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Cognitive behavioural therapy for psychosis: the end of the line or time for a new approach?

Cognitive behavioural therapy for psychosis: the end of the line or time for a new approach?
Cognitive behavioural therapy for psychosis: the end of the line or time for a new approach?

Purpose: following its introduction in the early 1990s, cognitive behavioural therapy for psychosis (CBTp) has been evaluated in a large number of clinical trials and is now established as a recommended treatment in the UK National Health Service and elsewhere in the world. Meta-analyses, however, indicate modest effects compared to treatment as usual or comparison therapies such as supportive counselling. Here, we seek to identify factors impacting the effectiveness of CBTp, and avenues for future psychotherapy research that may improve outcomes. 

Method: we outline two recent umbrella reviews and discuss factors likely to impact the effectiveness of CBTp. 

Results: modest effect sizes from meta-analyses mask heterogeneous outcomes, with some people benefiting and others possibly being harmed by therapy. Common factors such as the therapeutic alliance play an important role in determining outcomes but have been largely neglected by CBTp researchers. There is also the promise of improving outcomes by identifying and targeting the psychological mechanisms that either maintain psychotic symptoms (e.g. worry) or are causally implicated (e.g. trauma). 

Conclusions: it is unlikely that everyone with psychosis will be equally responsive to the same therapeutic protocols. We need a new, personalised psychotherapy approach to CBTp research and practice, and can learn from research for anxiety and depression examining predictors of therapeutic response to inform treatment decisions. Precision psychological therapies informed by a combination of individual characteristics, common factors and a focus on specific mechanisms will require new research strategies and are likely to lead to improved outcomes for people with psychosis.

CBT, CBTp, common factors, meta-analysis, outcomes, psychosis, therapeutic harm, umbrella review
1476-0835
Newman-Taylor, Katherine
e090b9da-6ede-45d5-8a56-2e86c2dafef7
Bentall, Richard
e2e952e2-336a-4545-b542-1806596df3a4
Newman-Taylor, Katherine
e090b9da-6ede-45d5-8a56-2e86c2dafef7
Bentall, Richard
e2e952e2-336a-4545-b542-1806596df3a4

Newman-Taylor, Katherine and Bentall, Richard (2023) Cognitive behavioural therapy for psychosis: the end of the line or time for a new approach? Psychology and Psychotherapy: Theory, Research and Practice. (doi:10.1111/papt.12498).

Record type: Article

Abstract

Purpose: following its introduction in the early 1990s, cognitive behavioural therapy for psychosis (CBTp) has been evaluated in a large number of clinical trials and is now established as a recommended treatment in the UK National Health Service and elsewhere in the world. Meta-analyses, however, indicate modest effects compared to treatment as usual or comparison therapies such as supportive counselling. Here, we seek to identify factors impacting the effectiveness of CBTp, and avenues for future psychotherapy research that may improve outcomes. 

Method: we outline two recent umbrella reviews and discuss factors likely to impact the effectiveness of CBTp. 

Results: modest effect sizes from meta-analyses mask heterogeneous outcomes, with some people benefiting and others possibly being harmed by therapy. Common factors such as the therapeutic alliance play an important role in determining outcomes but have been largely neglected by CBTp researchers. There is also the promise of improving outcomes by identifying and targeting the psychological mechanisms that either maintain psychotic symptoms (e.g. worry) or are causally implicated (e.g. trauma). 

Conclusions: it is unlikely that everyone with psychosis will be equally responsive to the same therapeutic protocols. We need a new, personalised psychotherapy approach to CBTp research and practice, and can learn from research for anxiety and depression examining predictors of therapeutic response to inform treatment decisions. Precision psychological therapies informed by a combination of individual characteristics, common factors and a focus on specific mechanisms will require new research strategies and are likely to lead to improved outcomes for people with psychosis.

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More information

Accepted/In Press date: 5 September 2023
e-pub ahead of print date: 7 October 2023
Published date: 9 October 2023
Keywords: CBT, CBTp, common factors, meta-analysis, outcomes, psychosis, therapeutic harm, umbrella review

Identifiers

Local EPrints ID: 483109
URI: http://eprints.soton.ac.uk/id/eprint/483109
ISSN: 1476-0835
PURE UUID: 34d7acba-ed8c-4263-94fa-e67f113ff425
ORCID for Katherine Newman-Taylor: ORCID iD orcid.org/0000-0003-1579-7959

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Date deposited: 23 Oct 2023 16:59
Last modified: 18 Mar 2024 03:55

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Author: Richard Bentall

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