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Applying control algorithms to acoustofluidic particle manipulation

Applying control algorithms to acoustofluidic particle manipulation
Applying control algorithms to acoustofluidic particle manipulation
In recent years, manipulating micro particles and cells using acoustic waves has experienced significant growth in association with the latest developments of Lap-on-Chip devices. As a result, many scientific fields such as analytical chemistry have relevant applications for particle manipulation. There are many possible areas where particle manipulation can be used, for example, bringing cells to a specific position for observation and analysis. Traditionally, several techniques and methods have been employed for positioning micro particles using ultrasonic waves. However, none of these methods have demonstrated a precise positioning of particles using an automatic feedback control system using a sensor, actuator and controller. The achievement of shifting and positioning particles automatically using lateral acoustic radiation forces is the specific objective of this project where two different control algorithms (navigation and steering) have been explored. Two main acoustofluidic devices have been employed as examples. Both algorithms are based on a feedback loop which considers the direction and distance to the target at each step and then applying a chosen acoustic force. The methods rely on using two resonant frequencies: the first one is the acoustic half-wave resonance frequency that functions to levitate the particles at the half-height of the device using the axial radiation force; the second resonance frequency is chosen from a set of possible resonances, and functions to shift levitated particles in the required direction.
University of Southampton
Shaglwf, Zaid
b63f055d-ef24-4fe3-ae04-0e7b24f0f020
Shaglwf, Zaid
b63f055d-ef24-4fe3-ae04-0e7b24f0f020
Glynne-Jones, Peter
6ca3fcbc-14db-4af9-83e2-cf7c8b91ef0d

Shaglwf, Zaid (2019) Applying control algorithms to acoustofluidic particle manipulation. University of Southampton, Doctoral Thesis, 211pp.

Record type: Thesis (Doctoral)

Abstract

In recent years, manipulating micro particles and cells using acoustic waves has experienced significant growth in association with the latest developments of Lap-on-Chip devices. As a result, many scientific fields such as analytical chemistry have relevant applications for particle manipulation. There are many possible areas where particle manipulation can be used, for example, bringing cells to a specific position for observation and analysis. Traditionally, several techniques and methods have been employed for positioning micro particles using ultrasonic waves. However, none of these methods have demonstrated a precise positioning of particles using an automatic feedback control system using a sensor, actuator and controller. The achievement of shifting and positioning particles automatically using lateral acoustic radiation forces is the specific objective of this project where two different control algorithms (navigation and steering) have been explored. Two main acoustofluidic devices have been employed as examples. Both algorithms are based on a feedback loop which considers the direction and distance to the target at each step and then applying a chosen acoustic force. The methods rely on using two resonant frequencies: the first one is the acoustic half-wave resonance frequency that functions to levitate the particles at the half-height of the device using the axial radiation force; the second resonance frequency is chosen from a set of possible resonances, and functions to shift levitated particles in the required direction.

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Published date: January 2019

Identifiers

Local EPrints ID: 456182
URI: http://eprints.soton.ac.uk/id/eprint/456182
PURE UUID: c9701f1b-f84a-46ae-9613-2c3027164e6d
ORCID for Peter Glynne-Jones: ORCID iD orcid.org/0000-0001-5684-3953

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Date deposited: 26 Apr 2022 15:25
Last modified: 17 Mar 2024 02:49

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Contributors

Author: Zaid Shaglwf
Thesis advisor: Peter Glynne-Jones ORCID iD

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