Items where Division is "Current Faculties > Faculty of Medicine > NIHR Southampton Clinical Research Facility" and Year is 2022
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Number of items: 51.
Type: Article
| 2022
Public attitudes to a human challenge study with SARS-CoV-2: a mixed-methods study - Caroline Barker, Katharine Collet, Diane Gbesemete, Maria Piggin, Daniella Watson, Philippa Pristerà, Wendy Lawrence, Emma Smith, Michael Bahrami-Hessari, Halle Johnson, Katherine Baker, Ambar Qavi, Carmel McGrath, Christopher Chiu, Robert C Read and Helen Ward
Type: Article
| 2022
Impact of the COVID-19 pandemic on prescription refills for immune-mediated inflammatory disorders: a time series analysis (Jan 2019 to Jan 2021) using the English Prescribing Dataset - Ravina Barrett, Robert Barrett, Sharon Xiaowen Lin, David Culliford, Simon Fraser and Christopher Edwards
Type: Article
| 2022
The assessment of future RSV immunizations: How to protect all infants? - Louis Bont, Catherine Weil Olivier, Egbert Herting, Susanna Esposito, Jose Antonio Navarro Alonso, Federico Lega, Silke Mader, Ichiro Morioka, Kunling Shen, George A. Syrogiannopoulos, Saul N. Faust and Elena Bozzola
Type: Article
| 2022
Immunocompromised children and young people are at no increased risk of severe COVID-19 - H. Chappell, R. Patel, C. Driessens, A.W. Tarr, W.l. Irving, P.J. Tighe, H.J. Jackson, T. Harvey-cowlishaw, L. Mills, M. Shaunak, D. Gbesemete, A. Leahy, J.S. Lucas, S.N. Faust and H. De Graaf
Type: Article
| 2022
Changes in serotype prevalence of Streptococcus pneumoniae in Southampton, UK between 2006 and 2018 - David W. Cleary, Jessica Jones, Rebecca A. Gladstone, Karen L. Osman, Vanessa T. Devine, Johanna M Jefferies, Stephen D. Bentley, Saul N Faust and Stuart C. Clarke
Type: Article
| 2022
Severe COVID‐19 pneumonia in an intensive care setting and comparisons with historic severe viral pneumonia due to other viruses - Kiran Dadhwal, Rosalind Stonham, Hannah Breen, Stephen Poole, Kordo Saeed and Ahilanandan Dushianthan
Type: Article
| 2022
Neisseria lactamica controlled human infection model - Adam P Dale, Diane F Gbesemete, Robert C Read and Jay R Laver
Type: Book Section
| 2022
| Humana New York
Effect of colonisation with Neisseria lactamica on cross-reactive anti-meningococcal B-cell responses: a randomised, controlled, human infection trial - Adam P Dale, Anastasia A Theodosiou, Diane F Gbesemete, Jonathan M Guy, Eleanor F Jones, Alison R Hill, Muktar M Ibrahim, Hans de Graaf, Muhammad Ahmed, Saul N Faust, Andrew R Gorringe, Marta E Polak, Jay R Laver and Robert C Read
Type: Article
| 2022
| Item not available on this server.
