Longitudinal dietary trajectories from preconception to mid-childhood in women and children in the Southampton Women’s Survey and their relation to offspring adiposity: a group-based trajectory modelling approach
Longitudinal dietary trajectories from preconception to mid-childhood in women and children in the Southampton Women’s Survey and their relation to offspring adiposity: a group-based trajectory modelling approach
Background: Rates of childhood obesity are increasing globally, with poor dietary quality an important contributory factor. Evaluation of longitudinal diet quality across early life could identify timepoints and subgroups for nutritional interventions as part of effective public health strategies. Objective: This research aimed to: (1) define latent classes of mother-offspring diet quality trajectories from pre-pregnancy to child age 8–9 years, (2) identify early life factors associated with these trajectories, and (3) describe the association between the trajectories and childhood adiposity outcomes. Design: Dietary data from 2963 UK Southampton Women’s Survey mother-offspring dyads were analysed using group-based trajectory modelling of a diet quality index (DQI). Maternal diet was assessed pre-pregnancy and at 11- and 34-weeks’ gestation, and offspring diet at ages 6 and 12 months, 3, 6-7- and 8–9-years using interviewer-administered food frequency questionnaires. At each timepoint, a standardised DQI was derived using principal component analysis. Adiposity age 8–9 years was assessed using dual-energy X-ray absorptiometry (DXA) and BMI z-scores. Results: A five-trajectory group model was identified as optimal. The diet quality trajectories were characterised as stable, horizontal lines and were categorised as poor (n = 142), poor-medium (n = 667), medium (n = 1146), medium-better (n = 818) and best (n = 163). A poorer dietary trajectory was associated with higher maternal pre-pregnancy BMI, smoking, multiparity, lower maternal age and lower educational attainment. Using linear regression adjusted for confounders, a 1-category decrease in the dietary trajectory was associated with higher DXA percentage body fat (0.08 SD (95% confidence interval 0.01, 0.15) and BMI z-score (0.08 SD (0.00, 0.16) in the 1216 children followed up at age 8–9 years. Conclusion: Mother-offspring dietary trajectories are stable across early life, with poorer diet quality associated with maternal socio-demographic and other factors and childhood adiposity. The preconception period may be an important window to promote positive maternal dietary changes in order to improve childhood outcomes.
Dalrymple, Kathryn V.
8ef94198-4e90-44a9-b77d-19d35d013cde
Vogel, Christina
768f1dcd-2697-4aae-95cc-ee2f6d63dff5
Godfrey, Keith
0931701e-fe2c-44b5-8f0d-ec5c7477a6fd
Baird, Janis
f4bf2039-6118-436f-ab69-df8b4d17f824
Harvey, Nicholas
ce487fb4-d360-4aac-9d17-9466d6cba145
Hanson, Mark
1952fad1-abc7-4284-a0bc-a7eb31f70a3f
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Inskip, Hazel
5fb4470a-9379-49b2-a533-9da8e61058b7
Crozier, Sarah
9c3595ce-45b0-44fa-8c4c-4c555e628a03
16 December 2021
Dalrymple, Kathryn V.
8ef94198-4e90-44a9-b77d-19d35d013cde
Vogel, Christina
768f1dcd-2697-4aae-95cc-ee2f6d63dff5
Godfrey, Keith
0931701e-fe2c-44b5-8f0d-ec5c7477a6fd
Baird, Janis
f4bf2039-6118-436f-ab69-df8b4d17f824
Harvey, Nicholas
ce487fb4-d360-4aac-9d17-9466d6cba145
Hanson, Mark
1952fad1-abc7-4284-a0bc-a7eb31f70a3f
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Inskip, Hazel
5fb4470a-9379-49b2-a533-9da8e61058b7
Crozier, Sarah
9c3595ce-45b0-44fa-8c4c-4c555e628a03
Dalrymple, Kathryn V., Vogel, Christina, Godfrey, Keith, Baird, Janis, Harvey, Nicholas, Hanson, Mark, Cooper, Cyrus, Inskip, Hazel and Crozier, Sarah
(2021)
Longitudinal dietary trajectories from preconception to mid-childhood in women and children in the Southampton Women’s Survey and their relation to offspring adiposity: a group-based trajectory modelling approach.
