A study of sacral tissue tolerance to pressure using transcutaneous measurements of oxygen and carbon dioxide
A study of sacral tissue tolerance to pressure using transcutaneous measurements of oxygen and carbon dioxide
Transcutaneous partial pressure monitoring of oxygen (tcPO2) is widely used to assess tissue perfusion, and interest in the value of transcutaneous partial pressure monitoring of carbon dioxide (tcPCO2) has been growing. The objective of this work was to examine the relationship between individuals’ peak sacral interface pressure, changes in tcPO2 and tcPCO2 levels and capillary blood flow to assess individuals’ tolerance to pressure exerted through their own body mass.
Measurements were undertaken on healthy volunteers and identified four patterns of response of tcPO2 and three of tcPCO2 reflecting the varying degrees to which tissue perfusion was compromised and the ability of the tissue to tolerate and respond to pressure. In order to compare the response of individuals’ sacral tissue to pressure the maximum level of tcPO2 and tcPCO2 achieved when subjected to pressure and the total area under the curve (AUC) were used to reflect the loss of oxygen and accumulation of carbon dioxide. As well as inter-subject variation, intra-subject variation was observed with a significant difference identified between the responses of tcPO2 and tcPCO2 for individual’s left and right sacral sites. This supports the need for sites to be treated as independent sites.
No association was found between body mass index (BMI) and peak sacral pressure, or between BMI, peak sacral pressure and response type of tcPO2 and tcPCO2.
The study indicates that tcPCO2 is a more significant indicator of sacral tissues’ tolerance to pressure than tcPO2, and that the response type (Type A(iii)) of tcPCO2 is representative of total capillary closure with a significant accumulation of carbon dioxide (12-22.4kPa). This may play a role in identifying individual’s level of tolerance to pressure and susceptibility to tissue damage, which would prove invaluable to patients and the National Health Services alike. Further work is required to understand the point of tissue death.
University of Southampton
Sillitoe, Judith Ann
9f10e031-aea5-4461-8cec-fd0cf5c3b161
2007
Sillitoe, Judith Ann
9f10e031-aea5-4461-8cec-fd0cf5c3b161
Sillitoe, Judith Ann
(2007)
A study of sacral tissue tolerance to pressure using transcutaneous measurements of oxygen and carbon dioxide.
University of Southampton, Doctoral Thesis.
Record type:
Thesis
(Doctoral)
Abstract
Transcutaneous partial pressure monitoring of oxygen (tcPO2) is widely used to assess tissue perfusion, and interest in the value of transcutaneous partial pressure monitoring of carbon dioxide (tcPCO2) has been growing. The objective of this work was to examine the relationship between individuals’ peak sacral interface pressure, changes in tcPO2 and tcPCO2 levels and capillary blood flow to assess individuals’ tolerance to pressure exerted through their own body mass.
Measurements were undertaken on healthy volunteers and identified four patterns of response of tcPO2 and three of tcPCO2 reflecting the varying degrees to which tissue perfusion was compromised and the ability of the tissue to tolerate and respond to pressure. In order to compare the response of individuals’ sacral tissue to pressure the maximum level of tcPO2 and tcPCO2 achieved when subjected to pressure and the total area under the curve (AUC) were used to reflect the loss of oxygen and accumulation of carbon dioxide. As well as inter-subject variation, intra-subject variation was observed with a significant difference identified between the responses of tcPO2 and tcPCO2 for individual’s left and right sacral sites. This supports the need for sites to be treated as independent sites.
No association was found between body mass index (BMI) and peak sacral pressure, or between BMI, peak sacral pressure and response type of tcPO2 and tcPCO2.
The study indicates that tcPCO2 is a more significant indicator of sacral tissues’ tolerance to pressure than tcPO2, and that the response type (Type A(iii)) of tcPCO2 is representative of total capillary closure with a significant accumulation of carbon dioxide (12-22.4kPa). This may play a role in identifying individual’s level of tolerance to pressure and susceptibility to tissue damage, which would prove invaluable to patients and the National Health Services alike. Further work is required to understand the point of tissue death.
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Published date: 2007
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Local EPrints ID: 466708
URI: http://eprints.soton.ac.uk/id/eprint/466708
PURE UUID: aeea44ca-60a8-4630-a6e7-346cc0d7d17f
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Date deposited: 05 Jul 2022 06:25
Last modified: 16 Mar 2024 20:50
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Author:
Judith Ann Sillitoe
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