Paiva, Ursula, Cortese, Samuele, Flor, Martina, Moncada-Parra, Andrés, Lecumberri, Arturo, Eudave, Luis, Magallón, Sara, García-González, Sara, Sobrino-Morras, Ángel, Piqué, Isabella M., Mestre-Bach, Gemma, Solmi, Marco and Arrondo, Gonzalo (2025) Prevalence of mental disorder symptoms among university students: an umbrella review. Neuroscience and Bioehavioral Reviews, 175, [106244]. (doi:10.1016/j.neubiorev.2025.106244).
Abstract
This umbrella review synthesizes data on the prevalence of mental disorder symptoms among university students worldwide. A systematic search of seven databases (inception–July 23, 2023) followed PRISMA guidelines. We included meta-analyses assessing the prevalence of mental disorder symptoms, evaluating methodological quality with AMSTAR-2. A random-effects meta-analysis was conducted, along with meta-regression and subgroup analyses for moderators (percentage of females, publication date, healthcare-related degrees, COVID-19 pandemic).
We included 1,655 primary studies from 62 meta-analyses, encompassing 8,706,185 participants. AMSTAR-2 ratings classified 35% of meta-analyses as low quality and 65% as critically low. Pooled prevalence estimates were: depression—mild (35.41%, CI=33.9–36.93) and severe (13.42%, CI=8.03–19.92; k=952; n=2,108,813); anxiety—mild (40.21%, CI=37.39–43.07) and severe (16.79%, CI=7.21–29.29; k=433; n=1,579,780); sleep disorders (41.09%, CI=35.7–46.58); eating disorders (17.94%, CI=15.79–20.20); gambling disorder (6.59%, CI=5.52–7.75); post-traumatic stress disorder (25.13%, CI=20.55–30.02); stress (36.34%, CI=29.36–43.62); and suicide-related outcomes (ideation past 12 months: 10.76%, CI=9.53–12.06; lifetime ideation: 20.33%, CI=16.15–24.86; suicide attempt past 12 months: 1.37%, CI=0.67–2.29; lifetime attempt: 3.44%, CI=2.48–4.54). Meta-regression analyses identified statistically significant moderators of prevalence such as healthcare academic degrees and the pandemic in the case of depression and studies with more females in the case of sleep disorders. This is the most comprehensive synthesis on the prevalence of mental disorder symptoms in university students, providing crucial insights for clinicians, policymakers, and stakeholders.
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