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The need to distinguish intervention thresholds and diagnostic thresholds in the management of osteoporosis

The need to distinguish intervention thresholds and diagnostic thresholds in the management of osteoporosis
The need to distinguish intervention thresholds and diagnostic thresholds in the management of osteoporosis
This position paper of the International Osteoporosis Foundation (IOF) and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) addresses the rationale for separate diagnostic and intervention thresholds in osteoporosis. We conclude that the current BMD-based diagnostic criteria for osteoporosis be retained whilst clarity is brought to bear on the distinction between diagnostic and intervention thresholds.
Definition, Diagnosis, FRAX, Fracture risk, Intervention thresholds, Osteoporosis
0937-941X
1-9
Kanis, John A
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McCloskey, Eugene V.
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Harvey, Nicholas C
ce487fb4-d360-4aac-9d17-9466d6cba145
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Rizzoli, Rene
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Dawson-Hughes, Bess
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Maggi, Stefania
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Reginster, Jean-Yves
db56b103-184d-46e1-9600-f47f7a09a492
Kanis, John A
f1621d8d-8afb-4d97-9679-2165d88a344d
McCloskey, Eugene V.
2f057a16-3d4e-4597-80c7-6ce47f969c78
Harvey, Nicholas C
ce487fb4-d360-4aac-9d17-9466d6cba145
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Rizzoli, Rene
682e7962-68b1-469e-8049-754ad7892221
Dawson-Hughes, Bess
a9df73df-dff4-4a37-b358-abff8d5d2c2d
Maggi, Stefania
269c4058-6259-4392-a884-4fca4ffe5c68
Reginster, Jean-Yves
db56b103-184d-46e1-9600-f47f7a09a492

Kanis, John A, McCloskey, Eugene V., Harvey, Nicholas C, Cooper, Cyrus, Rizzoli, Rene, Dawson-Hughes, Bess, Maggi, Stefania and Reginster, Jean-Yves (2023) The need to distinguish intervention thresholds and diagnostic thresholds in the management of osteoporosis. Osteoporosis International, 34 (1), 1-9. (doi:10.1007/s00198-022-06567-9).

Record type: Article

Abstract

This position paper of the International Osteoporosis Foundation (IOF) and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) addresses the rationale for separate diagnostic and intervention thresholds in osteoporosis. We conclude that the current BMD-based diagnostic criteria for osteoporosis be retained whilst clarity is brought to bear on the distinction between diagnostic and intervention thresholds.

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Diagnosis of osteoporosis v7 OSIN-R109509 - Accepted Manuscript
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Accepted/In Press date: 30 September 2022
e-pub ahead of print date: 25 October 2022
Published date: January 2023
Additional Information: Funding Information: The conceptual description of osteoporosis dates back nearly 30 years arising from an international consensus conference held in Hong Kong in March 1993, sponsored by the National Institute of Arthritis and Musculoskeletal and Skin Diseases, the European Foundation for Osteoporosis and Bone Disease (now the International Osteoporosis Foundation) and the American National Osteoporosis Foundation (now the Bone Health and Osteoporosis Foundation) []. Osteoporosis was described as: ‘A systemic skeletal disease characterised by low bone mass and micro-architectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture’, a conceptual definition supported several years later by the NIH Consensus Development Panel on Osteoporosis []. Publisher Copyright: © 2022, International Osteoporosis Foundation and Bone Health and Osteoporosis Foundation.
Keywords: Definition, Diagnosis, FRAX, Fracture risk, Intervention thresholds, Osteoporosis

Identifiers

Local EPrints ID: 473808
URI: http://eprints.soton.ac.uk/id/eprint/473808
ISSN: 0937-941X
PURE UUID: 90794bcb-35b2-4b2f-9ad6-ca285e03c3ae
ORCID for Nicholas C Harvey: ORCID iD orcid.org/0000-0002-8194-2512
ORCID for Cyrus Cooper: ORCID iD orcid.org/0000-0003-3510-0709

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Date deposited: 01 Feb 2023 17:31
Last modified: 18 Mar 2024 05:03

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Contributors

Author: John A Kanis
Author: Eugene V. McCloskey
Author: Cyrus Cooper ORCID iD
Author: Rene Rizzoli
Author: Bess Dawson-Hughes
Author: Stefania Maggi
Author: Jean-Yves Reginster

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