Transatlantic progress in measurement of cognitive outcomes in paediatric oncology trials
Transatlantic progress in measurement of cognitive outcomes in paediatric oncology trials
The importance of measuring quality of survival within paediatric oncology trials is increasingly recognised. However, capturing neuropsychological outcomes and other aspects of quality of survival in the context of large or multinational trials can be challenging. We provide examples of protocols designed to address this challenge recently employed in clinical trials in the USA and Europe. We discuss their respective strengths and challenges, obstacles encountered and future opportunities for transatlantic collaboration.
brain tumour, cancer, child, cognitive, late effects, paediatric, quality of survival
Thomas, Sophie
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Embry, Leanne
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Walsh, Karin
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Bull, Kim
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Grundy, Richard
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Kennedy, Colin
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Lemiere, Jurgen
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Hernáiz Driever, Pablo
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Limond, Jennifer
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Chevignard, Mathilde
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Hardy, Kristina
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May 2023
Thomas, Sophie
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Embry, Leanne
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Walsh, Karin
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Bull, Kim
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Grundy, Richard
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Kennedy, Colin
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Lemiere, Jurgen
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Hernáiz Driever, Pablo
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Limond, Jennifer
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Chevignard, Mathilde
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Hardy, Kristina
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Thomas, Sophie, Embry, Leanne, Walsh, Karin, Bull, Kim, Grundy, Richard, Kennedy, Colin, Lemiere, Jurgen, Hernáiz Driever, Pablo, Limond, Jennifer, Chevignard, Mathilde and Hardy, Kristina
(2023)
Transatlantic progress in measurement of cognitive outcomes in paediatric oncology trials.
Pediatric Blood and Cancer, 70 (5), [e30171].
(doi:10.1002/pbc.30171).
Abstract
The importance of measuring quality of survival within paediatric oncology trials is increasingly recognised. However, capturing neuropsychological outcomes and other aspects of quality of survival in the context of large or multinational trials can be challenging. We provide examples of protocols designed to address this challenge recently employed in clinical trials in the USA and Europe. We discuss their respective strengths and challenges, obstacles encountered and future opportunities for transatlantic collaboration.
Text
Transatlantic Progress In Measurement of Cognitive Outcomes accepted manuscript Nov 24 2022
- Accepted Manuscript
Text
Pediatric Blood Cancer - 2023 - Thomas - Transatlantic progress in measurement of cognitive outcomes in paediatric
- Version of Record
More information
Accepted/In Press date: 24 November 2022
e-pub ahead of print date: 3 February 2023
Published date: May 2023
Additional Information:
Publisher Copyright:
© 2023 The Authors. Pediatric Blood & Cancer published by Wiley Periodicals LLC.
Keywords:
brain tumour, cancer, child, cognitive, late effects, paediatric, quality of survival
Identifiers
Local EPrints ID: 473707
URI: http://eprints.soton.ac.uk/id/eprint/473707
ISSN: 1545-5017
PURE UUID: 9a8d04fe-9c55-4a4a-800a-fa2ba593f48f
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Date deposited: 27 Jan 2023 17:54
Last modified: 17 Mar 2024 02:48
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Contributors
Author:
Sophie Thomas
Author:
Leanne Embry
Author:
Karin Walsh
Author:
Richard Grundy
Author:
Jurgen Lemiere
Author:
Pablo Hernáiz Driever
Author:
Jennifer Limond
Author:
Mathilde Chevignard
Author:
Kristina Hardy
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