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Items where Division is "Current Faculties > Faculty of Medicine > Clinical and Experimental Sciences > Infection
Clinical and Experimental Sciences > Infection" and Year is 2022

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Number of items: 67.

NTHi-IAV coinfection of macrophages alters infection outcomes and inflammatory responses - Jodie Ackland, Ashley Heinson, David Cleary, Myron Christodoulides, Tom M.A. Wilkinson and Karl Staples
Type: Meeting abstract | 2022 | Item not available on this server.

Review of the femtosecond laser in DALK surgery - Joshua Adeyoju and Parwez Hossain
Type: Article | 2022 | Item not available on this server.

Public attitudes to a human challenge study with SARS-CoV-2: a mixed-methods study - Caroline Barker, Katharine Collet, Diane Gbesemete, Maria Piggin, Daniella Watson, Philippa Pristerà, Wendy Lawrence, Emma Smith, Michael Bahrami-Hessari, Halle Johnson, Katherine Baker, Ambar Qavi, Carmel McGrath, Christopher Chiu, Robert C Read and Helen Ward
Type: Article | 2022

The assessment of future RSV immunizations: How to protect all infants? - Louis Bont, Catherine Weil Olivier, Egbert Herting, Susanna Esposito, Jose Antonio Navarro Alonso, Federico Lega, Silke Mader, Ichiro Morioka, Kunling Shen, George A. Syrogiannopoulos, Saul N. Faust and Elena Bozzola
Type: Article | 2022

Combined RT-PCR and host response point-of-care testing in patients hospitalised with suspected COVID-19: a prospective diagnostic accuracy study - Nathan Brendish, Alex Tanner, Stephen Poole, Kate Beard, Vasanth Naidu, Christopher Mansbridge, Nicholas Norton, Helen Wheeler, Laura Presland and Tristan Clark
Type: Article | 2022

Immunocompromised children and young people are at no increased risk of severe COVID-19 - H. Chappell, R. Patel, C. Driessens, A.W. Tarr, W.l. Irving, P.J. Tighe, H.J. Jackson, T. Harvey-cowlishaw, L. Mills, M. Shaunak, D. Gbesemete, A. Leahy, J.S. Lucas, S.N. Faust and H. De Graaf
Type: Article | 2022

An in silico reverse vaccinology study of Brachyspira pilosicoli, the causative organism of intestinal spirochaetosis, to identify putative vaccine candidates - Myron Christodoulides, Daysiane De oliveira, David W. Cleary, Maria victoria Humbert, Ricardo a. Machado-De-Ávila and Roberto m. La ragione
Type: Article | 2022

Type: Monograph | 2022 | University Hospital Southampton NHS Foundation Trust

Is the UK prepared for seasonal influenza in 2022–23 and beyond? - Tristan Clark, Joshua Nazareth, Daniel Pan, Christopher Martin, Ian Burr, Sheena Sullivan, Iain Stephenson, Laura Nellums, Amandeep Sahota, Julian Tang and Manish Pareek
Type: Letter | 2022 | Item availability restricted.

Rapid syndromic PCR testing in patients with respiratory tract infections reduces time to results and improves microbial yield - Tristan Clark, S Serigstat, D Markussen, Harleen Grewal, M Ebbesen, O Kommedal, L Heggelund, CH van Werkhoven, D Faurholt-Jepsen, C Ritz, E Ulvestad, R Bjorneklett and ST Knoop
Type: Article | 2022

Changes in serotype prevalence of Streptococcus pneumoniae in Southampton, UK between 2006 and 2018 - David W. Cleary, Jessica Jones, Rebecca A. Gladstone, Karen L. Osman, Vanessa T. Devine, Johanna M Jefferies, Stephen D. Bentley, Saul N Faust and Stuart C. Clarke
Type: Article | 2022

Lactamica 7 Clinical Study Protocol V3.0, 04.10.2019: Defining the immune response to nasopharyngeal colonisation by the commensal Neisseria lactamica - Adam Dale, Anastasia, A Theodosiou, Diane, Frances Gbesemete, Jay Laver, Andrew Vaughan, Marta Polak, Paul Langford, Bidmos Fadil and Robert Read
Type: Monograph | 2022 | University of Southampton

Neisseria lactamica controlled human infection model - Adam P Dale, Diane F Gbesemete, Robert C Read and Jay R Laver
Type: Book Section | 2022 | Humana New York

Effect of colonisation with Neisseria lactamica on cross-reactive anti-meningococcal B-cell responses: a randomised, controlled, human infection trial - Adam P Dale, Anastasia A Theodosiou, Diane F Gbesemete, Jonathan M Guy, Eleanor F Jones, Alison R Hill, Muktar M Ibrahim, Hans de Graaf, Muhammad Ahmed, Saul N Faust, Andrew R Gorringe, Marta E Polak, Jay R Laver and Robert C Read
Type: Article | 2022 | Item not available on this server.

