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Patient preferences for lifestyle behaviours in osteoporotic fracture prevention: a cross-European discrete choice experiment

Patient preferences for lifestyle behaviours in osteoporotic fracture prevention: a cross-European discrete choice experiment
Patient preferences for lifestyle behaviours in osteoporotic fracture prevention: a cross-European discrete choice experiment
Summary: using a discrete choice experiment, we aimed to assess patients’ preferences with regard to adopting lifestyle behaviours to prevent osteoporotic fractures. Overall, the 1042 patients recruited from seven European countries were favourable to some lifestyle behaviours (i.e., engaging in moderate physical activity, taking calcium and vitamin D supplements, reducing their alcohol consumption and ensuring a normal body weight).

Introduction: alongside medical therapy, healthy lifestyle habits are recommended for preventing osteoporotic fractures. In this study, we aimed to assess patients’ preferences with regard to adopting lifestyle changes to prevent osteoporotic fractures.

Methods: a discrete choice experiment was conducted in seven European countries. Patients with or at risk of osteoporosis were asked to indicate to what extent they would be motivated to adhere to 16 lifestyle packages that differed in various levels of 6 attributes. The attributes and levels proposed were physical activity (levels: not included, moderate or high), calcium and vitamin D status (levels: not included, taking supplements, improving nutrition and assuring a minimal exposure to sunlight daily), smoking (levels: not included, quit smoking), alcohol (levels: not included, moderate consumption), weight reduction (levels: not included, ensure a healthy body weight) and fall prevention (levels: not included, receiving general advice or following a 1-day fall prevention program). A conditional logit model was used to estimate a patient’s relative preferences for the various attributes across all participants and per country.

Results: in total, 1042 patients completed the questionnaire. Overall, patients were favourable to lifestyle behaviours for preventing osteoporotic fractures. However, among the lifestyle behaviours proposed, patients were consensually not prone to engage in a high level of physical activity. In addition, in Ireland, Belgium, the Netherlands and Switzerland, patients were also not inclined to participate in a 1-day fall prevention program and Belgian, Swiss and Dutch patients were not prone to adhere to a well-balanced nutritional program. Nevertheless, we observed globally that patients felt positively about reducing their alcohol consumption, engaging in moderate physical activity, taking calcium and vitamin D supplements and ensuring a normal body weight, all measures aimed at preventing fractures.

Conclusions: in a patient-centred approach, fracture prevention should take these considerations and preferences into account.
Discrete choice experiment, Fractures, Lifestyle, Osteoporosis, Patients’ preferences
0937-941X
1335-1346
Beaudart, Charlotte
bdc9da98-791a-474b-9745-be0695a4d8a9
Boonen, Annelies
c32bd0a4-48b2-45f9-9ab3-5ff0074b7f32
Li, Nannan
391359b5-57f5-4c82-ac68-888a6a1eb36f
Bours, Sandrine
e0b3a710-883f-4e13-a0ad-834ac8129201
Goemeare, Stefan
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Reginster, Jean Yves
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Roux, Christian
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McGowan, Bernie
cbda2b75-7701-4b41-8c4c-497d3edfcbc9
Diez-Pérez, A.
19f89c53-003a-469c-92ac-69b0b979f3ec
Rizzoli, Rene
e02c0d92-6da1-430c-a669-0c20e94a850a
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Hiligsmann, Mickaël
120a5b99-2a0a-4a17-99d1-c0e5147d4f59
Beaudart, Charlotte
bdc9da98-791a-474b-9745-be0695a4d8a9
Boonen, Annelies
c32bd0a4-48b2-45f9-9ab3-5ff0074b7f32
Li, Nannan
391359b5-57f5-4c82-ac68-888a6a1eb36f
Bours, Sandrine
e0b3a710-883f-4e13-a0ad-834ac8129201
Goemeare, Stefan
36fcdcaa-cff4-4986-9106-3e46b63c9d1e
Reginster, Jean Yves
33684a35-87f7-4b8d-bb91-4da2b809f855
Roux, Christian
1f852839-8036-423f-ade1-a003d42271fa
McGowan, Bernie
cbda2b75-7701-4b41-8c4c-497d3edfcbc9
Diez-Pérez, A.
19f89c53-003a-469c-92ac-69b0b979f3ec
Rizzoli, Rene
e02c0d92-6da1-430c-a669-0c20e94a850a
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Hiligsmann, Mickaël
120a5b99-2a0a-4a17-99d1-c0e5147d4f59

