Items where Division is "Current Faculties > Faculty of Engineering and Physical Sciences > Chemistry and Chemical Engineering > Chemical Biology, Diagnostics and Therapeutics
Chemistry and Chemical Engineering > Chemical Biology, Diagnostics and Therapeutics" and Year is 2022
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Number of items: 20.
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A new phosphoramidite enables orthogonal double labelling to form combination oligonucleotide probes - Chunsen Bai, Piotr Klimkowski, Cheng Jin, Jagannath Kuchlyan, Afaf El-Sagheer and Tom Brown
Type: Article
| 2022
| Item not available on this server.
An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides, - Ysobel Baker, Cameron Thorpe, Jinfeng Chen, Laura M Poller, Pawan Kumar, Wooi F Lim, Lillian Lie, Graham McClorey, Sven Epple, Daniel Singleton, Michael A McDonough, Jack S. Hardwick, Kirsten E. Christensen, Matthew J.A. Wood, James P. Hall, Afaf H El-Sagheer and Tom Brown
Type: Article
| 2022
Selected applications of spirocycles in medicinal chemistry - Matthias G.J. Baud
Type: Book Section
| 2022
| Wiley
| Item not available on this server.
Rationally designed helical peptidomimetics disrupt α-synuclein fibrillation - Clementine, Ella Bavinton, Rebecca Sternke-Hoffmann, Tohru Yamashita, Peter Knipe, Andrew D. Hamilton, Jinghui Luo and Sam Thompson
Type: Article
| 2022
Anionic self-assembling supramolecular enhancers of antimicrobial efficacy against gram-negative bacteria - Jessica E. Boles, George Williams, Nyasha Allen, Lisa J. White, Kira L. F. Hilton, Precious I. A. Popoola, Daniel P. Mulvihill and Jennifer Hiscock
Type: Article
| 2022
Pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosis - Christopher J. Brereton, Liudi Yao and Elizabeth R. Davies
Type: Article
| 2022
| Item availability restricted.
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ACCEPT - combining acalabrutinib with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) for Diffuse Large B-cell Lymphoma (DLBCL): study protocol for a Phase Ib/II open-label non-randomised clinical trial - Andrew Davies, Sharon Barrans, Cathy Burton, Katy Mercer, Joshua Caddy, Fay Chinnery, Laura Day, Diana Fernando, Kirit Ardeshna, Graham Collins, John Radford, Simon Rule, Andrew Mcmillan, Peter Johnson and Gareth Griffiths
Type: Article
| 2022
Advancements in antimicrobial nanoscale materials and self-assembling systems - Jack A. Doolan, George T. Williams, Kira L. F. Hilton, Rajas Chaudhari, John S. Fossey, Benjamin T. Goult and Jennifer Hiscock
Type: Article
| 2022
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Type: Article
| 2022
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Advancements in the characterisation of oligonucleotides by high performance liquid chromatography-mass spectrometry in 2021: A short review - Fabien Hannauer, Rachelle Black, Andrew D. Ray, Eugen Stulz, G. John Langley and Stephen W. Holman
Type: Review
| 2022
Enhanced Raman techniques for infection diagnostics - Niall Hanrahan, Adam P. Lister, Callum J. Highmore, Leena Rajith, Ekaterina Avershina, Jawad Ali, Rafi Ahmad, Jeremy S. Webb and Sumeet Mahajan
Type: Conference or Workshop Item
| 2022
| SPIE
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Characterizing the beta-catenin interactome using inhibitor screens and novel interaction proteomics techniques - S. John, R. Ewing, M. Baud, N. Divecha and P. Skipp
Type: Meeting abstract
| 2022
| Item not available on this server.
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Type: Dataset
| 2022
| University of Southampton
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Multi-excitation raman spectroscopy complements whole genome sequencing for rapid detection of bacterial infection and resistance in WHO priority pathogens - Adam Lister, Ekaterina Avershina, George Devitt, Niall Hanrahan, Callum Highmore, Jeremy Webb, Fredrik Muller, Sumeet Mahajan, Department of Biotechnology Inland Norway University of Applied Norway and Shaikh Rafi Ahamed
Type: Article
| 2022
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Biophysical survey of small-molecule β-catenin inhibitors: a cautionary tale - Michael, Arron McCoy, Dominique Spicer, Neil J. Wells, Kurt Hoogewijs, Marc Fiedler and Matthias G.J. Baud
Type: Article
| 2022
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Persistent homology analysis distinguishes pathological bone microstructure in non-linear microscopy images - Ysanne Pritchard, Aikta Sharma, Claire Clarkin, Helen Ogden, Sumeet Mahajan and Ruben J Sanchez-Garcia
Type: Article
| 2022
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Discovery of Nanomolar-Affinity Pharmacological Chaperones Stabilizing the Oncogenic p53 Mutant Y220C - Joseph Richard Stephenson Clarke, Leon R Douglas, Patrick Duriez, Dimitrios-Ilias Balourdas, Andreas C. Joerger, Raniya Khadiullina, Emil Bulatov and Matthias G.J. Baud
Type: Article
| 2022
Covalently attached intercalators restore duplex stability and splice-switching activity to triazole-modified oligonucleotides. - Anna Sysko, Ysobel Baker, Graham McClorey, Matthew J.A. Wood, Sabine Fenner, Glynn Williams, Afaf H El-Sagheer and Tom Brown
Type: Article
| 2022
| Item not available on this server.
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Multi-excitation Raman spectroscopy for label-free, strain-level characterization of bacterial pathogens in artificial sputum media - Jeremy Webb, Adam Lister, Callum Highmore, Niall Hanrahan, James, Arthur Read, Alasdair, Peter Stuart Munro, Samuel Tan, Raymond Allan, Saul Faust and Sumeet Mahajan
Type: Article
| 2022
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1840-nm femtosecond thulium fiber laser system for label-free third-harmonic generation microscopy - L. Xu, D. Xu, K.N. Bourdakos, P.B. Johnson, A. Crisford, I. Abughazaleh, P. Srisamran, Q. Fu, S. Mahajan and D. J. Richardson
Type: Book Section
| 2022
| IEEE
| Item not available on this server.