Whole genome sequencing of Acinetobacter baumannii clinical isolates from Terengganu, Malaysia (2017 – 2018) revealed the predominance of the multidrug resistance ST2, GC2 lineage - N.S. Din, Farahiyah Mohd Rani, S. Ismail, N.I.A. Rahman, N. Othman, F.H. Abdullah, David Cleary, Stuart C. Clarke and C.C. Yeo
Type: Conference or Workshop Item | 2022 | Item not available on this server.

Parental concern for clinically vulnerable child during first 18 months of the COVID pandemic - Corine Driessens, Lynne Mills, David Culliford, Ravin Patel, Emma Lee, Diane Gbesemete, Harry Chappell, Meera Shaunak, Saul N. Faust and Hans De Graaf
Type: Article | 2022

Immunosuppressed children and young people, psychosocial wellbeing, and the COVID-19 pandemic: a prospective cohort study - Corine Driessens, Lynne Mills, Ravin Patel, David Culliford, Diane Gbesemete, Emma Lee, Meera Shaunak, Harry Chappell, Saul N. Faust and Hans Graaf
Type: UNSPECIFIED | 2022

Development of a multicellular in vitro model of the meningeal blood-CSF barrier to study Neisseria meningitidis infection - Leo M. Endres, Marvin Jungblut, Mustafa Divyapicigil, Markus Sauer, Christian Stigloher, Myron Christodoulides, Brandon J. Kim and Alexandra Schubert-unkmeir
Type: Article | 2022

Type: Article | 2022

Type: Monograph | 2022 | University of Southampton

Efficacy, safety, and immunogenicity of a booster regimen of Ad26.COV2.S vaccine against COVID-19 (ENSEMBLE2): results of a randomised, double-blind, placebo-controlled, phase 3 trial - Karin Hardt, An Vandebosch, Jerald Sadoff, Mathieu Le Gars, Carla Truyers, David Lowson, Ilse Van Dromme, Johan Vingerhoets, Tobias Kamphuis, Gert Scheper, Javier Ruiz-Guiñazú, Saul N Faust, Christoph D Spinner, Hanneke Schuitemaker, Johan Van Hoof, Macaya Douoguih and Frank Struyf
Type: Article | 2022

Positive strand RNA viruses differ in the constraints they place on the folding of their negative strand - Morgan R. Herod, Joseph C. Ward, Andrew Tupin, Mark Harris, Nicola J. Stonehouse and Christopher J. Mccormick
Type: Article | 2022

Type: Article | 2022

Type: Conference or Workshop Item | 2022 | Item not available on this server.

Type: Conference or Workshop Item | 2022 | Item not available on this server.

A SARS-CoV-2 nucleocapsid ELISA represents a low-cost alternative to lateral flow testing for community screening in LMI countries - Maria Humbert, Precious Opurum, Nathan Brendish, Stephen Poole, Peijun He, Ioannis Katis, Jerry Quaye, Yaw Bediako, Patrick Duriez, R.W. Eason, Collin Sones, Osbourne Quaye, Gordon Awandare, Myron Christodoulides, Tristan Clark, Peter Quashie and Christopher Mccormick
Type: Article | 2022

Body Mass Index and clinical outcome of severe COVID-19 patients with acute hypoxic respiratory failure: unravelling the “obesity paradox” phenomenon - Michael Jennings, Maria Burova, Laura G. Hamilton, Elsie Hunter, Clare Mordena, Ryan Beecham, Darshni Pandya, Helen Moyses, Kordo Saeed, Paul Afolabi, Philip Calder and Ahilanandan Dushianthan
Type: Article | 2022

Type: Article | 2022

Type: Article | 2022

Type: Conference or Workshop Item | 2022 | Item not available on this server.

Recombinant guanosine-5′-triphosphate (GTP)-binding protein associated with Poloxamer 407-based polymeric micelles protects against Leishmania infantum infection - Daniela P. Lage, Amanda S. Machado, Danniele L. Vale, Camila S. Freitas, Flávia P. Linhares, Jamille M.O. Cardoso, Isabela A.G. Pereira, Fernanda F. Ramos, Grasiele S.V. Tavares, Fernanda Ludolf, João A. Oliveira-da-Silva, Raquel S. Bandeira, Alessandra M. Silva, Luciana C. Simões, Thiago A.R. Reis, Jamil S. Oliveira, Myron Christodoulides, Miguel A. Chávez-Fumagalli, Bruno M. Roatt, Vívian T. Martins and Eduardo A.F. Coelho
Type: Article | 2022 | Item availability restricted.