Beaudart, Charlotte, Boonen, Annelies, Li, Nannan, Bours, Sandrine, Goemeare, Stefan, Reginster, Jean Yves, Roux, Christian, McGowan, Bernie, Diez-Pérez, A., Rizzoli, Rene, Cooper, Cyrus and Hiligsmann, Mickaël (2022) Patient preferences for lifestyle behaviours in osteoporotic fracture prevention: a cross-European discrete choice experiment. Osteoporosis International, 33 (6), 1335-1346. (doi:10.1007/s00198-022-06310-4).

Record type: Article

Abstract

Summary: using a discrete choice experiment, we aimed to assess patients’ preferences with regard to adopting lifestyle behaviours to prevent osteoporotic fractures. Overall, the 1042 patients recruited from seven European countries were favourable to some lifestyle behaviours (i.e., engaging in moderate physical activity, taking calcium and vitamin D supplements, reducing their alcohol consumption and ensuring a normal body weight).

Introduction: alongside medical therapy, healthy lifestyle habits are recommended for preventing osteoporotic fractures. In this study, we aimed to assess patients’ preferences with regard to adopting lifestyle changes to prevent osteoporotic fractures.

Methods: a discrete choice experiment was conducted in seven European countries. Patients with or at risk of osteoporosis were asked to indicate to what extent they would be motivated to adhere to 16 lifestyle packages that differed in various levels of 6 attributes. The attributes and levels proposed were physical activity (levels: not included, moderate or high), calcium and vitamin D status (levels: not included, taking supplements, improving nutrition and assuring a minimal exposure to sunlight daily), smoking (levels: not included, quit smoking), alcohol (levels: not included, moderate consumption), weight reduction (levels: not included, ensure a healthy body weight) and fall prevention (levels: not included, receiving general advice or following a 1-day fall prevention program). A conditional logit model was used to estimate a patient’s relative preferences for the various attributes across all participants and per country.

Results: in total, 1042 patients completed the questionnaire. Overall, patients were favourable to lifestyle behaviours for preventing osteoporotic fractures. However, among the lifestyle behaviours proposed, patients were consensually not prone to engage in a high level of physical activity. In addition, in Ireland, Belgium, the Netherlands and Switzerland, patients were also not inclined to participate in a 1-day fall prevention program and Belgian, Swiss and Dutch patients were not prone to adhere to a well-balanced nutritional program. Nevertheless, we observed globally that patients felt positively about reducing their alcohol consumption, engaging in moderate physical activity, taking calcium and vitamin D supplements and ensuring a normal body weight, all measures aimed at preventing fractures.

Conclusions: in a patient-centred approach, fracture prevention should take these considerations and preferences into account.

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Accepted/In Press date: 12 January 2022
e-pub ahead of print date: 22 January 2022
Keywords: Discrete choice experiment, Fractures, Lifestyle, Osteoporosis, Patients’ preferences

Identifiers

Local EPrints ID: 454686
URI: http://eprints.soton.ac.uk/id/eprint/454686
ISSN: 0937-941X
PURE UUID: 7cf9f83a-6080-481b-adaa-8b1bf3da7b25
ORCID for Cyrus Cooper: ORCID iD orcid.org/0000-0003-3510-0709

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Date deposited: 21 Feb 2022 17:34
Last modified: 24 Jul 2022 01:35

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Contributors

Author: Charlotte Beaudart
Author: Annelies Boonen
Author: Nannan Li
Author: Sandrine Bours
Author: Stefan Goemeare
Author: Jean Yves Reginster
Author: Christian Roux
Author: Bernie McGowan
Author: A. Diez-Pérez
Author: Rene Rizzoli
Author: Cyrus Cooper ORCID iD
Author: Mickaël Hiligsmann

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