Managing acne vulgaris: an update
Managing acne vulgaris: an update
Acne vulgaris is very common and can have significant negative impact on people. While sometimes a transient problem, acne may persist for many years and often leads to permanent scars or pigment changes. Guidelines unanimously advise topical treatments as first-line, although differ in recommending either topical benzoyl peroxide or topical retinoid (mainly adapalene) alone or in combination. Guidance published by the National Institute for Health and Care Excellence advises counselling patients regarding avoidance of skin irritation when starting topical treatments and promoting adherence (treatments take 6–8 weeks to work). Oral antibiotics are currently overprescribed for acne but have a role when coprescribed with a non-antibiotic topical treatment. Hormonal treatments, such as the combined contraceptive pill, are also effective and there is growing evidence for the use of spironolactone for women with persistent acne. Recent guidance from the Medicines and Healthcare products Regulatory Agency regarding isotretinoin has implications for specialist prescribing and monitoring, and increasing public awareness of potential risks of mental health problems and sexual dysfunction. Although acne is associated with psychiatric disorder, the mental health effects of isotretinoin remain controversial.
acne vulgaris, antimicrobial stewardship, primary health care, skin disease, Antimicrobial Stewardship, Skin diseases, Primary Health Care
6-10
Santer, Miriam
3ce7e832-31eb-4d27-9876-3a1cd7f381dc
Burden-Teh, Esther
9477da01-4541-4ddd-ab0b-7d20973f914b
Ravenscroft, Jane
c04b5faa-bcd0-4d5d-a5ff-44b3342e4ced
27 December 2023
Santer, Miriam
3ce7e832-31eb-4d27-9876-3a1cd7f381dc
Burden-Teh, Esther
9477da01-4541-4ddd-ab0b-7d20973f914b
Ravenscroft, Jane
c04b5faa-bcd0-4d5d-a5ff-44b3342e4ced
Santer, Miriam, Burden-Teh, Esther and Ravenscroft, Jane
(2023)
Managing acne vulgaris: an update.
Drug and Therapeutics Bulletin, 62 (1), .
(doi:10.1136/dtb.2023.000051).
Abstract
Acne vulgaris is very common and can have significant negative impact on people. While sometimes a transient problem, acne may persist for many years and often leads to permanent scars or pigment changes. Guidelines unanimously advise topical treatments as first-line, although differ in recommending either topical benzoyl peroxide or topical retinoid (mainly adapalene) alone or in combination. Guidance published by the National Institute for Health and Care Excellence advises counselling patients regarding avoidance of skin irritation when starting topical treatments and promoting adherence (treatments take 6–8 weeks to work). Oral antibiotics are currently overprescribed for acne but have a role when coprescribed with a non-antibiotic topical treatment. Hormonal treatments, such as the combined contraceptive pill, are also effective and there is growing evidence for the use of spironolactone for women with persistent acne. Recent guidance from the Medicines and Healthcare products Regulatory Agency regarding isotretinoin has implications for specialist prescribing and monitoring, and increasing public awareness of potential risks of mental health problems and sexual dysfunction. Although acne is associated with psychiatric disorder, the mental health effects of isotretinoin remain controversial.
Text
Acne_review_for_DTB_clean_copy
- Accepted Manuscript
Text
6.full
- Version of Record
More information
Accepted/In Press date: 2023
e-pub ahead of print date: 27 December 2023
Published date: 27 December 2023
Additional Information:
Publisher Copyright:
© 2023 BMJ Publishing Group. All rights reserved.
© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Keywords:
acne vulgaris, antimicrobial stewardship, primary health care, skin disease, Antimicrobial Stewardship, Skin diseases, Primary Health Care
Identifiers
Local EPrints ID: 485760
URI: http://eprints.soton.ac.uk/id/eprint/485760
ISSN: 0012-6543
PURE UUID: 57bb9fa7-a191-43c8-bb85-e29114cbfe6a
Catalogue record
Date deposited: 18 Dec 2023 20:35
Last modified: 13 Apr 2024 01:42
Export record
Altmetrics
Contributors
Author:
Esther Burden-Teh
Author:
Jane Ravenscroft
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
