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Minimising Young Children’s Anxiety through Schools (MY-CATS): Protocol for a cluster randomised controlled trial to evaluate the effectiveness and cost-effectiveness of an online parent-led intervention compared with usual school practice for young children identified as at-risk for anxiety disorders

Minimising Young Children’s Anxiety through Schools (MY-CATS): Protocol for a cluster randomised controlled trial to evaluate the effectiveness and cost-effectiveness of an online parent-led intervention compared with usual school practice for young children identified as at-risk for anxiety disorders
Minimising Young Children’s Anxiety through Schools (MY-CATS): Protocol for a cluster randomised controlled trial to evaluate the effectiveness and cost-effectiveness of an online parent-led intervention compared with usual school practice for young children identified as at-risk for anxiety disorders
Background: identifying and supporting young children who are at-risk of developing anxiety disorders would benefit children, families, and wider society. Elevated anxiety symptoms, inhibited temperament, and high parental anxiety are established risk factors for later anxiety disorders, but it remains unclear who is most likely to benefit from prevention and early intervention programmes. Delivering an online intervention through schools to parents of young children who have one or more of these risks could maximise reach.

The primary aim of this trial is to evaluate the effectiveness and cost-effectiveness of delivering an online parent-led intervention, compared with usual school provision only, for children (aged 4-7) identified as at-risk for anxiety disorders on the basis of at least one risk factor. We also aim to identify the characteristics of children who do and do not benefit from intervention and mechanisms of change from the intervention.

Methods: the design will be a parallel group, superiority cluster randomised controlled trial, with schools (clusters) randomised to intervention or usual school practice arms in a 1:1 ratio stratified according to level of deprivation within the school. The study will recruit and randomise at least 60 primary/infant schools in England, and on the basis of recruiting 60 schools, we will recruit 1080 trial participants (540 per arm). Parents of all children (aged 4-7) in sampled Reception, Year 1, and Year 2 classes will be invited to complete screening questionnaires. Children who screen positive on the basis of anxiety symptoms, and/or behavioural inhibition, and/or parent anxiety symptoms will be eligible for the trial. Parents/carers of children in schools allocated to the intervention arm will be offered a brief online intervention; schools in both arms will continue to provide any usual support for children and parents throughout the trial. Assessments will be completed at: screening, baseline (before randomisation), 6-weeks, 12-weeks, and 12-months post randomisation. The primary outcome will be the absence/presence of an anxiety disorder diagnosis at 12-months.

Discussion: the trial will determine if delivering an online intervention for parents of young children at-risk of anxiety disorders identified through screening in schools is effective and cost-effective.

ISRCTN: 82398107
anxiety, children, prevention, early intervention, screening, schools, at risk, online intervention, parent-led intervention, cost-effectiveness
1745-6215
Research Square
Reardon, Tessa
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Dodd, Helen
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Hill, Claire
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Jasper, Bec
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Lawrence, Peter
0d45e107-38ef-4932-aec1-504573de01ef
Morgan, Fran
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Rapee, Ronald M.
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Ukoumunne, Obioha
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Violato, Mara
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Davey, Emily
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Halliday, Gemma
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Jones, Benjamin
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Martineau, Lindsey
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McCall, Amy
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Niekamp, Natascha
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Placzek, Anna
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Potts, Ruth
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Weisser, Tamatha
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Creswell, Cathy
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Reardon, Tessa
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Dodd, Helen
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Hill, Claire
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Jasper, Bec
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Lawrence, Peter
0d45e107-38ef-4932-aec1-504573de01ef
Morgan, Fran
03dfd5f4-a48b-4724-83c1-3eb56e5fe09b
Rapee, Ronald M.
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Ukoumunne, Obioha
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Violato, Mara
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Davey, Emily
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Halliday, Gemma
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Jones, Benjamin
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Martineau, Lindsey
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McCall, Amy
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Niekamp, Natascha
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Placzek, Anna
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Potts, Ruth
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Weisser, Tamatha
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Creswell, Cathy
62d7d30e-b718-4985-87b1-33ed4360a969

[Unknown type: UNSPECIFIED]

Record type: UNSPECIFIED

Abstract

Background: identifying and supporting young children who are at-risk of developing anxiety disorders would benefit children, families, and wider society. Elevated anxiety symptoms, inhibited temperament, and high parental anxiety are established risk factors for later anxiety disorders, but it remains unclear who is most likely to benefit from prevention and early intervention programmes. Delivering an online intervention through schools to parents of young children who have one or more of these risks could maximise reach.

