Impact of Covid-19 on health-related quality of life of patients: a structured review
Impact of Covid-19 on health-related quality of life of patients: a structured review
Introduction
Coronavirus disease (Covid-19) has led to a global pandemic since its emergence in December 2019. The majority of research into Covid-19 has focused on transmission, and mortality and morbidity associated with the virus. However, less attention has been given to its impact on health-related quality of life (HRQoL) of patients with Covid-19.
Methods
We searched for original studies published between December 2019 and Jan 2021 in PubMed, Scopus and Medline databases using a specific search strategy. We also explored literature on websites of distinguished public health organisations and hand-searched reference lists of eligible studies. The studies were screened by two reviewers according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) flowchart using pre-determined eligibility criteria. Data were synthesised, analysed descriptively and reported in line with PRISMA guidelines.
Results
In total, 1276 studies were identified through the search strategy. Of these, 77 studies were selected for full-text reading after screening the studies. After reading full-text, 12 eligible studies were included in this review. The majority of the studies used a generic HRQoL assessment tool; five studies used SF-36, five studies used EQ-5D-5L, and three used pulmonary disease-specific HRQoL tools (two studies used two tools each). The impact of Covid-19 on HRQoL was found to be considerable in both Acute Covid and Long Covid patients. Higher impact on HRQoL was reported in Acute Covid, females, older ages, patients with more severe disease and patients from low-income countries.
Conclusion
The impact of Covid-19 on HRQoL of Acute and Long Covid patients is substantial. There was disproportional impact on patients by gender, age, severity of illness and study country. The long-term impact of Covid-19 is still in its initial stage. The findings of the review may be useful to researchers, policymakers, and clinicians caring for people following Covid-19 infection.
Poudel, Ak Narayan
59433cc4-3bad-4c77-ae48-baf8c8b09681
Zhu, Shihua
13511f9c-151c-483c-9dfd-2da13421db5c
Cooper, Nicola
3cafdcda-6e1c-40a0-9b8f-5fe9a027245b
Roderick, Paul
dbb3cd11-4c51-4844-982b-0eb30ad5085a
Alwan, Nisreen
0d37b320-f325-4ed3-ba51-0fe2866d5382
Tarrant, Carolyn
c797f559-6284-4ce5-b00b-a0cb2ec09282
Ziauddeen, Nida
8b233a4a-9763-410b-90c7-df5c7d1a26e4
Yao, Guiqing Lily
93c8b843-35ee-4a63-8486-98efa85cb7f5
28 October 2021
Poudel, Ak Narayan
59433cc4-3bad-4c77-ae48-baf8c8b09681
Zhu, Shihua
13511f9c-151c-483c-9dfd-2da13421db5c
Cooper, Nicola
3cafdcda-6e1c-40a0-9b8f-5fe9a027245b
Roderick, Paul
dbb3cd11-4c51-4844-982b-0eb30ad5085a
Alwan, Nisreen
0d37b320-f325-4ed3-ba51-0fe2866d5382
Tarrant, Carolyn
c797f559-6284-4ce5-b00b-a0cb2ec09282
Ziauddeen, Nida
8b233a4a-9763-410b-90c7-df5c7d1a26e4
Yao, Guiqing Lily
93c8b843-35ee-4a63-8486-98efa85cb7f5
Poudel, Ak Narayan, Zhu, Shihua, Cooper, Nicola, Roderick, Paul, Alwan, Nisreen, Tarrant, Carolyn, Ziauddeen, Nida and Yao, Guiqing Lily
(2021)
Impact of Covid-19 on health-related quality of life of patients: a structured review.
PLoS ONE, 16 (10 October), [e0259164].
(doi:10.1371/journal.pone.0259164).
Abstract
Introduction
Coronavirus disease (Covid-19) has led to a global pandemic since its emergence in December 2019. The majority of research into Covid-19 has focused on transmission, and mortality and morbidity associated with the virus. However, less attention has been given to its impact on health-related quality of life (HRQoL) of patients with Covid-19.
Methods
We searched for original studies published between December 2019 and Jan 2021 in PubMed, Scopus and Medline databases using a specific search strategy. We also explored literature on websites of distinguished public health organisations and hand-searched reference lists of eligible studies. The studies were screened by two reviewers according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) flowchart using pre-determined eligibility criteria. Data were synthesised, analysed descriptively and reported in line with PRISMA guidelines.
Results
In total, 1276 studies were identified through the search strategy. Of these, 77 studies were selected for full-text reading after screening the studies. After reading full-text, 12 eligible studies were included in this review. The majority of the studies used a generic HRQoL assessment tool; five studies used SF-36, five studies used EQ-5D-5L, and three used pulmonary disease-specific HRQoL tools (two studies used two tools each). The impact of Covid-19 on HRQoL was found to be considerable in both Acute Covid and Long Covid patients. Higher impact on HRQoL was reported in Acute Covid, females, older ages, patients with more severe disease and patients from low-income countries.
Conclusion
The impact of Covid-19 on HRQoL of Acute and Long Covid patients is substantial. There was disproportional impact on patients by gender, age, severity of illness and study country. The long-term impact of Covid-19 is still in its initial stage. The findings of the review may be useful to researchers, policymakers, and clinicians caring for people following Covid-19 infection.
Text
PONE-D-21-10349R1_FTC_Final_Track Changes
- Accepted Manuscript
Text
journal.pone.0259164
- Version of Record
More information
Accepted/In Press date: October 2021
Published date: 28 October 2021
Additional Information:
Publisher Copyright:
© 2021 Poudel et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Identifiers
Local EPrints ID: 452498
URI: http://eprints.soton.ac.uk/id/eprint/452498
ISSN: 1932-6203
PURE UUID: 96bcfc5a-9f62-4c9b-9cfc-13d4129597b0
Catalogue record
Date deposited: 11 Dec 2021 11:21
Last modified: 17 Mar 2024 03:59
Export record
Altmetrics
Contributors
Author:
Ak Narayan Poudel
Author:
Nicola Cooper
Author:
Carolyn Tarrant
Author:
Nida Ziauddeen
Author:
Guiqing Lily Yao
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics