Artificial Intelligence, machine learning and deep learning: potential resources for the infection clinician
Artificial Intelligence, machine learning and deep learning: potential resources for the infection clinician
Background: artificial intelligence (AI), machine learning and deep learning (including generative AI) are increasingly being investigated in the context of research and management of human infection.
Objectives: we summarise recent and potential future applications of AI and its relevance to clinical infection practice.
Methods: 1,617 PubMed results were screened, with priority given to clinical trials, systematic reviews and meta-analyses. This narrative review focusses on studies using prospectively collected real-world data with clinical validation, and on research with translational potential, such as novel drug discovery and microbiome-based interventions.
Results: there is some evidence of clinical utility of AI applied to laboratory diagnostics (e.g. digital culture plate reading, malaria diagnosis, antimicrobial resistance profiling), clinical imaging analysis (e.g. pulmonary tuberculosis diagnosis), clinical decision support tools (e.g. sepsis prediction, antimicrobial prescribing) and public health outbreak management (e.g. COVID-19). Most studies to date lack any real-world validation or clinical utility metrics. Significant heterogeneity in study design and reporting limits comparability. Many practical and ethical issues exist, including algorithm transparency and risk of bias.
Conclusions: interest in and development of AI-based tools for infection research and management are undoubtedly gaining pace, although the real-world clinical utility to date appears much more modest.
Artificial intelligence, Clinical decision support systems, Deep learning, Machine learning
287-294
Theodosiou, Anastasia A.
c6e63581-c22d-4a2c-9d14-2e66594eb053
Read, Robert C.
b5caca7b-0063-438a-b703-7ecbb6fc2b51
6 September 2023
Theodosiou, Anastasia A.
c6e63581-c22d-4a2c-9d14-2e66594eb053
Read, Robert C.
b5caca7b-0063-438a-b703-7ecbb6fc2b51
Theodosiou, Anastasia A. and Read, Robert C.
(2023)
Artificial Intelligence, machine learning and deep learning: potential resources for the infection clinician.
Journal of Infection, 87 (4), .
(doi:10.1016/j.jinf.2023.07.006).
Abstract
Background: artificial intelligence (AI), machine learning and deep learning (including generative AI) are increasingly being investigated in the context of research and management of human infection.
Objectives: we summarise recent and potential future applications of AI and its relevance to clinical infection practice.
Methods: 1,617 PubMed results were screened, with priority given to clinical trials, systematic reviews and meta-analyses. This narrative review focusses on studies using prospectively collected real-world data with clinical validation, and on research with translational potential, such as novel drug discovery and microbiome-based interventions.
Results: there is some evidence of clinical utility of AI applied to laboratory diagnostics (e.g. digital culture plate reading, malaria diagnosis, antimicrobial resistance profiling), clinical imaging analysis (e.g. pulmonary tuberculosis diagnosis), clinical decision support tools (e.g. sepsis prediction, antimicrobial prescribing) and public health outbreak management (e.g. COVID-19). Most studies to date lack any real-world validation or clinical utility metrics. Significant heterogeneity in study design and reporting limits comparability. Many practical and ethical issues exist, including algorithm transparency and risk of bias.
Conclusions: interest in and development of AI-based tools for infection research and management are undoubtedly gaining pace, although the real-world clinical utility to date appears much more modest.
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Accepted/In Press date: 12 July 2023
e-pub ahead of print date: 17 July 2023
Published date: 6 September 2023
Additional Information:
Funding Information:
Figures are original and were produced using Mindthegraph.com and Microsoft Office. AT is funded by a Medical Research Council Clinical Research Training Fellowship (MR/V002015/1).
Keywords:
Artificial intelligence, Clinical decision support systems, Deep learning, Machine learning
Identifiers
Local EPrints ID: 484933
URI: http://eprints.soton.ac.uk/id/eprint/484933
ISSN: 0163-4453
PURE UUID: 72ea78ca-8ae6-4f67-a961-42fa6e842c18
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Date deposited: 24 Nov 2023 17:40
Last modified: 11 Dec 2024 03:04
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Author:
Anastasia A. Theodosiou
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