The University of Southampton
×
Filter your search:
University of Southampton Institutional Repository

Dataset to support the Southampton Doctoral Thesis 'The Influence of Germline Genotype on Breast Cancer Tumour Phenotype'

Dataset to support the Southampton Doctoral Thesis 'The Influence of Germline Genotype on Breast Cancer Tumour Phenotype'
Dataset to support the Southampton Doctoral Thesis 'The Influence of Germline Genotype on Breast Cancer Tumour Phenotype'
Summary level data derived from The 100,000 Genomes Project, Rare Disease, Familial Breast Cancer and Cancer, Breast Cancer Recruitment Domains. Data exported via the Genomics England secure AirLock system. This includes the number of pathogenic/likely pathogenic variant identified in BRCA, PALB2, CHEK2, ATM and TP53. It compares the age of cancer onset between gene carriers and non-carriers. It also compares the Tumour Mutational Burden, Somatic Mutational Signature and Somatic Mutational Profile between gene carriers and non-carriers.
University of Southampton
Greville-Heygate, Stephanie Leanne
a952c82d-8775-45a5-9c60-478348fb02f2
Tapper, William
9d5ddc92-a8dd-4c78-ac67-c5867b62724c
Greville-Heygate, Stephanie Leanne
a952c82d-8775-45a5-9c60-478348fb02f2
Tapper, William
9d5ddc92-a8dd-4c78-ac67-c5867b62724c

Greville-Heygate, Stephanie Leanne (2022) Dataset to support the Southampton Doctoral Thesis 'The Influence of Germline Genotype on Breast Cancer Tumour Phenotype'. University of Southampton doi:10.5258/SOTON/D1618 [Dataset]

Record type: Dataset

Abstract

Summary level data derived from The 100,000 Genomes Project, Rare Disease, Familial Breast Cancer and Cancer, Breast Cancer Recruitment Domains. Data exported via the Genomics England secure AirLock system. This includes the number of pathogenic/likely pathogenic variant identified in BRCA, PALB2, CHEK2, ATM and TP53. It compares the age of cancer onset between gene carriers and non-carriers. It also compares the Tumour Mutational Burden, Somatic Mutational Signature and Somatic Mutational Profile between gene carriers and non-carriers.

Archive
Data_for_Deposit.zip - Dataset
Available under License Creative Commons Attribution.
Download (41kB)
Text
thesis_readme._Heygate.txt - Dataset
Download (1kB)

More information

Published date: August 2022

Identifiers

Local EPrints ID: 468375
URI: http://eprints.soton.ac.uk/id/eprint/468375
DOI: doi:10.5258/SOTON/D1618
PURE UUID: a90c05b3-8d53-47c7-a6ad-a19b23d71d76
ORCID for William Tapper: ORCID iD orcid.org/0000-0002-5896-1889

Catalogue record

Date deposited: 11 Aug 2022 16:57
Last modified: 06 May 2023 01:36

Export record

Altmetrics

Contributors

Creator: Stephanie Leanne Greville-Heygate
Research team head: William Tapper ORCID iD

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Library staff additional information
Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×