Characterisation of SARS-CoV-2 genomic variation in response to molnupiravir treatment in the AGILE Phase IIa clinical trial - I'ah Donovan-Banfield, Rebekah Penrice-Randal, Hannah Goldswain, Aleksandra M Rzeszutek, Jack Pilgrim, Katie Bullock, Geoffrey Saunders, Josh Northey, Xiaofeng Dong, Yan Ryan, Helen Reynolds, Michelle Tetlow, Lauren E Walker, Richard FitzGerald, Colin Hale, Rebecca Lyon, Christie Woods, Shazaad Ahmad, Dennis Hadjiyiannakis, Jimstan Periselneris, Emma Knox, Calley Middleton, Lara Lavelle-Langham, Victoria Shaw, William Greenhalf, Thomas Edwards, David G Lalloo, Christopher J Edwards, Alistair C Darby, Miles W Carroll, Gareth Griffiths, Saye H Khoo, Julian A Hiscox and Thomas Fletcher
Type: Article
| 2022
Parental concern for clinically vulnerable child during first 18 months of the COVID pandemic - Corine Driessens, Lynne Mills, David Culliford, Ravin Patel, Emma Lee, Diane Gbesemete, Harry Chappell, Meera Shaunak, Saul N. Faust and Hans De Graaf
Type: Article
| 2022
Immunosuppressed children and young people, psychosocial wellbeing, and the COVID-19 pandemic: a prospective cohort study - Corine Driessens, Lynne Mills, Ravin Patel, David Culliford, Diane Gbesemete, Emma Lee, Meera Shaunak, Harry Chappell, Saul N. Faust and Hans Graaf
Type: UNSPECIFIED
| 2022
Type: Article
| 2022
Lactamica 3 Clinical Study Protocol V5.0, 26.04.2017: A human controlled infection study to assess colonisation and immunogenicity following nasal inoculation with Neisseria lactamica with eradication on day 4 or 14 - Saul Faust, Diane, Frances Gbesemete, Hans De Graaf and Robert Read
Type: Monograph
| 2022
| University of Southampton
Persistently normal blood tests in patients taking methotrexate for RA or azathioprine for IBD: a retrospective cohort study - Simon Fraser, Sharon Lin, Matt Stammers, David Culliford, Kinda Ibrahim, James Batchelor and Paul Roderick
Type: Article
| 2022
A patient with multilocus imprinting disturbance involving hypomethylation at 11p15 and 14q32, and phenotypic features of Beckwith‐Wiedemann and Temple syndromes - Sarah E. Grosvenor, Justin H. Davies, Margaret Lever, Julie Sillibourne, Deborah J. G. Mackay and I. Karen Temple
Type: Article
| 2022
Efficacy and safety of a recombinant plant-based adjuvanted Covid-19 vaccine - Karen J Hager, Gonzalo Pérez Marc, Philipe Gobeil, Ricardo S Diaz, Gretchen Heizer and Conrado Llapur
Type: Article
| 2022
Efficacy, safety, and immunogenicity of a booster regimen of Ad26.COV2.S vaccine against COVID-19 (ENSEMBLE2): results of a randomised, double-blind, placebo-controlled, phase 3 trial - Karin Hardt, An Vandebosch, Jerald Sadoff, Mathieu Le Gars, Carla Truyers, David Lowson, Ilse Van Dromme, Johan Vingerhoets, Tobias Kamphuis, Gert Scheper, Javier Ruiz-Guiñazú, Saul N Faust, Christoph D Spinner, Hanneke Schuitemaker, Johan Van Hoof, Macaya Douoguih and Frank Struyf
Type: Article
| 2022
Type: Article
| 2022
Body Mass Index and clinical outcome of severe COVID-19 patients with acute hypoxic respiratory failure: unravelling the “obesity paradox” phenomenon - Michael Jennings, Maria Burova, Laura G. Hamilton, Elsie Hunter, Clare Mordena, Ryan Beecham, Darshni Pandya, Helen Moyses, Kordo Saeed, Paul Afolabi, Philip Calder and Ahilanandan Dushianthan
Type: Article
| 2022
Vaccination in pregnancy against pertussis: A consensus statement on behalf of the global pertussis initiative - Christine E Jones, Bahaa Abu-Raya, Kevin Forsyth, Scott A. Helperin, Kirsten Maertens, Chistine E. Jones, Ulrich Heininger, Daniela Hozbor, Carl Heinz Wirsing von König and Amar J. Chitkara
Type: Review
| 2022
Managing challenges in congenital CMV: current thinking - Christine E Jones, Heather Bailey, Alasdair Bamford, Anna Calvert, Robert B. Dorey, Simon B. Drysdale, Asma Khalil, Paul T. Heath, Hermione Lyall, Kate Monica Isabel Ralph, Shari Sapuan, Tushna Vandrevala, Simone Walter, Elizabeth Whittaker and Sharon Wood
Type: Article
| 2022
Immunity debt and unseasonal childhood respiratory viruses - Christine E. Jones
Type: Article
| 2022
Anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodies: incidence using different testing criteria, and case series - Vikram M K Joseph, Emily C Rose, Christopher J Edwards, Mark Lloyd, Soha K Amar, Rachel D Wheeler, Tamara Forster, Karen A Smith, Efrem Eren, Rod Hughes, Vijay Hajela and Patrick D W Kiely
Type: Article
| 2022
| Item not available on this server.
