Predictors of resilience in older adults with lower limb osteoarthritis and persistent severe pain
Predictors of resilience in older adults with lower limb osteoarthritis and persistent severe pain
Background: resilience refers to the process in which people function well despite adversity. Persistent severe pain may be considered an adversity in people with lower limb osteoarthritis (LLOA). The objectives of this study are: (1) to identify what proportion of older adults with LLOA and persistent severe pain show good functioning; and (2) to explore predictors of resilience.
Methods: data from the European Project on OSteoArthritis (EPOSA) were used involving standardized data from six European population-based cohort studies. LLOA is defined as clinical knee and/or hip osteoarthritis. Persistent severe pain is defined as the highest tertile of the pain subscale of the Western Ontario and McMaster Universities Osteoarthritis Index both at baseline and follow-up. Resilience is defined as good physical, mental or social functioning at follow-up despite having LLOA with persistent severe pain.
Results: in total, 95 (14.9%) out of 638 individuals with LLOA had persistent severe pain. Among these, 10 (11.0%), 54 (57.4%) and 49 (53.8%) had good physical, mental and social functioning, respectively. Only 4 individuals (4.5%) were resilient in all three domains of functioning. Younger age, male sex, higher education, higher mastery, smoking and alcohol use, higher physical activity levels, absence of chronic diseases, and more contacts with friends predicted resilience in one or more domains of functioning.
Conclusions: few people with LLOA and persistent severe pain showed good physical functioning and about half showed good mental or social functioning. Predictors of resilience differed between domains, and might provide new insights for treatment.
Older Adults, Osteoarthritis, Pain, Predictors, Resilience
van Schoor, Natasja M.
3a59a196-b132-414f-81de-2ad3b21f7a74
Timmermans, Erik J.
0ebf8273-3f05-4925-bb79-f7db1b55dd29
Huisman, Martijn
185f06fe-e5b0-4744-bd1f-abbb00c10663
Gutierrez-Misis, Alicia
782b83b8-99c0-4603-a00d-5c0b134581ad
Lems, Willem
f0be4806-b998-4e2e-b65b-5e8343656d83
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
Castell, Maria Victoria
7d2663d6-552c-47b8-ae98-5c1f5fdb9380
Denkinger, Michael D.
f4e6f411-bc01-4cdd-ba76-eb951d43ad16
Pedersen, Nancy L.
22ca166b-d76d-401c-be51-a81c86bc1f4a
Maggi, Stefania
57e7e62a-b7dd-4291-82e3-efc8c9a7e12a
Deeg, Dorly J.H.
09f588f6-3441-4d48-a7ff-26b4b21ebac2
24 March 2022
van Schoor, Natasja M.
3a59a196-b132-414f-81de-2ad3b21f7a74
Timmermans, Erik J.
0ebf8273-3f05-4925-bb79-f7db1b55dd29
Huisman, Martijn
185f06fe-e5b0-4744-bd1f-abbb00c10663
Gutierrez-Misis, Alicia
782b83b8-99c0-4603-a00d-5c0b134581ad
Lems, Willem
f0be4806-b998-4e2e-b65b-5e8343656d83
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
Castell, Maria Victoria
7d2663d6-552c-47b8-ae98-5c1f5fdb9380
Denkinger, Michael D.
f4e6f411-bc01-4cdd-ba76-eb951d43ad16
Pedersen, Nancy L.
22ca166b-d76d-401c-be51-a81c86bc1f4a
Maggi, Stefania
57e7e62a-b7dd-4291-82e3-efc8c9a7e12a
Deeg, Dorly J.H.
09f588f6-3441-4d48-a7ff-26b4b21ebac2
van Schoor, Natasja M., Timmermans, Erik J., Huisman, Martijn, Gutierrez-Misis, Alicia, Lems, Willem, Dennison, Elaine, Castell, Maria Victoria, Denkinger, Michael D., Pedersen, Nancy L., Maggi, Stefania and Deeg, Dorly J.H.
