Items where Division is "Faculties (pre 2018 reorg) > Faculty of Medicine (pre 2018 reorg) > Clinical & Experimental Sciences (pre 2018 reorg)
Current Faculties > Faculty of Medicine > Clinical and Experimental Sciences > Clinical & Experimental Sciences (pre 2018 reorg)
Clinical and Experimental Sciences > Clinical & Experimental Sciences (pre 2018 reorg)" and Year is 2021
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Number of items: 48.
Type: Article
| 2021
Type: Article
| 2021
Peripheral airways type 2 inflammation, neutrophilia and microbial dysbiosis in severe asthma - Adnan Azim, Ben Green, Laurie Lau, Hitasha Rupani, Nivenka Jayasekera, Kenneth Bruce and Peter Howarth
Type: Article
| 2021
Clinical evaluation of type 2 disease status in a real-world population of difficult to manage asthma using historic Electronic Health Care Records of Blood Eosinophil counts - Adnan Azim, Colin Newell, Clair Barber, Matthew Harvey, Deborah Knight, Anna Freeman, Wei Chern Gavin Fong, Paddy Dennison, Hans Michael Haitchi, Ratko Djukanovic, Ramesh Kurukulaaratchy and Peter Howarth
Type: Article
| 2021
Sputum processing by mechanical dissociation: a rapid alternative to traditional sputum assessment approaches - Clair Barber, Laurie Lau, Jonathan Ward, Thomas Daniels, Alastair Watson, Karl J. Staples, Thomas Wilkinson and Peter Howarth
Type: Article
| 2021
The locus coeruleus in aging and Alzheimer’s Disease: a postmortem and brain imaging review - Rebecca C Beardmore, Ruihua Hou, Angela Darekar, Clive Holmes and Delphine Boche
Type: Review
| 2021
A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection - Cornelia Blume, Claire L. Jackson, Cosma Mirella Spalluto, Jelmer Legebeke, Liliya Nazlamova, Franco Conforti, Jeanne Marie Perotin, Martin Frank, John Butler, Max Crispin, Janice Coles, James Thompson, Robert A. Ridley, Lareb S.N. Dean, Matthew Loxham, Stephanie Reikine, Adnan Azim, Kamran Tariq, David A. Johnston, Paul J. Skipp, Ratko Djukanovic, Diana Baralle, Christopher J. McCormick, Donna E. Davies, Jane S. Lucas, Gabrielle Wheway and Vito Mennella
Type: Article
| 2021
Neuraminidase inhibitor use in adults presenting to hospital with suspected influenza: a questionnaire-based survey of practice among hospital physicians - Nathan Brendish, Ahalya K Malachira, Patrick J Lillie and Tristan Clark
Type: Article
| 2021
Incidence of sight-threatening diabetic retinopathy in an established urban screening programme: an 11-year cohort study - Christopher P. Cheyne, Philip I. Burgess, Deborah M. Broadbent, Marta García-Fiñana, Irene M. Stratton, Ticiana Criddle, Amu Wang, Ayesh Alshukri, Mehrdad M. Rahni, Pilar Vazquez-Arango, Jiten P. Vora and Simon P. Harding
Type: Article
| 2021
Type: Dataset
| 2021
| University of Southampton
The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci - Stuart Clarke
Type: Article
| 2021
Immune environment of the brain in schizophrenia and during the psychotic episode: a human post-mortem study - Livia De Picker, Gerardo Mendez-Victoriano, Rhys Richards, Alexander Gorvett, Simeon Lyons, George Buckland, Tommaso Tofani, Jeanette Norman, David Chatelet, James Nicoll and Delphine Boche
Type: Review
| 2021
Human intestinal macrophages are involved in the pathology of both ulcerative colitis and Crohn disease - Suranga Dharmasiri, Eva M. Garrido-Martin, Richard, James Harris, Adrian C. Bateman, Jane E. Collins, J.R. Fraser Cummings and Tilman Sanchez-Elsner
Type: Article
| 2021
Using explainable machine learning to characterise data drift and detect emergent health risks for emergency department admissions during COVID-19 - Christopher Duckworth, Francis P. Chmiel and Dan K. Burns
Type: Article
| 2021
Type: Article
| 2021
| Item not available on this server.
Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy - Simon Eschweiler, James Clarke, Ciro Ramírez-suástegui, Bharat Panwar, Ariel Madrigal, Serena J. Chee, Ioannis Karydis, Edwin Woo, Aiman Alzetani, Somaia Elsheikh, C. J. Hanley, G. J. Thomas, Peter S. Friedmann, Tilman Sanchez-elsner, Ferhat Ay, Christian H. Ottensmeier and Pandurangan Vijayanand
Type: Article
| 2021
Asthma did not increase in-hospital Covid-19 related mortality in a tertiary UK hospital - Wei Chern Gavin Fong, Florina Borca, Hang Phan, Helen E Moyses, Paddy Dennison, Ramesh J Kurukulaaratchy and Hans Michael Haitchi
Type: Letter
| 2021
Composite type-2 biomarker strategy versus a symptom-risk-based algorithm to adjust corticosteroid dose in patients with severe asthma: a multicentre, single-blind, parallel group, randomised controlled trial - Liam G Heaney, John Busby, Catherine E Hanratty, Ratko Djukanovic, Ashley Woodcock, Samantha M Walker, Timothy C Hardman, Joseph R Arron, David F Choy, Peter Bradding, Christopher E Brightling, Rekha Chaudhuri, Douglas C Cowan, Adel H Mansur, Stephen J Fowler, Robert M Niven, Peter H Howarth, James L Lordan, Andrew Menzies-Gow, Tim W Harrison, Douglas S Robinson, Cecile T J Holweg, John G Matthews and Ian D Pavord
Type: Article
| 2021
Micro RNA targets in HIV latency: Insights into novel layers of latency control - Ashley I. Heinson, Jeongmin Woo, Amey Mukim, Cory H. White, Bastiaan Moesker, Alberto Bosque, Celsa A. Spina, Christopher H. Woelk, Ben D. Macarthur and Nadejda Beliakova-Bethell
Type: Article
| 2021
| Item availability restricted.
Microbial keratitis-the true costs of a silent pandemic? - Parwez Hossain
Type: Editorial
| 2021
Reducing the burden of ocular surface disease with serum eye drops - Parwez Hossain
Type: Editorial
| 2021
| Item not available on this server.
The Effect of Systemic Levels of TNF-alpha and Complement Pathway Activity on Outcomes of VEGF Inhibition in Neovascular AMD - Adnan Khan, Charles Pierce, Gabriella De Salvo, Helen Griffiths, Marie Nelson, Angela Cree, Geeta Menon and Andrew Lotery
Type: Article
| 2021
Type: Dataset
| 2021
| University of Southampton
New Real-World Insights Into Severe Asthma: All About the Eosinophil? - Ramesh J Kurukulaaratchy and Heena Mistry
Type: Editorial
| 2021
| Item not available on this server.
A recombinant commensal bacteria elicits heterologous antigen-specific immune responses during pharyngeal carriage - Jay R Laver, Diane Gbesemete, Adam P Dale, Zoe C Pounce, Carl N Webb, Eleanor F Roche, Graham Berreen, Konstantinos Belogiannis, Alison R Hill, Muktar M Ibrahim, David W Cleary, Anish K Pandey, Holly E Humphries, Lauren Allen, Hans de Graaf, Martin C Maiden, Saul N Faust, Andrew R Gorringe and Robert C Read
Type: Article
| 2021
Distinct immune responses in patients infected with influenza or SARS-CoV-2, and in COVID-19 survivors, characterised by transcriptomic and cellular abundance differences in blood - Jelmer Legebeke, Jenny Lord, Rebekah Penrice-Randal, Andres F. Vallejo, Stephen Poole, Nathan J. Brendish, Xiaofeng Dong, Catherine Hartley, John W. Holloway, Jane S. Lucas, Anthony P. Williams, Gabrielle Wheway, Fabio Strazzeri, Aaron Gardner, James P.R. Schofield, Paul J. Skipp, Julian A. Hiscox, Marta E. Polak, Tristan W. Clark and Diana Baralle
Type: UNSPECIFIED
| 2021
| medRxiv
PTH-36 identification & service evaluation of a primary sclerosing cholangitis cohort using natural language processing - Robert Livingstone, Hang Phan, Florina Borca, Srishti Sarkar, Moeed Minto, Annie Dixey, Razzi Qaisar, Janisha Patel, Matthew Stammers and Markus Gwiggner
Type: Meeting abstract
| 2021
| Item not available on this server.
Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7 - Kordo Saeed
Type: Article
| 2021
| Item not available on this server.
Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial - Phillip D Monk, Richard J Marsden, Victoria J Tear, Jody Brookes, Toby N Batten, Marcin Mankowski, Felicity J Gabbay, Donna E Davies, Stephen T Holgate, Ling-Pei Ho, Tristan Clark, Ratko Djukanovic, Tom M A Wilkinson, Michael G Crooks, Davinder P S Dosanjh, Salman Siddiqui, Najib M Rahman, Jacklyn A Smith, Alexander Horsley, Timothy W Harrison, Dinesh Saralaya, Lorcan McGarvey, Alastair Watson, Edmund Foster, Adam Fleet, Dave Singh, Sophie Hemmings, Sandra Aitken, Sarah Dudley, Rona Beegan, Angela Thompson and Pedro M B Rodrigues
Type: Article
| 2021
Tissue-resident-like CD4
+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung - Paul Ogongo, Liku Bekele Tezera, Amanda Ardain, Shepherd Nhamoyebonde, Duran Ramsuran, Alveera Singh, Abigail Ng'oepe, Farina Karim, Taryn Naidoo, Khadija Khan, Kaylesh Dullabh, Michael Fehlings, Boon Heng Lee, Alessandra Nardin, Cecilia Lindestam Arlehamn, Alessandro Sette, Samuel Behar, Adrie Steyn, Rayhmun Madansein, Henrik Kløverpris, Paul Elkington and Alasdair Leslie
Type: Article
| 2021
| Item availability restricted.
Dupilumab-associated ocular surface disease: presentation, management and long-term sequelae - Magdalena Z Popiela, Ramez Barbara, Andrew M J Turnbull, Emma Corden, Beatriz Suarez Martinez-Falero, Daniel O'Driscoll, Michael R Ardern-Jones and Parwez N Hossain
Type: Article
| 2021
O69 outcome of direct access IBD physician delivered endoscopy for general practice referrals with suspected IBD - Sohail Rahmany, Matt Stammers, Louise Downey, Trevor Smith, Richard Felwick, Fraser Cummings and Markus Gwiggner
Type: Meeting abstract
| 2021
| Item not available on this server.
