardized phase angle, six examined derived measures and one examined both. Eight of the 12 demonstrated an association between phase angle and/or body composition and an increased risk of post-operative complications.

CONCLUSIONS: Bioelectrical impedance analysis in the peri-operative period may be useful in predicting the risk of complications following elective cancer surgery. Phase angle more consistently demonstrates an association than derived estimates. Further high quality studies are needed and should report the raw impedance values, standardized phase angle and the equations used to derive body composition.

Text
BIA SR Final Manuscript v1.8 090221 CLEAN - Accepted Manuscript
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More information

Accepted/In Press date: 4 March 2021
e-pub ahead of print date: 17 March 2021
Published date: 1 May 2021
Keywords: Bioelectrical impedance analysis, Body composition, Cancer surgery, Phase angle, Post-operative complications

Identifiers

Local EPrints ID: 449676
URI: http://eprints.soton.ac.uk/id/eprint/449676
ISSN: 0261-5614
PURE UUID: afe38ffa-9e0f-4f35-a2e8-647d01aa942c
ORCID for A. Bates: ORCID iD orcid.org/0000-0002-3614-0270

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Date deposited: 10 Jun 2021 16:32
Last modified: 12 Nov 2024 05:06

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Contributors

Author: L. Matthews
Author: A. Bates ORCID iD
Author: S.A. Wootton
Author: D. Levett

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