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How is oral isotretinoin prescribed for the treatment of acne vulgaris? Results from a UK Dermatology Clinical Trials Network (UKDCTN) and British Dermatological Nursing Group (BDNG) survey of health professionals

How is oral isotretinoin prescribed for the treatment of acne vulgaris? Results from a UK Dermatology Clinical Trials Network (UKDCTN) and British Dermatological Nursing Group (BDNG) survey of health professionals
How is oral isotretinoin prescribed for the treatment of acne vulgaris? Results from a UK Dermatology Clinical Trials Network (UKDCTN) and British Dermatological Nursing Group (BDNG) survey of health professionals
We undertook a survey of UK healthcare professionals through the UKDCTN and BDNG to understand clinicians’ routine practice prescribing oral isotretinoin for treatment of acne vulgaris (acne). We also wanted to understand clinicians’ experiences and views on prescribing low daily dose regimens. Overall, the survey showed that clinicians adopted a patient-centred approach when deciding isotretinoin dosing. The rationale for using a low-dose regimen varied, but was focused on patient wellbeing during treatment. Some clinicians were concerned that use of a low-dose regimen could be less effective and lead to longer treatment durations. The survey results will be useful to inform a clinical trial investigating the effectiveness and safety of low daily dose isotretinoin for the treatment of acne.
0307-6938
Moledina, Zahra
fde6d28d-5ed5-4351-a7a5-aa00b1470657
McPhee, Margaret
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Ravenscroft, Jane
c04b5faa-bcd0-4d5d-a5ff-44b3342e4ced
Healy, Eugene
Radley, Kathy
870ce00b-0f91-48cd-a787-22e6476ccdf5
Thomas, Kim S
a1fb9576-e4e3-4829-ac19-3dd1b3938557
Burden-Teh, Esther
4b1ee272-e52e-40dc-b517-cdaa9dac233b
Moledina, Zahra
fde6d28d-5ed5-4351-a7a5-aa00b1470657
McPhee, Margaret
77faabbb-7dc6-4c5f-8bd6-26401eadb8f5
Ravenscroft, Jane
c04b5faa-bcd0-4d5d-a5ff-44b3342e4ced
Healy, Eugene
Radley, Kathy
870ce00b-0f91-48cd-a787-22e6476ccdf5
Thomas, Kim S
a1fb9576-e4e3-4829-ac19-3dd1b3938557
Burden-Teh, Esther
4b1ee272-e52e-40dc-b517-cdaa9dac233b

Moledina, Zahra, McPhee, Margaret, Ravenscroft, Jane, Healy, Eugene, Radley, Kathy, Thomas, Kim S and Burden-Teh, Esther (2022) How is oral isotretinoin prescribed for the treatment of acne vulgaris? Results from a UK Dermatology Clinical Trials Network (UKDCTN) and British Dermatological Nursing Group (BDNG) survey of health professionals. Clinical and Experimental Dermatology. (doi:10.1093/ced/llac015).

Record type: Article

Abstract

We undertook a survey of UK healthcare professionals through the UKDCTN and BDNG to understand clinicians’ routine practice prescribing oral isotretinoin for treatment of acne vulgaris (acne). We also wanted to understand clinicians’ experiences and views on prescribing low daily dose regimens. Overall, the survey showed that clinicians adopted a patient-centred approach when deciding isotretinoin dosing. The rationale for using a low-dose regimen varied, but was focused on patient wellbeing during treatment. Some clinicians were concerned that use of a low-dose regimen could be less effective and lead to longer treatment durations. The survey results will be useful to inform a clinical trial investigating the effectiveness and safety of low daily dose isotretinoin for the treatment of acne.

Text
How is isotretinoin prescribed for the treatment of acne vulgaris - Revised MANUSCRIPT_clean copy - Accepted Manuscript
Restricted to Repository staff only until 20 October 2023.

More information

Accepted/In Press date: 15 September 2022
Published date: 20 October 2022
Additional Information: Dermatology output

Identifiers

Local EPrints ID: 471567
URI: http://eprints.soton.ac.uk/id/eprint/471567
ISSN: 0307-6938
PURE UUID: 0821da0e-d4f9-43f8-982c-4ab425c790a2

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Date deposited: 11 Nov 2022 17:41
Last modified: 11 Nov 2022 17:41

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Contributors

Author: Zahra Moledina
Author: Margaret McPhee
Author: Jane Ravenscroft
Author: Eugene Healy
Author: Kathy Radley
Author: Kim S Thomas
Author: Esther Burden-Teh

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