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Preliminary considerations on principles for the determination of difficult bubble parameters in situ through Megafrexel high speed photographic observation

Preliminary considerations on principles for the determination of difficult bubble parameters in situ through Megafrexel high speed photographic observation
Preliminary considerations on principles for the determination of difficult bubble parameters in situ through Megafrexel high speed photographic observation
An increasing number of laboratories have the facilities to take high speed
photographs of the pulsations of microbubbles to a degree not previously possible.
Together with the advent of ultrasonic contrast agents which are stable over a long
period, and the use of techniques to locate them within the field of view, these
experimental utilities enable movies to be made of the pulsation of bubbles with much
finer spatial and temporal scales. The quantitative analysis of such movies, if it
occurs, relies on fitting with models that contain several unknowns. This paper
discusses in a preliminary manner how such movies can be interpreted in a way which
reduces the reliance on uncertain fits of models to data, given that the movie provides
basic dynamic information in the form of a time step and a bubble size and shape. If
the driving acoustic field, including its phase with respect to the movie frames, is
recorded, then the movie data can be interpreted directly in terms of key bubble
parameters without fitting.
321
University of Southampton
Leighton, T.G.
3e5262ce-1d7d-42eb-b013-fcc5c286bbae
Leighton, T.G.
3e5262ce-1d7d-42eb-b013-fcc5c286bbae

Leighton, T.G. (2007) Preliminary considerations on principles for the determination of difficult bubble parameters in situ through Megafrexel high speed photographic observation (ISVR Technical Report, 321) Southampton, UK. University of Southampton 27pp.

Record type: Monograph (Project Report)

Abstract

An increasing number of laboratories have the facilities to take high speed
photographs of the pulsations of microbubbles to a degree not previously possible.
Together with the advent of ultrasonic contrast agents which are stable over a long
period, and the use of techniques to locate them within the field of view, these
experimental utilities enable movies to be made of the pulsation of bubbles with much
finer spatial and temporal scales. The quantitative analysis of such movies, if it
occurs, relies on fitting with models that contain several unknowns. This paper
discusses in a preliminary manner how such movies can be interpreted in a way which
reduces the reliance on uncertain fits of models to data, given that the movie provides
basic dynamic information in the form of a time step and a bubble size and shape. If
the driving acoustic field, including its phase with respect to the movie frames, is
recorded, then the movie data can be interpreted directly in terms of key bubble
parameters without fitting.

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Published date: December 2007

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Local EPrints ID: 50507
URI: https://eprints.soton.ac.uk/id/eprint/50507
PURE UUID: 460f9e6c-8444-4ff9-b74f-188bee30ef71
ORCID for T.G. Leighton: ORCID iD orcid.org/0000-0002-1649-8750

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Date deposited: 27 Feb 2008
Last modified: 14 Mar 2019 01:53

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Author: T.G. Leighton ORCID iD

University divisions

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