Microscale computed tomography (µCT) imaging of leak pathways for optimised leak-free 3D printed fluidics
Microscale computed tomography (µCT) imaging of leak pathways for optimised leak-free 3D printed fluidics
3D printing is a highly attractive method for manufacturing micro- and milli-fluidic devices due to fast fabrication times and low barrier to entry. Of the common 3D printing methods, fused filament fabrication (FFF) is the most accessible but is also susceptible to leakages if using default printer settings. Here we combine microscale computed tomography (µCT) X-ray imaging with bulk leak testing to understand the fundamental structural reasons why leakages occur and the effect of optimising print parameters. In contrast to previous recommendations, we show that the amount of infill can be reduced as required, with print bodies being intrinsically porous regardless of infill. Instead we find it is solely channel wall quality that determines whether leaks will occur. In keeping with previous reports, we see that smaller layer heights (<0.1 mm) and increased flow rates (>100 % compared to recommended rate) are key to preventing leakage and show this is because of their positive effect on channel wall formation. A key consequence of being able to maintain channel integrity whilst using low infill values is that print times and material costs can be greatly reduced (over 50 % time and cost savings for the test pieces used here) without compromising device performance.
14130-14137
Leeder, Rowan
d83c2aef-5049-48a1-9ee7-b76f9a37e4d3
Rankin, Kathryn E.
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Nightingale, Adrian
4b51311d-c6c3-40d5-a13f-ab8917031ab3
24 October 2025
Leeder, Rowan
d83c2aef-5049-48a1-9ee7-b76f9a37e4d3
Rankin, Kathryn E.
d9516566-0ad8-473d-b99b-4683c663a2b7
Nightingale, Adrian
4b51311d-c6c3-40d5-a13f-ab8917031ab3
Leeder, Rowan, Rankin, Kathryn E. and Nightingale, Adrian
(2025)
Microscale computed tomography (µCT) imaging of leak pathways for optimised leak-free 3D printed fluidics.
ACS Applied Polymer Materials, 7 (21), .
(doi:10.1021/acsapm.5c02274).
Abstract
3D printing is a highly attractive method for manufacturing micro- and milli-fluidic devices due to fast fabrication times and low barrier to entry. Of the common 3D printing methods, fused filament fabrication (FFF) is the most accessible but is also susceptible to leakages if using default printer settings. Here we combine microscale computed tomography (µCT) X-ray imaging with bulk leak testing to understand the fundamental structural reasons why leakages occur and the effect of optimising print parameters. In contrast to previous recommendations, we show that the amount of infill can be reduced as required, with print bodies being intrinsically porous regardless of infill. Instead we find it is solely channel wall quality that determines whether leaks will occur. In keeping with previous reports, we see that smaller layer heights (<0.1 mm) and increased flow rates (>100 % compared to recommended rate) are key to preventing leakage and show this is because of their positive effect on channel wall formation. A key consequence of being able to maintain channel integrity whilst using low infill values is that print times and material costs can be greatly reduced (over 50 % time and cost savings for the test pieces used here) without compromising device performance.
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CT_3DP_leak_paper_postSecondReviewFinalisedWithKeywords
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microscale-computed-tomography-(μct)-imaging-of-leak-pathways-for-optimized-leak-free-3d-printed-fluidics
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Accepted/In Press date: 16 October 2025
Published date: 24 October 2025
Identifiers
Local EPrints ID: 506846
URI: http://eprints.soton.ac.uk/id/eprint/506846
ISSN: 2637-6105
PURE UUID: ac463953-92fd-4188-8937-27dc6e06b1d1
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Date deposited: 19 Nov 2025 17:31
Last modified: 20 Nov 2025 02:45
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Author:
Rowan Leeder
Author:
Kathryn E. Rankin
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