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Effect of acceptance and commitment therapy for depressive disorders: a meta-analysis

Effect of acceptance and commitment therapy for depressive disorders: a meta-analysis
Effect of acceptance and commitment therapy for depressive disorders: a meta-analysis

Objective: to systematically evaluate the effect of Acceptance and Commitment Therapy (ACT) on depressive disorders.

Methods: the electronic databases of Web of Science Core Collection, Pubmed, EMBASE, Cochrane Library, PsycInfo, CNKI, Wanfang and Weipu were used to select relevant publications. Screening, data extraction, and quality assessment were undertaken following PRISMA guidelines for preferred reporting of systematic reviews and meta-analysis. RevMan5.4 was used for meta-analysis.

Results: 11 studies with a total of 962 patients were included. Random-effects model analysis showed that ACT could effectively reduce the level of depressive symptoms in patients with depressive disorders (SMD = - 1.05, 95% CI: - 1.43-- 0.66, P < 0.00001), improve psychological flexibility (MD = 4.84, 95% CI: 2.70-6.97, P < 0.00001), and have good maintenance effect (SMD = - 0.70, 95% CI: - 1.15-- 0.25, P = 0.002). All differences were statistically significant.

Conclusions: ACT not only improves depressive symptoms and psychological flexibility, but also has a good maintenance effect, and it is particularly effective in Chinese patients. Large randomized controlled trials are needed to validate the findings from this meta-analysis.

Acceptance and commitment therapy, Depressive disorders, Meta-analysis, Randomized controlled trial
1744-859X
34
Zhao, Bing
8b2300b0-8f10-4b19-b368-8287400c47dc
Wang, Qian
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Wang, Liping
ef5828b8-d874-42db-bb25-713890281af2
Chen, Jie
7181526d-ec25-480e-a35e-37bf4616e131
Yin, Tongtong
af90cfcf-b542-465f-97ba-5da0152f8f38
Zhang, Jingxuan
8985ba19-1f98-4261-8b8b-a45bc9e56197
Cheng, Xiaojing
9a93d740-2d0f-42af-8e05-0608f7bb3461
Hou, Ruihua
470bdcbc-93a9-4dad-aac5-26d455c34376
Zhao, Bing
8b2300b0-8f10-4b19-b368-8287400c47dc
Wang, Qian
8fdfc49b-7545-4455-b04d-43cf2ce251ad
Wang, Liping
ef5828b8-d874-42db-bb25-713890281af2
Chen, Jie
7181526d-ec25-480e-a35e-37bf4616e131
Yin, Tongtong
af90cfcf-b542-465f-97ba-5da0152f8f38
Zhang, Jingxuan
8985ba19-1f98-4261-8b8b-a45bc9e56197
Cheng, Xiaojing
9a93d740-2d0f-42af-8e05-0608f7bb3461
Hou, Ruihua
470bdcbc-93a9-4dad-aac5-26d455c34376

Zhao, Bing, Wang, Qian, Wang, Liping, Chen, Jie, Yin, Tongtong, Zhang, Jingxuan, Cheng, Xiaojing and Hou, Ruihua (2023) Effect of acceptance and commitment therapy for depressive disorders: a meta-analysis. Annals of General Psychiatry, 22 (1), 34, [34]. (doi:10.1186/s12991-023-00462-1).

Record type: Article

Abstract

Objective: to systematically evaluate the effect of Acceptance and Commitment Therapy (ACT) on depressive disorders.

Methods: the electronic databases of Web of Science Core Collection, Pubmed, EMBASE, Cochrane Library, PsycInfo, CNKI, Wanfang and Weipu were used to select relevant publications. Screening, data extraction, and quality assessment were undertaken following PRISMA guidelines for preferred reporting of systematic reviews and meta-analysis. RevMan5.4 was used for meta-analysis.

Results: 11 studies with a total of 962 patients were included. Random-effects model analysis showed that ACT could effectively reduce the level of depressive symptoms in patients with depressive disorders (SMD = - 1.05, 95% CI: - 1.43-- 0.66, P < 0.00001), improve psychological flexibility (MD = 4.84, 95% CI: 2.70-6.97, P < 0.00001), and have good maintenance effect (SMD = - 0.70, 95% CI: - 1.15-- 0.25, P = 0.002). All differences were statistically significant.

Conclusions: ACT not only improves depressive symptoms and psychological flexibility, but also has a good maintenance effect, and it is particularly effective in Chinese patients. Large randomized controlled trials are needed to validate the findings from this meta-analysis.

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e-pub ahead of print date: 7 September 2023
Published date: 7 September 2023
Additional Information: Funding Information: This review work received the funding support from National Natural Science Foundation of China International (Regional) Cooperation and Exchange Programme (China and Canada); Ref: 81761128033) and the Key Research and Development Programme of Shandong Province (Science and Technology scheme); Ref: 2021SFGC0504). Funding Information: We would like to thank the National Natural Science Foundation of China International (Regional) and the Key Research and Development Programme of Shandong Province (Science and Technology scheme) for the funding support. Publisher Copyright: © 2023, BioMed Central Ltd., part of Springer Nature.
Keywords: Acceptance and commitment therapy, Depressive disorders, Meta-analysis, Randomized controlled trial

Identifiers

Local EPrints ID: 481976
URI: http://eprints.soton.ac.uk/id/eprint/481976
ISSN: 1744-859X
PURE UUID: b833b4ba-2587-4bef-adc4-37f6aab366db
ORCID for Ruihua Hou: ORCID iD orcid.org/0000-0001-6127-1478

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Date deposited: 14 Sep 2023 16:45
Last modified: 18 Mar 2024 03:07

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Contributors

Author: Bing Zhao
Author: Qian Wang
Author: Liping Wang
Author: Jie Chen
Author: Tongtong Yin
Author: Jingxuan Zhang
Author: Xiaojing Cheng
Author: Ruihua Hou ORCID iD

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