Molnupiravir versus placebo in unvaccinated and vaccinated patients with early SARS-CoV-2 infection in the UK (AGILE CST-2): a randomised, placebo-controlled, double-blind, phase 2 trial - Saye H. Khoo, Richard FitzGerald and Geoffrey Saunders
Type: Article
| 2022
Safety and immunogenicity of the inactivated whole-virus adjuvanted COVID-19 vaccine VLA2001 - Rajeka Lazarus, Christian Taucher, Claire Brown, Irena Corbic, Leon Danon and Katrin Dubischar
Type: Article
| 2022
Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine in children aged 6-17 years: a preliminary report of COV006, a phase 2 single-blind, randomised, controlled trial - Grace Li, Federica Cappuccini, Natalie G Marchevsky, Parvinder K Aley, Robert Aley, Rachel Anslow, Xinxue Liu, Teresa Lambe and Andrew J Pollard
Type: Article
| 2022
Immune responses to SARS-CoV-2 variants after two and three doses of vaccine in B-cell malignancies: UK PROSECO Study - Sean H. Lim, Beth Stuart, Debora Joseph-Pietras, Marina Johnson, Nicola Campbell, Adam Kelly, Danielle Jeffrey, Anna H Turaj, Kate Rolfvondenbaumen, Celine Galloway, Thomas Wynn, Adam R. Coleman, Benjamin Ward, Karen Long, Helen Coleman, Carina Mundy, Andrew T. Bates, Diana Ayres, Robert Lown, Janlyn Falconer, Oliver Brake, James Batchelor, Victoria Willimott, Anna Bowzyk Al-Naeeb, Lisa Robinson, Ann O'Callaghan, Graham P Collins, Tobias Menne, Saul N Faust, Christopher P Fox, Matthew Ahearne, Peter W M Johnson, Andrew J Davies and David Goldblatt
Type: Article
| 2022
Antibiotics for lower respiratory tract infection in children presenting in primary care (ARTIC-PC): the predictive value of molecular testing - Paul Little, Robert C. Read, Taeko Becque, Nick A. Francis, Alastair D. Hay, Beth Stuart, Gilly O'Reilly, Natalie Thompson, Kerenza Hood, Saul Faust, Kay Wang, Michael Moore and Theo Verheij
Type: Article
| 2022
Persistence of immunogenicity after seven COVID-19 vaccines given as third dose boosters following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK: three month analyses of the COV-BOOST trial - Xinxue Liu, Alasdair P S Munro, Shuo Feng, Leila Janani, Parvinder K Aley, Gavin Babbage, Katrina Cathie, Daniel R Owens, Robert C Read and Saul N Faust
Type: Article
| 2022
Compassionate use of Pulmonary Vasodilators in Acute Severe Hypoxic Respiratory Failure due to COVID-19 - Lewis Matthews, Laurence Baker, Matteo Ferrari, Weronika Sanchez, John Pappachan, Mike Pw Grocott, Ahilanandan Dushianthan, Thomas Wilkinson, Hannah Burke, Anna Freeman, Michael Celinski, Saul Faust, Gareth Thomas and Christopher Kipps
Type: Article
| 2022
Experiences of pregnant women and healthcare professionals of participating in a digital antenatal CMV education intervention - Amy Montague, Tushna Vandrevala, Anna Calvert, L. Ling Yeh, Caroline Star, Asma Khalil, Paul Griffiths, Paul T. Heath and Christine E. Jones
Type: Article
| 2022
Preparing for disease X: ensuring vaccine equity for pregnant women in future pandemics - Flor M. Munoz, Clare L. Cutland, Christine E. Jones, Beate Kampmann, Asma Khalil, Esperança Sevene, Andy Stergachis, Geeta K. Swamy, Gerald Voss and Ajoke Sobanjo-ter Meulen
Type: Article
| 2022
Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial - Alasdair P S Munro, Shuo Feng, Leila Janani, Victoria Cornelius, Parvinder K Aley, Gavin Babbage and Saul N Faust