(2022)
Predictors of resilience in older adults with lower limb osteoarthritis and persistent severe pain.
BMC Geriatrics, 22 (1), [246].
(doi:10.1186/s12877-022-02926-7).
Abstract
Background: resilience refers to the process in which people function well despite adversity. Persistent severe pain may be considered an adversity in people with lower limb osteoarthritis (LLOA). The objectives of this study are: (1) to identify what proportion of older adults with LLOA and persistent severe pain show good functioning; and (2) to explore predictors of resilience.
Methods: data from the European Project on OSteoArthritis (EPOSA) were used involving standardized data from six European population-based cohort studies. LLOA is defined as clinical knee and/or hip osteoarthritis. Persistent severe pain is defined as the highest tertile of the pain subscale of the Western Ontario and McMaster Universities Osteoarthritis Index both at baseline and follow-up. Resilience is defined as good physical, mental or social functioning at follow-up despite having LLOA with persistent severe pain.
Results: in total, 95 (14.9%) out of 638 individuals with LLOA had persistent severe pain. Among these, 10 (11.0%), 54 (57.4%) and 49 (53.8%) had good physical, mental and social functioning, respectively. Only 4 individuals (4.5%) were resilient in all three domains of functioning. Younger age, male sex, higher education, higher mastery, smoking and alcohol use, higher physical activity levels, absence of chronic diseases, and more contacts with friends predicted resilience in one or more domains of functioning.
Conclusions: few people with LLOA and persistent severe pain showed good physical functioning and about half showed good mental or social functioning. Predictors of resilience differed between domains, and might provide new insights for treatment.
Text
Paper OA resilience final
- Accepted Manuscript
Text
s12877-022-02926-7
- Version of Record
More information
Accepted/In Press date: 7 March 2022
e-pub ahead of print date: 24 March 2022
Published date: 24 March 2022
Additional Information:
Funding Information:
The Indicators for Monitoring COPD and Asthma—Activity and Function in the Elderly in Ulm study (IMCA—ActiFE) was supported by the European Union (grant number 2005121) and the Ministry of Science, Baden-Württemberg. The Italian cohort was supported by the National Research Council of Italy (CNR), Research Project “Aging: molecular and technological innovations for improving the health of the elderly population” (Prot. MIUR 2867). The Longitudinal Aging Study Amsterdam (LASA) is financially supported by the Dutch Ministry of Health, Welfare and Sports (grant number 311669). The Peñagrande study was partially supported by the National Fund for Health Research (Fondo de Investigaciones en Salud) of Spain (grant numbers FIS PI 05/1898, FIS RETICEF RD06/0013/1013, FIS PS09/02143). The Swedish Twin Registry is managed by Karolinska Institutet and receives funding through the Swedish Research Council (grant number 2017–00641). The Hertfordshire Cohort Study is supported by the Medical Research Council of Great Britain, Versus Arthritis, the British Heart Foundation and the International Osteoporosis Foundation (grant number MRC_MC_UP_A620_1014). The funders were not involved in the study design, data collection, analysis and interpretation of data; in the writing of the manuscript; and in the decision to submit the manuscript for publication.
Publisher Copyright:
© 2022, The Author(s).
Keywords:
Older Adults, Osteoarthritis, Pain, Predictors, Resilience
Identifiers
Local EPrints ID: 455838
URI: http://eprints.soton.ac.uk/id/eprint/455838
ISSN: 1471-2318
PURE UUID: 3b7aed6a-e0c5-4082-bcf3-660835e9bd2a
Catalogue record
Date deposited: 06 Apr 2022 16:40
Last modified: 17 Mar 2024 02:43
Export record
Altmetrics
Contributors
Author:
Natasja M. van Schoor
Author:
Erik J. Timmermans
Author:
Martijn Huisman
Author:
Alicia Gutierrez-Misis
Author:
Willem Lems
Author:
Maria Victoria Castell
Author:
Michael D. Denkinger
Author:
Nancy L. Pedersen
Author:
Stefania Maggi
Author:
Dorly J.H. Deeg
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
