The University of Southampton
University of Southampton Institutional Repository

Three-site screening for sexually transmitted infections in men who have sex with men using online self-testing in an English sexual health service

Three-site screening for sexually transmitted infections in men who have sex with men using online self-testing in an English sexual health service
Three-site screening for sexually transmitted infections in men who have sex with men using online self-testing in an English sexual health service
Objectives: among men who have sex with men (MSM) in the United Kingdom (UK), chlamydia (CT) and gonorrhoea (NG) infections commonly occur asymptomatically at extragenital sites. Therefore, MSM seeking sexual health services are offered three-site (oropharyngeal, rectal, and urogenital) STI screening. To increase access to screening, some UK sexual health services enable asymptomatic service users to order free STI screening kits online for self-sampling at home. We sought to assess prevalence of overall and extragenital CT/NG infection amongst asymptomatic MSM who used online self-testing in Hampshire, UK.
Methods: we assessed prevalence of CT/NG infections from non-pooled samples amongst asymptomatic cisgender MSM using an administrative database with results from 5,601 STI screening kits returned between 20/12/2016-31/01/2020. We compared number of diagnoses of extragenital infection with urogenital results of the same individuals to determine prevalence of infection that would have been missed with urine testing alone.
Results: amongst 5051 valid CT and 5040 valid NG asymptomatic test results, overall prevalence was 5.9% (298/5051) and 4.5% (228/5040), respectively. Amongst MSM with asymptomatic CT, 71.8% (214/298) had extragenital infection only, 2 (1, N=298) =56.71, p<0.001. Amongst those with asymptomatic NG, 89.9% (205/228) had extragenital infection only, 2 (1, N=228) =145.281, p<0.001.
Conclusions: overall, most CT/NG infections amongst asymptomatic MSM who used online self-testing were extragenital. Given this and the likelihood of onward transmission from asymptomatic infection, it is recommended that three-site testing remain standard for MSM and free screening services be expanded in easily accessible ways.
Gonorrhoea, Online; MSM; Extragenital; Asymptomatic; Gay and Bisexual Men, STI, Screening, Online, MSM, Extragenital, Asymptomatic, Gay and bisexual men
1368-4973
Charin, Gideon
825eebb8-ed0d-46b1-a62a-6118da7b85d7
Symonds, Ynez
57a07944-cf5f-439a-9d60-ac6c80356378
Scholfield, Clare
be4d126a-3da1-444d-b562-c1fe05b6fdfd
Graham, Cynthia
ac400331-f231-4449-a69b-ec9a477224c8
Armstrong, Heather
3dc9c223-1a61-47ad-ab0b-50d06cddf4f2
Charin, Gideon
825eebb8-ed0d-46b1-a62a-6118da7b85d7
Symonds, Ynez
57a07944-cf5f-439a-9d60-ac6c80356378
Scholfield, Clare
be4d126a-3da1-444d-b562-c1fe05b6fdfd
Graham, Cynthia
ac400331-f231-4449-a69b-ec9a477224c8
Armstrong, Heather
3dc9c223-1a61-47ad-ab0b-50d06cddf4f2

Charin, Gideon, Symonds, Ynez, Scholfield, Clare, Graham, Cynthia and Armstrong, Heather (2022) Three-site screening for sexually transmitted infections in men who have sex with men using online self-testing in an English sexual health service. Sexually Transmitted Infections. (doi:10.1136/sextrans-2021-055243).

Record type: Article

Abstract

Objectives: among men who have sex with men (MSM) in the United Kingdom (UK), chlamydia (CT) and gonorrhoea (NG) infections commonly occur asymptomatically at extragenital sites. Therefore, MSM seeking sexual health services are offered three-site (oropharyngeal, rectal, and urogenital) STI screening. To increase access to screening, some UK sexual health services enable asymptomatic service users to order free STI screening kits online for self-sampling at home. We sought to assess prevalence of overall and extragenital CT/NG infection amongst asymptomatic MSM who used online self-testing in Hampshire, UK.
Methods: we assessed prevalence of CT/NG infections from non-pooled samples amongst asymptomatic cisgender MSM using an administrative database with results from 5,601 STI screening kits returned between 20/12/2016-31/01/2020. We compared number of diagnoses of extragenital infection with urogenital results of the same individuals to determine prevalence of infection that would have been missed with urine testing alone.
Results: amongst 5051 valid CT and 5040 valid NG asymptomatic test results, overall prevalence was 5.9% (298/5051) and 4.5% (228/5040), respectively. Amongst MSM with asymptomatic CT, 71.8% (214/298) had extragenital infection only, 2 (1, N=298) =56.71, p<0.001. Amongst those with asymptomatic NG, 89.9% (205/228) had extragenital infection only, 2 (1, N=228) =145.281, p<0.001.
Conclusions: overall, most CT/NG infections amongst asymptomatic MSM who used online self-testing were extragenital. Given this and the likelihood of onward transmission from asymptomatic infection, it is recommended that three-site testing remain standard for MSM and free screening services be expanded in easily accessible ways.

Text
MSM three site screening manuscript (Mar 22, 2022) Accepted version - Accepted Manuscript
Restricted to Repository staff only until 2 June 2023.
Request a copy

More information

Accepted/In Press date: 14 May 2022
e-pub ahead of print date: 2 June 2022
Keywords: Gonorrhoea, Online; MSM; Extragenital; Asymptomatic; Gay and Bisexual Men, STI, Screening, Online, MSM, Extragenital, Asymptomatic, Gay and bisexual men

Identifiers

Local EPrints ID: 457469
URI: http://eprints.soton.ac.uk/id/eprint/457469
ISSN: 1368-4973
PURE UUID: d19522b7-3c87-42cc-944c-84136b3fc28c
ORCID for Cynthia Graham: ORCID iD orcid.org/0000-0002-7884-599X
ORCID for Heather Armstrong: ORCID iD orcid.org/0000-0002-1071-8644

Catalogue record

Date deposited: 09 Jun 2022 16:51
Last modified: 30 Jun 2022 02:00

Export record

Altmetrics

Contributors

Author: Gideon Charin
Author: Ynez Symonds
Author: Clare Scholfield
Author: Cynthia Graham ORCID iD

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×