An investigation into the electrochemical properties of nanostructured metals and their application as amperometric biosensors
An investigation into the electrochemical properties of nanostructured metals and their application as amperometric biosensors
In this work nanostructured materials have been electrodeposited onto conducting substrates using lyotropic liquid crystal phases and assemblies of colloidal particles as templates. These two methodologies offer access to structures with pore sizes in both the mesoporous and macroporous (2 – 50nm, and > 50 nm respectively, by IUPAC definition) ranges. The unique properties of these materials have been investigated with a view to producing improved amperometric biosensors.
The electrochemistry of hydrogen peroxide, ascorbate and glucose has been investigated using both unstructured and mesoporous platinum, palladium and rhodium microdisc electrodes. It would appear that the Hall mechanism (Hall et al. Electrochim. Acta, 43 (5-6), 579, 1998) of hydrogen peroxide oxidation operates at all three metals, but with improved efficiency at the nanostructures. When modified with a glucose oxidase/polymer matrix, the mesoporous electrodes were able to detect glucose at lower overpotentials and showed greater stability than their unstructured counterparts. Mesoporous platinum and palladium may be used for the direct oxidation of aqueous glucose.
The structure and pore connectivity of macroporous gold deposits is investigated by cyclic voltammetry in sulphuric acid. Values for the area of contact between template spheres and the substrate agree well with those in the literature as measured by scanning electron microscopy. Preliminary results on the ordered immobilisation of histadine tagged green fluorescent protein molecules within macrostructures are reported.
Recessed microdisc electrodes were used as substrates for the electrodeposition of mesoporous platinum and macroporous gold. This allowed deposition of thick (up to ~ 10μm) mesoporous platinum films at increased Faradaic efficiency (~ 66% compared to ~ 43% for deposition at similar inlaid microdiscs) without alteration of the electrode geometry.
University of Southampton
Cook, David Andrew
9e2710a1-3fc3-4a02-b8df-79ddfa886f6e
2005
Cook, David Andrew
9e2710a1-3fc3-4a02-b8df-79ddfa886f6e
Cook, David Andrew
(2005)
An investigation into the electrochemical properties of nanostructured metals and their application as amperometric biosensors.
University of Southampton, Doctoral Thesis.
Record type:
Thesis
(Doctoral)
Abstract
In this work nanostructured materials have been electrodeposited onto conducting substrates using lyotropic liquid crystal phases and assemblies of colloidal particles as templates. These two methodologies offer access to structures with pore sizes in both the mesoporous and macroporous (2 – 50nm, and > 50 nm respectively, by IUPAC definition) ranges. The unique properties of these materials have been investigated with a view to producing improved amperometric biosensors.
The electrochemistry of hydrogen peroxide, ascorbate and glucose has been investigated using both unstructured and mesoporous platinum, palladium and rhodium microdisc electrodes. It would appear that the Hall mechanism (Hall et al. Electrochim. Acta, 43 (5-6), 579, 1998) of hydrogen peroxide oxidation operates at all three metals, but with improved efficiency at the nanostructures. When modified with a glucose oxidase/polymer matrix, the mesoporous electrodes were able to detect glucose at lower overpotentials and showed greater stability than their unstructured counterparts. Mesoporous platinum and palladium may be used for the direct oxidation of aqueous glucose.
The structure and pore connectivity of macroporous gold deposits is investigated by cyclic voltammetry in sulphuric acid. Values for the area of contact between template spheres and the substrate agree well with those in the literature as measured by scanning electron microscopy. Preliminary results on the ordered immobilisation of histadine tagged green fluorescent protein molecules within macrostructures are reported.
Recessed microdisc electrodes were used as substrates for the electrodeposition of mesoporous platinum and macroporous gold. This allowed deposition of thick (up to ~ 10μm) mesoporous platinum films at increased Faradaic efficiency (~ 66% compared to ~ 43% for deposition at similar inlaid microdiscs) without alteration of the electrode geometry.
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Published date: 2005
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Local EPrints ID: 465709
URI: http://eprints.soton.ac.uk/id/eprint/465709
PURE UUID: 512f3326-017a-4e31-83e9-4db2c5d1909a
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Date deposited: 05 Jul 2022 02:41
Last modified: 16 Mar 2024 20:20
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David Andrew Cook
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