Systematic review of health-related quality of life (HRQoL) issues associated with gastric cancer: capturing cross-cultural differences
Systematic review of health-related quality of life (HRQoL) issues associated with gastric cancer: capturing cross-cultural differences
The treatment landscape for gastric cancer (GC) is constantly evolving with therapies affecting all aspects of health-related quality of life (HRQoL) which need careful monitoring. While there are HRQoL measures designed specifically to capture issues relevant to patients with GC, these might be outdated and only relevant to patients in westernised cultures. This review identifies the patient-reported measures used to assess HRQoL of patients with GC and compares the HRQoL measures used across cultures including East Asia, where GC is more prevalent. We conducted a systematic review of publications between January 2001 and January 2021. A total of 267 papers were identified; the majority (66%) of studies involved patients from East Asian countries. Out of the 24 HRQoL questionnaires captured, the European Organisation for Research and Treatment of Cancer Core Cancer measure (QLQ-C30) was the most widely used (60% of all studies and 62% of those involving patients from East Asian countries), followed by its gastric cancer-specific module (QLQ-STO22, 34% of all studies and 41% from East Asia). Eight questionnaires were developed within East Asian countries and, of the 20 studies including bespoke questions, 16 were from East Asia. There were six qualitative studies. HRQoL issues captured include diarrhoea, constipation, reflux, abdominal pain and abdominal fulness or bloating, difficulty swallowing, restricted eating, and weight loss. Psychosocial issues related to these problems were also assessed. Issues relating to the compatibility of some of the westernised measures within East Asian cultures were highlighted.
Cross-cultural comparison, Gastric cancer, Health-related quality of life, Patient-reported outcome measures
665-677
Rowsell, Alison
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Sodergren, Samantha C.
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Vassiliou, Vassilios
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Darlington, Anne-sophie
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Guren, Marianne G.
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Alkhaffaf, Bilal
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Moorbey, Chantelle
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Dennis, Kristopher
30b6e211-17c5-453d-9dd7-e4374fe92d14
Terada, Mistumi
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11 June 2022
Rowsell, Alison
ec8c6957-7e42-4c4e-b2d0-fbdf0c450a49
Sodergren, Samantha C.
d66fc3fa-2c98-403d-8ae5-410ef95de46e
Vassiliou, Vassilios
2f17223f-b322-4752-9f1b-f4bc7e4af047
Darlington, Anne-sophie
472fcfc9-160b-4344-8113-8dd8760ff962
Guren, Marianne G.
467790c8-dd85-4f02-b971-cd57ba60c5f5
Alkhaffaf, Bilal
2065b48d-d01a-4b62-b98b-e5351cb41664
Moorbey, Chantelle
9096fc35-4105-43f1-9944-a1d192f72681
Dennis, Kristopher
30b6e211-17c5-453d-9dd7-e4374fe92d14
Terada, Mistumi
23c8d6e4-2f37-47c9-b787-e7410b48fd83
Rowsell, Alison, Sodergren, Samantha C., Vassiliou, Vassilios, Darlington, Anne-sophie, Guren, Marianne G., Alkhaffaf, Bilal, Moorbey, Chantelle, Dennis, Kristopher and Terada, Mistumi
(2022)
Systematic review of health-related quality of life (HRQoL) issues associated with gastric cancer: capturing cross-cultural differences.
Gastric Cancer, 25 (4), .
(doi:10.1007/s10120-022-01309-6).
Abstract
The treatment landscape for gastric cancer (GC) is constantly evolving with therapies affecting all aspects of health-related quality of life (HRQoL) which need careful monitoring. While there are HRQoL measures designed specifically to capture issues relevant to patients with GC, these might be outdated and only relevant to patients in westernised cultures. This review identifies the patient-reported measures used to assess HRQoL of patients with GC and compares the HRQoL measures used across cultures including East Asia, where GC is more prevalent. We conducted a systematic review of publications between January 2001 and January 2021. A total of 267 papers were identified; the majority (66%) of studies involved patients from East Asian countries. Out of the 24 HRQoL questionnaires captured, the European Organisation for Research and Treatment of Cancer Core Cancer measure (QLQ-C30) was the most widely used (60% of all studies and 62% of those involving patients from East Asian countries), followed by its gastric cancer-specific module (QLQ-STO22, 34% of all studies and 41% from East Asia). Eight questionnaires were developed within East Asian countries and, of the 20 studies including bespoke questions, 16 were from East Asia. There were six qualitative studies. HRQoL issues captured include diarrhoea, constipation, reflux, abdominal pain and abdominal fulness or bloating, difficulty swallowing, restricted eating, and weight loss. Psychosocial issues related to these problems were also assessed. Issues relating to the compatibility of some of the westernised measures within East Asian cultures were highlighted.
Text
Systematic Review of Health-Related Quality of Life
More information
Accepted/In Press date: 17 May 2022
Published date: 11 June 2022
Additional Information:
Funding Information:
This work supported by funding received from the European Organisation for Research And Treatment of Cancer Quality of Life Group awarded to SS, MT and VV (Grant reference 003–2019). MG received funding from the Norwegian Cancer Society (grant number 190188–2017). CM’s PhD. is funded by the Novo Nordisk UK Research Foundation. All other authors have no conflict of interest to declare.
Publisher Copyright:
© 2022, The Author(s).
Keywords:
Cross-cultural comparison, Gastric cancer, Health-related quality of life, Patient-reported outcome measures
Identifiers
Local EPrints ID: 467751
URI: http://eprints.soton.ac.uk/id/eprint/467751
ISSN: 1436-3291
PURE UUID: f0b55c30-0f41-4241-a47a-7a40bb0f4144
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Date deposited: 21 Jul 2022 17:01
Last modified: 17 Mar 2024 03:31
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Contributors
Author:
Alison Rowsell
Author:
Vassilios Vassiliou
Author:
Marianne G. Guren
Author:
Bilal Alkhaffaf
Author:
Chantelle Moorbey
Author:
Kristopher Dennis
Author:
Mistumi Terada
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