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Lamotrigine treatment of mental health problems during the perinatal period

Lamotrigine treatment of mental health problems during the perinatal period
Lamotrigine treatment of mental health problems during the perinatal period

Lamotrigine is beneficial in bipolar disorder and is often prescribed to patients during their period of reproductive potential. We summarise aspects of the pharmacology of lamotrigine, highlight its uses in psychiatric practice, drawing attention to recent findings relating to potential hazards arising from lamotrigine exposure in utero, and make some suggestions for clinical management.

breastfeeding, Lamotrigine, neurodevelopment, pregnancy, teratogenicity
0007-1250
1-3
Austin, Holly A.
800bd07e-f1eb-4393-beab-3cc54eb4992e
Baldwin, David S.
1beaa192-0ef1-4914-897a-3a49fc2ed15e
Austin, Holly A.
800bd07e-f1eb-4393-beab-3cc54eb4992e
Baldwin, David S.
1beaa192-0ef1-4914-897a-3a49fc2ed15e

Austin, Holly A. and Baldwin, David S. (2025) Lamotrigine treatment of mental health problems during the perinatal period. British Journal of Psychiatry, 1-3. (doi:10.1192/bjp.2025.10307).

Record type: Review

Abstract

Lamotrigine is beneficial in bipolar disorder and is often prescribed to patients during their period of reproductive potential. We summarise aspects of the pharmacology of lamotrigine, highlight its uses in psychiatric practice, drawing attention to recent findings relating to potential hazards arising from lamotrigine exposure in utero, and make some suggestions for clinical management.

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Austin-Baldwin-LAM-BJPsych-withTable - CLEAN - Accepted Manuscript
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Accepted/In Press date: 6 May 2025
e-pub ahead of print date: 2 July 2025
Additional Information: Publisher Copyright: © The Author(s), 2025. Published by Cambridge University Press on behalf of Royal College of Psychiatrists.
Keywords: breastfeeding, Lamotrigine, neurodevelopment, pregnancy, teratogenicity

Identifiers

Local EPrints ID: 504333
URI: http://eprints.soton.ac.uk/id/eprint/504333
ISSN: 0007-1250
PURE UUID: 87e997cb-79f6-4da9-b810-a976da12df12
ORCID for David S. Baldwin: ORCID iD orcid.org/0000-0003-3343-0907

Catalogue record

Date deposited: 04 Sep 2025 16:51
Last modified: 05 Sep 2025 01:34

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Contributors

Author: Holly A. Austin

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