Psychological distress after subarachnoid haemorrhage: a systematic review and meta-analysis
Psychological distress after subarachnoid haemorrhage: a systematic review and meta-analysis
Objective: Psychological distress is a common complication in patients after Subarachnoid haemorrhage (SAH) which often has significant impact on the prognosis. The objective of this study was to determine the pooled prevalence of anxiety symptoms and depressive symptoms in patients after SAH and identify relevant risk factors. Methods: The study adopted a systematic review and meta-analysis protocol. Multiple databases including EMBASE, Medline, PsychInfo, and Web of Science were searched for publications before 1st January 2020. Screening, data extraction, and quality assessment were undertaken following the PRISMA guidelines for preferred reporting of systematic reviews and meta-analysis. The random-effects model was used to calculate pooled prevalence rates. Meta-analysis was conducted using Comprehensive Meta-analysis software. The review protocol was registered on PROSPERO (CRD42020182594). Results: 42 studies reporting anxiety symptoms and 64 studies reporting depressive symptoms were included. The pooled short term(<3 years) and long term(≥3 years) prevalence rates of anxiety symptoms were 31.4%(95% CI: 23.6%, 40.4%) and 40.4%(95% CI: 31.6%, 49.8%), respectively, whereas the pooled short term and long term prevalence rates of depressive symptoms were 25.2%(95%CI: 17.8%, 34.5%) and 35.8%(95%CI: 28.6%, 43.6%), respectively. Gender and pre-existing psychiatric conditions were identified as potential risk factors. Conclusions: The high prevalence of anxiety symptoms and depressive symptoms after SAH highlights the need for appropriate assessment and management of psychological stress in patients after SAH. Further research is warranted to explore potential underlying mechanisms and to develop holistic interventions that incorporate understanding of both the biological and psychological impact of SAH.
Anxiety, Depression, Meta-analysis, Subarachnoid haemorrhage, Systematic review
Bartlett, Maeve
013f7f0e-b7c2-4435-849d-f7b452680b10
Bulters, Diederik
d6f9644a-a32f-45d8-b5ed-be54486ec21d
Hou, Ruihua
470bdcbc-93a9-4dad-aac5-26d455c34376
September 2021
Bartlett, Maeve
013f7f0e-b7c2-4435-849d-f7b452680b10
Bulters, Diederik
d6f9644a-a32f-45d8-b5ed-be54486ec21d
Hou, Ruihua
470bdcbc-93a9-4dad-aac5-26d455c34376
Bartlett, Maeve, Bulters, Diederik and Hou, Ruihua
(2021)
Psychological distress after subarachnoid haemorrhage: a systematic review and meta-analysis.
Journal of Psychosomatic Research, 148, [110559].
(doi:10.1016/j.jpsychores.2021.110559).
Abstract
Objective: Psychological distress is a common complication in patients after Subarachnoid haemorrhage (SAH) which often has significant impact on the prognosis. The objective of this study was to determine the pooled prevalence of anxiety symptoms and depressive symptoms in patients after SAH and identify relevant risk factors. Methods: The study adopted a systematic review and meta-analysis protocol. Multiple databases including EMBASE, Medline, PsychInfo, and Web of Science were searched for publications before 1st January 2020. Screening, data extraction, and quality assessment were undertaken following the PRISMA guidelines for preferred reporting of systematic reviews and meta-analysis. The random-effects model was used to calculate pooled prevalence rates. Meta-analysis was conducted using Comprehensive Meta-analysis software. The review protocol was registered on PROSPERO (CRD42020182594). Results: 42 studies reporting anxiety symptoms and 64 studies reporting depressive symptoms were included. The pooled short term(<3 years) and long term(≥3 years) prevalence rates of anxiety symptoms were 31.4%(95% CI: 23.6%, 40.4%) and 40.4%(95% CI: 31.6%, 49.8%), respectively, whereas the pooled short term and long term prevalence rates of depressive symptoms were 25.2%(95%CI: 17.8%, 34.5%) and 35.8%(95%CI: 28.6%, 43.6%), respectively. Gender and pre-existing psychiatric conditions were identified as potential risk factors. Conclusions: The high prevalence of anxiety symptoms and depressive symptoms after SAH highlights the need for appropriate assessment and management of psychological stress in patients after SAH. Further research is warranted to explore potential underlying mechanisms and to develop holistic interventions that incorporate understanding of both the biological and psychological impact of SAH.
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Accepted/In Press date: 26 June 2021
e-pub ahead of print date: 4 July 2021
Published date: September 2021
Additional Information:
Funding Information:
We would like to thank Quang-Vinh Banh who acted as an independent second reviewer for screening papers using the Rayyan systematic review application during the study selection stage.
Publisher Copyright:
© 2021
Keywords:
Anxiety, Depression, Meta-analysis, Subarachnoid haemorrhage, Systematic review
Identifiers
Local EPrints ID: 450172
URI: http://eprints.soton.ac.uk/id/eprint/450172
ISSN: 0022-3999
PURE UUID: a77d675f-c22f-46bc-b1e1-89714dc5cd8a
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Date deposited: 14 Jul 2021 16:48
Last modified: 17 Mar 2024 06:41
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Contributors
Author:
Maeve Bartlett
Author:
Diederik Bulters
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