Type: Article
| 2022
Durability of ChAdOx1 nCoV-19 vaccination in people living with HIV - Ane Ogbe, Matthew Pace, Mustapha Bittaye, Timothy Tipoe, Sandra Adele, Jasmini Alagaratnam, Parvinder K Aley, M Azim Ansari, Anna Bara, Samantha Broadhead, Anthony Brown, Helen Brown, Federica Cappuccini, Paola Cinardo, Wanwisa Dejnirattisai, Katie J Ewer, Henry Fok, Pedro M Folegatti, Jamie Fowler, Leila Godfrey, Anna L Goodman, Bethany Jackson, Daniel Jenkin, Mathew Jones, Stephanie Longet, Rebecca A Makinson, Natalie G Marchevsky, Moncy Mathew, Andrea Mazzella, Yama F Mujadidi, Lucia Parolini, Claire Petersen, Emma Plested, Katrina M Pollock, Thurkka Rajeswaran, Maheshi N Ramasamy, Sarah Rhead, Hannah Robinson, Nicola Robinson, Helen Sanders, Sonia Serrano, Tom Tipton, Anele Waters, Panagiota Zacharopoulou, Eleanor Barnes, Susanna Dunachie, Philip Goulder, Paul Klenerman, Gavin R Screaton, Alan Winston, Adrian Vs Hill, Sarah C Gilbert, Miles Carroll, Andrew J Pollard, Sarah Fidler, Julie Fox, Teresa Lambe and John Frater
Type: Article
| 2022
Point-of-care testing in Paediatric settings in the UK and Ireland: a cross-sectional study - Meenu Pandey, Mark D Lyttle, Katrina Cathie, Alasdair Munro, Thomas Waterfield and Damian Roland
Type: Article
| 2022
Safety and immunogenicity of a self-amplifying RNA vaccine against COVID-19: COVAC1, a phase I, dose-ranging trial - Katrina M Pollock, Hannah M Cheeseman, Alexander J Szubert, Vincenzo Libri, Marta Boffito and David Owen
Type: Article
| 2022
Paediatric health-related quality of life in congenital cytomegalovirus - Kate Monica Isabel Ralph, Kim Bull, Caroline Trotter, Sharon Wood and Christine E Jones
Type: Article
| 2022
Community seroprevalence of SARS-CoV-2 in children and adolescents in England, 2019-2021 - Helen Ratcliffe, K.S. Tiley, Nick Andrews, Gayatri Amirthalingam, I. Vichos, E. Morey, N.L. Douglas, S. Marinou, Emma Plested, Parvinder Aley, Eva P. Galiza, Saul N. Faust, S. Hughes, Clare S. Murray, Marion Roderick, Fiona Shackley, Sam J. Oddie, Tim Lees, D.P.J. Turner, M. Raman, Stephen Owens, Paul Turner, H. Cockerill, J. Lopez Bernal, E. Linley, Ray Borrow, Kevin Brown, Mary Elizabeth Ramsay, M. Voysey and Matthew D. Snape
Type: Article
| 2022
An observational, cohort, multi-centre, open label phase IV extension study comparing preschool DTAP-IPV booster vaccine responses in children whose mothers were randomised to one of two pertussis-containing vaccines or received no pertussis-containing vaccine in Pregnancy in England - Shari Sapuan, Nick J. Andrews, Bassam Hallis, Laura Hole, Christine E Jones, Mary Matheson, Elizabeth Miller, Matthew D. Snape and Paul T. Heath
Type: Article
| 2022
A systematic review and meta-analysis of the prevalence of human cytomegalovirus shedding in seropositive pregnant women - Shari Sapuan, Anastasia Theodosiou, Blair L. Strang, Paul T. Heath and Christine E. Jones
Type: Review
| 2022
Effect of priming interval on reactogenicity, peak immunological response, and waning after homologous and heterologous COVID-19 vaccine schedules: exploratory analyses of Com-COV, a randomised control trial - Robert H. Shaw, Xinxue Liu, Arabella S.V. Stuart, Melanie Greenland, Parvinder K. Aley and Nick J. Andrews
Type: Article
