The University of Southampton
University of Southampton Institutional Repository
Warning ePrints Soton is experiencing an issue with some file downloads not being available. We are working hard to fix this. Please bear with us.

Smartphone-based lifestyle coaching modifies behaviours in women with subfertility or recurrent miscarriage: a randomized controlled trial: a randomized controlled trial

Smartphone-based lifestyle coaching modifies behaviours in women with subfertility or recurrent miscarriage: a randomized controlled trial: a randomized controlled trial
Smartphone-based lifestyle coaching modifies behaviours in women with subfertility or recurrent miscarriage: a randomized controlled trial: a randomized controlled trial
Research question: is an online lifestyle coaching platform more effective at modifying periconceptional behaviours than standard advice offered by the UK National Health Service (NHS)?

Design: women with subfertility or recurrent miscarriage were recruited to a two-centre randomized controlled trial. They were randomized to either the online lifestyle coaching platform Smarter Pregnancy (intervention) or periconceptional advice provided by NHS websites (control). Participants completed a lifestyle questionnaire at baseline, 6, 12, 18 and 24 weeks, and the results were used to tailor lifestyle coaching in the intervention group. At baseline, 12 and 24 weeks, composite risk scores (CRS) were calculated. A lower CRS corresponds to a healthier lifestyle.

Results: of the 400 women recruited, 262 women were randomized (131 in each arm). At 12 weeks, a reduction in CRS (includes risk score for intake of folic acid, vegetables and fruits, smoking and alcohol) was observed in the intervention versus control arms. After correcting for baseline, the difference in the CRS between intervention and control was –0.47 (95% CI –0.97 to 0.02) at 12 weeks and –0.32 (95% CI –0.82 to 0.15) at 24 weeks. A statistically significant reduction in lifestyle risk scores was found in women with a body mass index (BMI) of 25 kg/m2 or above compared with those with a BMI below 25kg/m2. The odds of being pregnant at 24 weeks was increased in the intervention versus control (OR 2.83, 95% CI 0.35 to 57.76).

Conclusions: the Smarter Pregnancy coaching platform is more effective in delivering lifestyle advice and modulating behaviours to support women with a history of subfertility or recurrent miscarriage than standard online NHS advice.
Ehealth, Lifestyle, Lifestyle coaching, Online, Periconception, Smartphone
1472-6483
111-119
Ng, Ka Ying Bonnie
869b3b2d-dd7c-407d-88aa-5db399e02b3a
Steegers-Theunissen, Régine
134c5e64-5b09-41f7-92fc-ae591a1c5527
Willemsen, Sten
9be37793-9fc5-4522-ac69-163981d162a6
Wellstead, Susan
2264823e-ae68-4976-bbf2-92da4ba21e59
Cheong, Ying
4efbba2a-3036-4dce-82f1-8b4017952c83
Macklon, Nick
d08e4844-96cf-4333-aa84-aec9b8febb42
Ng, Ka Ying Bonnie
869b3b2d-dd7c-407d-88aa-5db399e02b3a
Steegers-Theunissen, Régine
134c5e64-5b09-41f7-92fc-ae591a1c5527
Willemsen, Sten
9be37793-9fc5-4522-ac69-163981d162a6
Wellstead, Susan
2264823e-ae68-4976-bbf2-92da4ba21e59
Cheong, Ying
4efbba2a-3036-4dce-82f1-8b4017952c83
Macklon, Nick
d08e4844-96cf-4333-aa84-aec9b8febb42

Ng, Ka Ying Bonnie, Steegers-Theunissen, Régine, Willemsen, Sten, Wellstead, Susan, Cheong, Ying and Macklon, Nick (2021) Smartphone-based lifestyle coaching modifies behaviours in women with subfertility or recurrent miscarriage: a randomized controlled trial: a randomized controlled trial. Reproductive BioMedicine Online, 43 (1), 111-119. (doi:10.1016/j.rbmo.2021.04.003).

Record type: Article

Abstract

Research question: is an online lifestyle coaching platform more effective at modifying periconceptional behaviours than standard advice offered by the UK National Health Service (NHS)?

Design: women with subfertility or recurrent miscarriage were recruited to a two-centre randomized controlled trial. They were randomized to either the online lifestyle coaching platform Smarter Pregnancy (intervention) or periconceptional advice provided by NHS websites (control). Participants completed a lifestyle questionnaire at baseline, 6, 12, 18 and 24 weeks, and the results were used to tailor lifestyle coaching in the intervention group. At baseline, 12 and 24 weeks, composite risk scores (CRS) were calculated. A lower CRS corresponds to a healthier lifestyle.

Results: of the 400 women recruited, 262 women were randomized (131 in each arm). At 12 weeks, a reduction in CRS (includes risk score for intake of folic acid, vegetables and fruits, smoking and alcohol) was observed in the intervention versus control arms. After correcting for baseline, the difference in the CRS between intervention and control was –0.47 (95% CI –0.97 to 0.02) at 12 weeks and –0.32 (95% CI –0.82 to 0.15) at 24 weeks. A statistically significant reduction in lifestyle risk scores was found in women with a body mass index (BMI) of 25 kg/m2 or above compared with those with a BMI below 25kg/m2. The odds of being pregnant at 24 weeks was increased in the intervention versus control (OR 2.83, 95% CI 0.35 to 57.76).

Conclusions: the Smarter Pregnancy coaching platform is more effective in delivering lifestyle advice and modulating behaviours to support women with a history of subfertility or recurrent miscarriage than standard online NHS advice.

Text
RBMO Ng et al 2021 - Accepted Manuscript
Restricted to Repository staff only until 11 April 2022.
Request a copy
Text
RBMO Ng et al 2021 Table 1 au (1) - Accepted Manuscript
Restricted to Repository staff only until 11 April 2022.
Request a copy
Slideshow
RBMO Ng et al 2021 Figure 1 - Accepted Manuscript
Restricted to Repository staff only until 11 April 2022.
Request a copy
Image
Figure 2 - Accepted Manuscript
Download (53kB)
Image
Figure 3 - Accepted Manuscript
Download (29kB)

Show all 5 downloads.

More information

Accepted/In Press date: 6 April 2021
e-pub ahead of print date: 11 April 2021
Keywords: Ehealth, Lifestyle, Lifestyle coaching, Online, Periconception, Smartphone

Identifiers

Local EPrints ID: 449963
URI: http://eprints.soton.ac.uk/id/eprint/449963
ISSN: 1472-6483
PURE UUID: e0e0d34f-afa2-43c3-8ffe-2ecfed898ebb
ORCID for Ying Cheong: ORCID iD orcid.org/0000-0001-7687-4597

Catalogue record

Date deposited: 30 Jun 2021 16:30
Last modified: 26 Nov 2021 02:53

Export record

Altmetrics

Contributors

Author: Ka Ying Bonnie Ng
Author: Régine Steegers-Theunissen
Author: Sten Willemsen
Author: Susan Wellstead
Author: Ying Cheong ORCID iD
Author: Nick Macklon

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×