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Machine learning for automated, targeted, phototherapy

Machine learning for automated, targeted, phototherapy
Machine learning for automated, targeted, phototherapy
This work combines two existing technologies to demonstrate the possibility for automated, targeted, phototherapy of psoriasis and other skin conditions: 1) Image-to-image translation via a neural network (NN) as a method of image segmentation. 2) Light control using a digital micromirror device (DMD). With a small dataset of just 104 patient photographs (labeled by expert dermatologists) our NN model was trained to identify regions of psoriasis that required treatment, achieving an average accuracy of 96.6 %. The image output of the NN model was applied to a DMD and precise control over the shape of the illuminated region was demonstrated. In the proposed automated phototherapy device this would target treatment to the affected regions, minimizing exposure of healthy skin and the associated risks of patient harm.
2770-0208
738-750
Praeger, Matthew
84575f28-4530-4f89-9355-9c5b6acc6cac
Scott, Joseph
be3b8f57-ae90-436e-bc83-523c5ba9c3a7
Grant-Jacob, James A.
c5d144d8-3c43-4195-8e80-edd96bfda91b
Barnsley, Josephine
b33a4b93-a4b3-4251-9790-0efccece8691
Niranjan, Mahesan
5cbaeea8-7288-4b55-a89c-c43d212ddd4f
Eason, Robert W.
e38684c3-d18c-41b9-a4aa-def67283b020
Healy, Eugene
400fc04d-f81a-474a-ae25-7ff894be0ebd
Mills, Ben
05f1886e-96ef-420f-b856-4115f4ab36d0
et al.
Praeger, Matthew
84575f28-4530-4f89-9355-9c5b6acc6cac
Scott, Joseph
be3b8f57-ae90-436e-bc83-523c5ba9c3a7
Grant-Jacob, James A.
c5d144d8-3c43-4195-8e80-edd96bfda91b
Barnsley, Josephine
b33a4b93-a4b3-4251-9790-0efccece8691
Niranjan, Mahesan
5cbaeea8-7288-4b55-a89c-c43d212ddd4f
Eason, Robert W.
e38684c3-d18c-41b9-a4aa-def67283b020
Healy, Eugene
400fc04d-f81a-474a-ae25-7ff894be0ebd
Mills, Ben
05f1886e-96ef-420f-b856-4115f4ab36d0

Praeger, Matthew, Scott, Joseph and Grant-Jacob, James A. , et al. (2024) Machine learning for automated, targeted, phototherapy. Optics Continuum, 3 (5), 738-750, [515294]. (doi:10.1364/OPTCON.515294).

Record type: Article

Abstract

This work combines two existing technologies to demonstrate the possibility for automated, targeted, phototherapy of psoriasis and other skin conditions: 1) Image-to-image translation via a neural network (NN) as a method of image segmentation. 2) Light control using a digital micromirror device (DMD). With a small dataset of just 104 patient photographs (labeled by expert dermatologists) our NN model was trained to identify regions of psoriasis that required treatment, achieving an average accuracy of 96.6 %. The image output of the NN model was applied to a DMD and precise control over the shape of the illuminated region was demonstrated. In the proposed automated phototherapy device this would target treatment to the affected regions, minimizing exposure of healthy skin and the associated risks of patient harm.

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Psoriasis__Short_Version__Post_Review__v10__no_tracking - Accepted Manuscript
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More information

Submitted date: 30 January 2024
Accepted/In Press date: 18 April 2024
Published date: 7 May 2024
Additional Information: Publisher Copyright: © 2024, Optica Publishing Group (formerly OSA). All rights reserved.

Identifiers

Local EPrints ID: 490071
URI: http://eprints.soton.ac.uk/id/eprint/490071
ISSN: 2770-0208
PURE UUID: a99374da-98f0-4e60-9a4a-4bde2607da01
ORCID for Matthew Praeger: ORCID iD orcid.org/0000-0002-5814-6155
ORCID for James A. Grant-Jacob: ORCID iD orcid.org/0000-0002-4270-4247
ORCID for Mahesan Niranjan: ORCID iD orcid.org/0000-0001-7021-140X
ORCID for Robert W. Eason: ORCID iD orcid.org/0000-0001-9704-2204
ORCID for Ben Mills: ORCID iD orcid.org/0000-0002-1784-1012

Catalogue record

Date deposited: 14 May 2024 16:41
Last modified: 22 Jun 2024 01:44

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Contributors

Author: Matthew Praeger ORCID iD
Author: Joseph Scott
Author: James A. Grant-Jacob ORCID iD
Author: Josephine Barnsley
Author: Mahesan Niranjan ORCID iD
Author: Robert W. Eason ORCID iD
Author: Eugene Healy
Author: Ben Mills ORCID iD
Corporate Author: et al.

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