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Dataset to support the Southampton Doctoral thesis "Characterisation of novel human CD27-specific antibodies for cancer therapy"

Dataset to support the Southampton Doctoral thesis "Characterisation of novel human CD27-specific antibodies for cancer therapy"
Dataset to support the Southampton Doctoral thesis "Characterisation of novel human CD27-specific antibodies for cancer therapy"
The dataset supports a thesis "Characterisation of novel human CD27-specific antibodies for cancer therapy". The dataset includes four excel spreadsheets containing raw data for each result chapter of the thesis, subdivided by figure numbers. Parts of this data have been published in: Heckel, F., Turaj, A.H., Fisher, H. et al. Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering. Commun Biol 5, 229 (2022). https://doi.org/10.1038/s42003-022-03182-6
University of Southampton
Heckel, Franziska
9b776ae0-b3a5-487c-9bbc-36d4038c2157
Lim, Sean
1afe5aa1-61a4-4a7b-927f-5e671f885196
Beers, Stephen
a02548be-3ffd-41ab-9db8-d6e8c3b499a2
Heckel, Franziska
9b776ae0-b3a5-487c-9bbc-36d4038c2157
Lim, Sean
1afe5aa1-61a4-4a7b-927f-5e671f885196
Beers, Stephen
a02548be-3ffd-41ab-9db8-d6e8c3b499a2

Heckel, Franziska (2022) Dataset to support the Southampton Doctoral thesis "Characterisation of novel human CD27-specific antibodies for cancer therapy". University of Southampton doi:10.5258/SOTON/D2337 [Dataset]

Record type: Dataset

Abstract

The dataset supports a thesis "Characterisation of novel human CD27-specific antibodies for cancer therapy". The dataset includes four excel spreadsheets containing raw data for each result chapter of the thesis, subdivided by figure numbers. Parts of this data have been published in: Heckel, F., Turaj, A.H., Fisher, H. et al. Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering. Commun Biol 5, 229 (2022). https://doi.org/10.1038/s42003-022-03182-6

Text
Franziska_Heckel_Readme_File_to_support_the_Dataset.txt - Dataset
Available under License Creative Commons Attribution.
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Spreadsheet
Data_Chapter_4_Functional_investigation_of_hCD27_mAbs.xlsx - Dataset
Available under License Creative Commons Attribution.
Download (863kB)
Spreadsheet
Data_Chapter_3_Characterisation_of_anti_hCD27_mAb_binding.xlsx - Dataset
Available under License Creative Commons Attribution.
Download (1MB)
Spreadsheet
Data_Chapter_5_Anti_CD27_anti_CD38_mAb_combination_therapy_in_vivo.xlsx - Dataset
Available under License Creative Commons Attribution.
Download (758kB)
Spreadsheet
Data_Chapter_6_In_vitro_myeloid_stimulation_by_anti_hCD27_mAbs.xlsx - Dataset
Available under License Creative Commons Attribution.
Download (923kB)

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More information

Published date: 29 August 2022
Related URLs:

Identifiers

Local EPrints ID: 468850
URI: http://eprints.soton.ac.uk/id/eprint/468850
DOI: doi:10.5258/SOTON/D2337
PURE UUID: b3f09ef8-cad0-4544-9a51-03b25a3f24df
ORCID for Franziska Heckel: ORCID iD orcid.org/0000-0002-7564-1932
ORCID for Stephen Beers: ORCID iD orcid.org/0000-0002-3765-3342

Catalogue record

Date deposited: 30 Aug 2022 16:39
Last modified: 06 May 2023 01:38

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Contributors

Creator: Franziska Heckel ORCID iD
Research team head: Sean Lim
Research team head: Stephen Beers ORCID iD

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