The primary aim of this trial is to evaluate the effectiveness and cost-effectiveness of delivering an online parent-led intervention, compared with usual school provision only, for children (aged 4-7) identified as at-risk for anxiety disorders on the basis of at least one risk factor. We also aim to identify the characteristics of children who do and do not benefit from intervention and mechanisms of change from the intervention.

Methods: the design will be a parallel group, superiority cluster randomised controlled trial, with schools (clusters) randomised to intervention or usual school practice arms in a 1:1 ratio stratified according to level of deprivation within the school. The study will recruit and randomise at least 60 primary/infant schools in England, and on the basis of recruiting 60 schools, we will recruit 1080 trial participants (540 per arm). Parents of all children (aged 4-7) in sampled Reception, Year 1, and Year 2 classes will be invited to complete screening questionnaires. Children who screen positive on the basis of anxiety symptoms, and/or behavioural inhibition, and/or parent anxiety symptoms will be eligible for the trial. Parents/carers of children in schools allocated to the intervention arm will be offered a brief online intervention; schools in both arms will continue to provide any usual support for children and parents throughout the trial. Assessments will be completed at: screening, baseline (before randomisation), 6-weeks, 12-weeks, and 12-months post randomisation. The primary outcome will be the absence/presence of an anxiety disorder diagnosis at 12-months.

Discussion: the trial will determine if delivering an online intervention for parents of young children at-risk of anxiety disorders identified through screening in schools is effective and cost-effective.

ISRCTN: 82398107

Text
MYCATS protocol 13.10.2021 - Accepted Manuscript
Available under License Creative Commons Attribution.
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More information

Published date: 10 January 2022
Additional Information: This project is funded by the Kavli Trust. The funder has not contributed to the study design; collection, management, analysis, and interpretation of data; writing of reports; or the decision to submit reports for publication. CC is supported by the Oxford and Thames Valley National Institute for Health Research Applied Research Collaboration. HD is funded by a UKRI Future Leaders Fellowship MR/S017909/1. OU and BJo are supported by the National Institute for Health Research Applied Research Collaboration South West Peninsula. MV is partly supported by the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC) and receives funding from the National Institute for Health Research (NIHR) Applied Research Collaboration Oxford and Thames Valley at Oxford Health NHS Foundation Trust. The views expressed are those of the authors and not necessarily those of the NHS, NIHR or the Department of Health and Social Care.
Keywords: anxiety, children, prevention, early intervention, screening, schools, at risk, online intervention, parent-led intervention, cost-effectiveness

Identifiers

Local EPrints ID: 454361
URI: http://eprints.soton.ac.uk/id/eprint/454361
ISSN: 1745-6215
PURE UUID: e30f2225-82c5-4793-9bbb-fbd7a3bcd65f
ORCID for Peter Lawrence: ORCID iD orcid.org/0000-0001-6181-433X

Catalogue record

Date deposited: 08 Feb 2022 17:34
Last modified: 17 Mar 2024 03:34

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Contributors

Author: Tessa Reardon
Author: Helen Dodd
Author: Claire Hill
Author: Bec Jasper
Author: Peter Lawrence ORCID iD
Author: Fran Morgan
Author: Ronald M. Rapee
Author: Obioha Ukoumunne
Author: Mara Violato
Author: Emily Davey
Author: Gemma Halliday
Author: Benjamin Jones
Author: Lindsey Martineau
Author: Amy McCall
Author: Natascha Niekamp
Author: Anna Placzek
Author: Ruth Potts
Author: Tamatha Weisser
Author: Cathy Creswell

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