Atheroma or ischemia: which is more important for managing patients with stable chest pain?

Hinton, Jonathan, Bashar, Hussein and Curzen, Nick (2022) Atheroma or ischemia: which is more important for managing patients with stable chest pain? Future Cardiology, 18 (5), 417-429. (doi:10.2217/fca-2021-0053).

Record type: Review

Abstract

In the evaluation and management of patients with stable chest pain/chronic coronary syndrome, cardiologists need to be able to weigh up the relative merits of managing these patients using either optimal therapy alone or optimal therapy plus revascularization. These decisions rely on an understanding of both the presence and the degree of coronary atheroma and myocardial ischemia, and the impact that these have on patients' symptoms and their prognosis. In this review the authors examine the relative impact of the anatomical and physiological assessment of patients with chronic coronary syndrome and how it can be used to achieve optimal and tailored therapy.

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Atheroma or ischaemia - Rev1.3 - Clear - Accepted Manuscript

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Accepted/In Press date: 2 December 2021

e-pub ahead of print date: 1 April 2022

Published date: 1 May 2022

Additional Information: Funding Information: J Hinton received speaker fees from Pfizer and travel sponsorship from Bayer. N Curzen received unrestricted research grants from HeartFlow, Boston Scientific and Beckmann Coulter; speaker fees/consultancy from HeartFlow, Boston Scientific, Abbott; travel sponsorship from Edwards, Biosensors, Medtronic, Boston Scientific. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. Funding Information: J Hinton received speaker fees from Pfizer and travel sponsorship from Bayer. N Curzen received unrestricted research grants from HeartFlow, Boston Scientific and Beckmann Coulter; speaker fees/consultancy from HeartFlow, Boston Scientific, Abbott; travel sponsorship from Edwards, Biosensors, Medtronic, Boston Scientific. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript. Publisher Copyright: © 2022 Future Medicine Ltd.

Keywords: CABG, PCI, atheroma, chest pain, ischemia, medical treatment, prognosis

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