Functional capacity, sarcopenia, and bone health
Functional capacity, sarcopenia, and bone health
Bone and muscle are recognised as interacting tissues, the so-called ‘muscle-bone unit’, in which these two tissues communicate to coordinate their development (chemically and metabolically), as well as their response to loading or injury. Musculoskeletal disorders of ageing, specifically osteoporosis and sarcopenia, are highly prevalent in older individuals. They signify a significant burden for older people affecting their mobility, confidence, and quality of life, as well as being a major cost to healthcare systems worldwide. This review considers the coexistence of osteoporosis and sarcopenia in individuals and describes risk factors, clinical consequences, approaches to management, and the link with functional capacity.
Laskou, Faidra
3959d6e2-ccfa-4d97-8311-16f27b893365
Patel, Harnish
e1c0826f-d14e-49f3-8049-5b945d185523
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
1 September 2022
Laskou, Faidra
3959d6e2-ccfa-4d97-8311-16f27b893365
Patel, Harnish
e1c0826f-d14e-49f3-8049-5b945d185523
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
Laskou, Faidra, Patel, Harnish, Cooper, Cyrus and Dennison, Elaine
(2022)
Functional capacity, sarcopenia, and bone health.
Best Practice & Research Clinical Rheumatology, 36 (3), [101756].
(doi:10.1016/j.berh.2022.101756).
Abstract
Bone and muscle are recognised as interacting tissues, the so-called ‘muscle-bone unit’, in which these two tissues communicate to coordinate their development (chemically and metabolically), as well as their response to loading or injury. Musculoskeletal disorders of ageing, specifically osteoporosis and sarcopenia, are highly prevalent in older individuals. They signify a significant burden for older people affecting their mobility, confidence, and quality of life, as well as being a major cost to healthcare systems worldwide. This review considers the coexistence of osteoporosis and sarcopenia in individuals and describes risk factors, clinical consequences, approaches to management, and the link with functional capacity.
Text
Sarcopenia_functional_capacity_bone health_after revision
- Accepted Manuscript
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Accepted/In Press date: 3 May 2022
e-pub ahead of print date: 10 June 2022
Published date: 1 September 2022
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Local EPrints ID: 457309
URI: http://eprints.soton.ac.uk/id/eprint/457309
ISSN: 1521-6942
PURE UUID: b252e57b-d414-44a6-92a6-efe80c50026a
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Date deposited: 31 May 2022 16:56
Last modified: 18 Mar 2024 05:07
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Author:
Faidra Laskou
Author:
Harnish Patel
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