Ivermectin presents effective and selective antileishmanial activity in vitro and in vivo against Leishmania infantum and is therapeutic against visceral leishmaniasis - Thiago A R Reis, Joao A Oliveira-da-Silva, Grasiele S V Tavares, Debora V C Mendoca, Camila S Freitas, Rafaella R Costa, Daniela P Lage, Vivian T Martins, Amanda Sanchez Machado, Fernanda Fonseca Ramos, Alessandra M Silva, Fernanda Ludolf, Luciana M R Antinarelli, Rory C F Brito, Miguel A Chavez-Fumagalli, Maria Humbert, Bruno M. Roatt, Elaine S Coimbra and Eduardo Antonio Ferraz Coelho
Type: Article
| 2021
Spectrum, risk factors, and outcomes of neurological and psychiatric complications of COVID-19: a UK-wide cross-sectional surveillance study - Amy L Ross Russell, Marc Hardwick, Athavan Jeyanantham, Laura M White, Saumitro Deb, Girvan Burnside, Harriet Joy, Craig J Smith, Thomas A Pollak, Timothy R Nicholson, Nicholas WS Davies, Hadi Manji, Ava Easton, Stephen Ray, Michael S Zandi, Jonathan P. Coles, David K. Menon, Aravinthan Varatharaj, Beth Mccausland, Mark A Ellul, Naomi Thomas, Gerome Breen, Stephen Keddie, Michael P Lunn, John PS Burn, Graziella Quattrocchi, Luke Dixon, Claire M Rice, George Pengas, Rustam Al-Shahi Salman, Alan Carson, Eileen M. Joyce, Martin R Turner, Laura A Benjamin, Tom Solomon, Rachel Kneen, Sarah Pett, Rhys H Thomas, Benedict D Michael and Ian Galea
Type: Article
| 2021
Type: Dataset
| 2021
| University of Southampton
Type: Dataset
| 2021
| University of Southampton
PTH-32 development of a novel electronic referral grading & triage system - Srishti Sarkar, Robert Livingstone, Florina Borca, Matthew Stammers and Markus Gwiggner
Type: Meeting abstract
| 2021
| Item not available on this server.
Beyond visual acuity: development of a simple test of the slow-to-see phenomenon in children with infantile nystagmus syndrome - James Self, Helena Lee, Daniel Osborne, Megan J.E. Evans, Matt Dunn and M. Theodorou
Type: Article
| 2021
The α-dystrobrevins play a key role in maintaining the structure and function of the extracellular matrix-significance for protein elimination failure arteriopathies - Matthew MacGregor Sharp, Jordan Cassidy, Thomas Thornton, James Lyles, Abby Keable, Maureen Gatherer, Masato Yasui, Yoichiro Abe, Shinsuke Shibata, Roy O Weller, Dariusz C Górecki and Roxana O Carare
Type: Article
| 2021
Improving identification and brief advice for alcohol in hospital patients:: a new sustainable model using medicine management technicians - Julia Sinclair, Emily Walmsley, Lindsay Steel, Anya Farmbrough, Emily Smith and Jacqueline Swabe
Type: Article
| 2021
1 year posterior corneal changes after Bowman Layer Transplant for keratoconus. - Abdo Karim Tourkmani, Conor Lyons, Parwez Hossain, Aristides Konstantopoulos, David F. Anderson and Jorge Alio
Type: Article
| 2021
Type: Dataset
| 2021
| University of Southampton
Ocular manifestations of emerging viral diseases - Ashwin Venkatesh, Ravi Patel, Simran Goyal, Timothy Rajaratnam, Anant Sharma and Parwez Hossain
Type: Review
| 2021
Type: Dataset
| 2021
| University of Southampton
Whole genome sequencing in the diagnosis of primary ciliary dyskinesia - Gabrielle Wheway, N. Simon Thomas, Mary Carroll, Janice Coles, Regan Doherty, Patricia Goggin, Ben Green, Amanda Harris, David Hunt, Claire Jackson, Jenny Lord, Vito Mennella, James Thompson, Woolf Walker and Jane Lucas
Type: Article
| 2021
| Item availability restricted.
New NICE guidance on acne vulgaris: implications for first-line management in primary care - Jane Wilcock, Laura Kuznetsov, Jane Ravenscroft, Mohammed Irfan Rafiq and Eugene Healy
Type: Letter
| 2021
| Item not available on this server.
Type: Article
| 2021
Bidirectional epithelial-mesenchymal crosstalk provides self-sustaining profibrotic signals in pulmonary fibrosis - Liudi Yao, Yilu Zhou, Juanjuan Li, Leanne Wickens, Franco Conforti, Anna Simron Rattu, Fathima M Ibrahim, Aiman Alzetani, Benjamin Marshall, Sophie Fletcher, David Hancock, Timothy Wallis, Julian Downward, Robert Ewing, Luca Richeldi, Paul Skipp, Donna Davies, Mark Glynne Jones and Yihua Wang
Type: Article
| 2021