| 2022
Immunogenicity, safety, and reactogenicity of heterologous COVID-19 primary vaccination incorporating mRNA, viral-vector, and protein-adjuvant vaccines in the UK (Com-COV2): a single-blind, randomised, phase 2, non-inferiority trial - Arabella S V Stuart, Robert H Shaw, Xinxue Liu, Melanie Greenland, Parvinder K Aley and Nick J Andrews
Type: Article
| 2022
Phase 1/2a Safety and Immunogenicity of an Adenovirus 26 Vector Respiratory Syncytial Virus (RSV) Vaccine Encoding Prefusion F in Adults 18–50 Years and RSV-Seropositive Children 12–24 Months - Arabella S.V. Stuart, Miia Virta, Kristi Williams, Ilkka Seppa, Robyn Hartvickson, Melanie Greenland, Edmund Omoruyi, Arangassery Rosemary Bastian, Wouter Haazen, Nadine Salisch, Efi Gymnopoulou, Benoit Callendret, Saul N Faust, Matthew D Snape and Esther Heijnen
Type: Article
| 2022
Comparison of UK paediatric SARS-CoV-2 admissions across the first and second pandemic waves - Olivia V. Swann, Louisa Pollock, Karl A. Holden, Alasdair P.S. Munro, Aisleen Bennett, Thomas C. Williams and Malcolm G. Semple
Type: Article
| 2022
HIV-associated alterations of the biophysical features of maternal antibodies correlate with their reduced transfer across the placenta - Sean A. Taylor, Shilpee Sharma, Christopher A. L. Remmel, Beth Holder, Christine E. Jones, Arnaud Marchant and Margaret E. Ackerman
Type: Article
| 2022
Controlled human infection with Neisseria lactamica in late pregnancy to measure horizontal transmission and microbiome changes in mother-neonate pairs: A single-arm interventional pilot study protocol - Anastasia A Theodosiou, Jay R Laver, Adam P Dale, David W Cleary, Christine E Jones and Robert C Read
Type: Article
| 2022
Safety, immunogenicity, and efficacy of a COVID-19 vaccine (NVX-CoV2373) co-administered with seasonal influenza vaccines: an exploratory substudy of a randomised, observer-blinded, placebo-controlled, phase 3 trial - Seth Toback, Eva Galiza, Catherine Cosgrove, James Galloway, Anna L. Goodman, Pauline A. Swift, Sankarasubramanian Rajaram, Alison Graves-Jones, Jonathan Edelman, Fiona Burns, Angela M. Minassian, Iksung Cho, Lakshmi Kumar, Joyce S. Plested, E. Joy Rivers, Andreana Robertson, Filip Dubovsky, Greg Glenn and Paul T. Heath
Type: Article
| 2022
Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial - Cherry-Ann Waldron, Emma Thomas-Jones, Jolanta Bernatoniene, Lucy Brookes-Howell, Saul N Faust, Debbie Harris, Lucy Hinds, Kerenza Hood, Chao Huang, Céu Mateus, Philip Pallmann, Sanjay Patel, Stéphane Paulus, Matthew Peak, Colin Powell, Jennifer Preston and Enitan D Carrol
Type: Article
| 2022
Multi-excitation Raman spectroscopy for label-free, strain-level characterization of bacterial pathogens in artificial sputum media - Jeremy Webb, Adam Lister, Callum Highmore, Niall Hanrahan, James, Arthur Read, Alasdair, Peter Stuart Munro, Samuel Tan, Raymond Allan, Saul Faust and Sumeet Mahajan
Type: Article
| 2022
Multicenter Randomized Trial of Methylprednisolone vs. Intravenous Immunoglobulins to Treat the Pediatric Inflammatory Multisystem Syndrome-Temporally Associated With SARS-CoV-2 (PIMS-TS): Protocol of the Swissped RECOVERY Trial - Tatjana Welzel, Nina Schöbi, Maya C André, Douggl G N Bailey, Geraldine Blanchard-Rohner and Michael Buettcher
Type: Article
| 2022