The need to distinguish intervention thresholds and diagnostic thresholds in the management of osteoporosis

Accepted/In Press date: 30 September 2022

e-pub ahead of print date: 25 October 2022

Published date: January 2023

Additional Information: Funding Information: The conceptual description of osteoporosis dates back nearly 30 years arising from an international consensus conference held in Hong Kong in March 1993, sponsored by the National Institute of Arthritis and Musculoskeletal and Skin Diseases, the European Foundation for Osteoporosis and Bone Disease (now the International Osteoporosis Foundation) and the American National Osteoporosis Foundation (now the Bone Health and Osteoporosis Foundation) []. Osteoporosis was described as: ‘A systemic skeletal disease characterised by low bone mass and micro-architectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture’, a conceptual definition supported several years later by the NIH Consensus Development Panel on Osteoporosis []. Publisher Copyright: © 2022, International Osteoporosis Foundation and Bone Health and Osteoporosis Foundation.

Keywords: Definition, Diagnosis, FRAX, Fracture risk, Intervention thresholds, Osteoporosis

Local EPrints ID: 473808

URI: http://eprints.soton.ac.uk/id/eprint/473808

DOI: doi:10.1007/s00198-022-06567-9

ISSN: 0937-941X

PURE UUID: 90794bcb-35b2-4b2f-9ad6-ca285e03c3ae

ORCID for Nicholas C Harvey: orcid.org/0000-0002-8194-2512

ORCID for Cyrus Cooper: orcid.org/0000-0003-3510-0709

Date deposited: 01 Feb 2023 17:31

Last modified: 18 Mar 2024 05:03