Heijtz, Rochellys Diaz, Gressens, Pierre and Swann, Jonathan R. (2022) Targeting microbial metabolites to treat autism. Nature Medicine, 28 (3), 448-450. (doi:10.1038/s41591-022-01711-8).
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Article
Abstract
A first-in-class therapeutic that targets neuroactive microbial metabolites in the gut shows promising target engagement, safety and behavioral improvements in adolescents with autism spectrum disorder.
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e-pub ahead of print date: 14 February 2022
Published date: March 2022
Additional Information:
Funding Information:
R.D.H. is supported by the Swedish Research Council, the Swedish Brain Foundation, the Frimurare Barnhus Foundation and the European Union (ITN SmartAge, grant agreement number 859890). P.G. is supported by Inserm, the Université de Paris, the Horizon 2020 Framework Program of the European Union (grant agreement no. 874721/PREMSTEM), the ANR, the Fondation Grace de Monaco, the Fondation des Gueules Cassées and an additional grant from “Investissement d’Avenir-ANR-11-INBS-0011”–NeurATRIS. J.R.S. is supported by the National Institute for Health Research Southampton Biomedical Research Centre, Biotechnology and Biological Sciences Research Council (BB/W00139X/1) and Medical Research Council (MR/W003597/1).
Copyright:
Copyright 2022 Elsevier B.V., All rights reserved.
Identifiers
Local EPrints ID: 455170
URI: http://eprints.soton.ac.uk/id/eprint/455170
ISSN: 1078-8956
PURE UUID: c078e950-40a7-4090-9034-4a068c045fbd
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Date deposited: 11 Mar 2022 17:31
Last modified: 17 Mar 2024 04:00
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Contributors
Author:
Rochellys Diaz Heijtz
Author:
Pierre Gressens
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