International Journal of Obesity.
(doi:10.1038/s41366-021-01047-2).
Abstract
Background: Rates of childhood obesity are increasing globally, with poor dietary quality an important contributory factor. Evaluation of longitudinal diet quality across early life could identify timepoints and subgroups for nutritional interventions as part of effective public health strategies. Objective: This research aimed to: (1) define latent classes of mother-offspring diet quality trajectories from pre-pregnancy to child age 8–9 years, (2) identify early life factors associated with these trajectories, and (3) describe the association between the trajectories and childhood adiposity outcomes. Design: Dietary data from 2963 UK Southampton Women’s Survey mother-offspring dyads were analysed using group-based trajectory modelling of a diet quality index (DQI). Maternal diet was assessed pre-pregnancy and at 11- and 34-weeks’ gestation, and offspring diet at ages 6 and 12 months, 3, 6-7- and 8–9-years using interviewer-administered food frequency questionnaires. At each timepoint, a standardised DQI was derived using principal component analysis. Adiposity age 8–9 years was assessed using dual-energy X-ray absorptiometry (DXA) and BMI z-scores. Results: A five-trajectory group model was identified as optimal. The diet quality trajectories were characterised as stable, horizontal lines and were categorised as poor (n = 142), poor-medium (n = 667), medium (n = 1146), medium-better (n = 818) and best (n = 163). A poorer dietary trajectory was associated with higher maternal pre-pregnancy BMI, smoking, multiparity, lower maternal age and lower educational attainment. Using linear regression adjusted for confounders, a 1-category decrease in the dietary trajectory was associated with higher DXA percentage body fat (0.08 SD (95% confidence interval 0.01, 0.15) and BMI z-score (0.08 SD (0.00, 0.16) in the 1216 children followed up at age 8–9 years. Conclusion: Mother-offspring dietary trajectories are stable across early life, with poorer diet quality associated with maternal socio-demographic and other factors and childhood adiposity. The preconception period may be an important window to promote positive maternal dietary changes in order to improve childhood outcomes.
Text
article_file (002)
- Accepted Manuscript
More information
Accepted/In Press date: 22 November 2021
e-pub ahead of print date: 16 December 2021
Published date: 16 December 2021
Additional Information:
Funding Information:
We are grateful to the women of Southampton and their children who took part in these studies and the research nurses and other staff who collected and processed the data. KVD is funded by the MRC (grant number: MR/V005839/1). This work from the SWS was supported by grants from the Medical Research Council (MC_UU_12011/4), National Institute for Health Research Southampton Biomedical Research Centre, the University of Southampton and University Hospital Southampton National Health Service Foundation Trust, the European Union’s Seventh Framework Programme (FP7/2007-2013), project EarlyNutrition (grant 289346) and European Union’s Horizon 2020 research and innovation programme under grant agreement No 733206 (LifeCycle). KMG is supported by the National Institute for Health Research (NIHR Senior Investigator (NF-SI-0515-10042) and the NIHR Southampton Biomedical Research Centre) and the European Union (Erasmus + Programme ImpENSA 598488-EPP-1-2018-1-DE-EPPKA2-CBHE-JP) and KMG and MAH by the British Heart Foundation (RG/15/17/3174). Study participants were drawn from a cohort study funded by the Medical Research Council and the Dunhill Medical Trust.
Publisher Copyright:
© 2021, The Author(s).
Identifiers
Local EPrints ID: 453309
URI: http://eprints.soton.ac.uk/id/eprint/453309
ISSN: 0307-0565
PURE UUID: 94282226-099e-4489-b18d-1ef240dd5e4d
Catalogue record
Date deposited: 12 Jan 2022 17:40
Last modified: 18 Mar 2024 05:10
Export record
Altmetrics
Contributors
Author:
Kathryn V. Dalrymple
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
