Impaired expression of metallothioneins contributes to allergen-induced inflammation in patients with atopic dermatitis

Accepted/In Press date: 29 April 2023

e-pub ahead of print date: 19 May 2023

Published date: 19 May 2023

Additional Information: Funding Information: We acknowledge the use of the Iridis5 High-Performance Computing Facility and Flow Cytometry Core Facilities, together with support services at the University of Southampton. The authors wish to acknowledge Nikki Graham, Senior Technician within the DNA laboratory, Dr Carolann McGuire and Dr Richard Jewell from Flow Cytometry Core for technical support. We are grateful to the nurses and administrative staff at the Clinical Research Facility, NIHR, University Hospital Southampton NHS Foundation Trust. We express our deepest gratitude to the patients recruited to the study. This research was funded in whole by the Wellcome Trust [Sir Henry Dale Fellowship 109377/Z/15/Z, awarded to MEP]. The 10× Chromium Controller was funded by a Cancer Research UK Advanced Clinician Scientist Fellowship to Sean Hua Lim (A27179). For the purpose of open access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission. ML is funded by a BBSRC David Phillips Fellowship [BB/V004573/1], LSND was supported by an NIHR Southampton BRC Research Fellowship. Funding Information: We acknowledge the use of the Iridis5 High-Performance Computing Facility and Flow Cytometry Core Facilities, together with support services at the University of Southampton. The authors wish to acknowledge Nikki Graham, Senior Technician within the DNA laboratory, Dr Carolann McGuire and Dr Richard Jewell from Flow Cytometry Core for technical support. We are grateful to the nurses and administrative staff at the Clinical Research Facility, NIHR, University Hospital Southampton NHS Foundation Trust. We express our deepest gratitude to the patients recruited to the study. This research was funded in whole by the Wellcome Trust [Sir Henry Dale Fellowship 109377/Z/15/Z, awarded to MEP]. The 10× Chromium Controller was funded by a Cancer Research UK Advanced Clinician Scientist Fellowship to Sean Hua Lim (A27179). For the purpose of open access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission. ML is funded by a BBSRC David Phillips Fellowship [BB/V004573/1], LSND was supported by an NIHR Southampton BRC Research Fellowship. Publisher Copyright: © 2023, The Author(s).

Local EPrints ID: 477595

URI: http://eprints.soton.ac.uk/id/eprint/477595

DOI: doi:10.1038/s41467-023-38588-1

ISSN: 2041-1723

PURE UUID: bc779fc7-91dd-474f-9d86-d8dfd027fedd

ORCID for Sofia Sirvent: orcid.org/0000-0003-0050-8579

ORCID for Andres S. Vallejo: orcid.org/0000-0002-4688-0598

ORCID for Kalum Clayton: orcid.org/0000-0002-1143-3931

ORCID for Sarah Ennis: orcid.org/0000-0003-2648-0869

ORCID for Gemma Douilhet: orcid.org/0000-0003-0681-6986

ORCID for Lareb S.N. Dean: orcid.org/0000-0002-8703-9236

ORCID for Matthew Loxham: orcid.org/0000-0001-6459-538X

ORCID for Graham Roberts: orcid.org/0000-0003-2252-1248

ORCID for Michael R. Ardern-Jones: orcid.org/0000-0003-1466-2016

Date deposited: 09 Jun 2023 16:32

Last modified: 15 Aug 2024 02:13