Safety and immunogenicity of the inactivated whole-virus adjuvanted COVID-19 vaccine VLA2001 - Rajeka Lazarus, Christian Taucher, Claire Brown, Irena Corbic, Leon Danon and Katrin Dubischar
Type: Article | 2022

Evaluating the immune response in treatment-naïve hospitalised patients with influenza and COVID-19 - Jelmer Legebeke, Jenny Lord, Rebekah Penrice-Randal, Andres F Vallejo, Stephen Poole, Nathan Brendish, Xiaofeng Dong, Catherine Hartley, John Holloway, Jane Lucas, Anthony Williams, Gabrielle Wheway, Fabio Strazzeri, Aaron Gardner, James P R Schofield, Paul Skipp, Julian A. Hiscox, Marta Polak, Tristan Clark and Diana Baralle
Type: Article | 2022

Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine in children aged 6-17 years: a preliminary report of COV006, a phase 2 single-blind, randomised, controlled trial - Grace Li, Federica Cappuccini, Natalie G Marchevsky, Parvinder K Aley, Robert Aley, Rachel Anslow, Xinxue Liu, Teresa Lambe and Andrew J Pollard
Type: Article | 2022

Immune responses to SARS-CoV-2 variants after two and three doses of vaccine in B-cell malignancies: UK PROSECO Study - Sean H. Lim, Beth Stuart, Debora Joseph-Pietras, Marina Johnson, Nicola Campbell, Adam Kelly, Danielle Jeffrey, Anna H Turaj, Kate Rolfvondenbaumen, Celine Galloway, Thomas Wynn, Adam R. Coleman, Benjamin Ward, Karen Long, Helen Coleman, Carina Mundy, Andrew T. Bates, Diana Ayres, Robert Lown, Janlyn Falconer, Oliver Brake, James Batchelor, Victoria Willimott, Anna Bowzyk Al-Naeeb, Lisa Robinson, Ann O'Callaghan, Graham P Collins, Tobias Menne, Saul N Faust, Christopher P Fox, Matthew Ahearne, Peter W M Johnson, Andrew J Davies and David Goldblatt
Type: Article | 2022

Antibiotics for lower respiratory tract infection in children presenting in primary care (ARTIC-PC): the predictive value of molecular testing - Paul Little, Robert C. Read, Taeko Becque, Nick A. Francis, Alastair D. Hay, Beth Stuart, Gilly O'Reilly, Natalie Thompson, Kerenza Hood, Saul Faust, Kay Wang, Michael Moore and Theo Verheij
Type: Article | 2022

Persistence of immunogenicity after seven COVID-19 vaccines given as third dose boosters following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK: three month analyses of the COV-BOOST trial - Xinxue Liu, Alasdair P S Munro, Shuo Feng, Leila Janani, Parvinder K Aley, Gavin Babbage, Katrina Cathie, Daniel R Owens, Robert C Read and Saul N Faust
Type: Article | 2022

Routine molecular point-of-care testing for SARS-CoV-2 reduces hospital-acquired COVID-19 - Robert Livingstone, Hlaing Lin, Nathan Brendish, Stephen Poole, Florina Borca, Alex Tanner, Trevor Smith, Matt Stammers and Tristan Clark
Type: Article | 2022

Emergence of a multidrug-resistant and virulent Streptococcus pneumoniae lineage mediates serotype replacement after PCV13: an international whole-genome sequencing study - Stephanie W. Lo, Kate Mellor, Robert Cohen, Alba Redin Alonso, Sophie Belman, Narender Kumar, Paulina A. Hawkins, Rebecca Gladstone, Anne von Gottberg, Balaji Veeraraghavan, K.L. Ravikumar, Rama Kandasamy, Andrew J. Pollard, Samir K. Saha, Godfrey Bigogo, Martin Antonio, Brenda Kwambana-Adams, Shaper Mirza, Sadia Shakoor, Imran Nisar, Jennifer E. Cornick, Deborah Lehmann, Rebecca L. Ford, Betuel Sigauque, Paul Turner, Jennifer Moïsi, Stephen K. Obaro, Ron Dagan, Idrissa Diawara, Anna Skoczyńska, Hui Wang, Philip E. Carter, Keith P. Klugman, Gail Rodgers, Robert F. Breiman, Lesley McGee, Stephen D Bentley, Carmen Muñoz-Almagro, Emmanuelle Varon and Stuart C. Clarke
Type: Article | 2022

Detecting anti–SARS-CoV-2 antibodies in urine samples: a noninvasive and sensitive way to assay COVID-19 immune conversion - Fernanda Ludolf, Fernanda F. Ramos, Flávia F. Bagno, João A. Oliveira-Da-Silva, Thiago A.R. Reis, Myron Christodoulides, Paula F. Vassallo, Cecilia G. Ravetti, Vandack Nobre, Flavio G. da Fonseca and Eduardo A.F. Coelho
Type: Article | 2022 | Item not available on this server.

Leishmania LiHyC protein is immunogenic and induces protection against visceral leishmaniasis - Amanda S. Machado, Daniela P. Lage, Danniele L. Vale, Camila S. Freitas, Flávia P. Linhares, Jamille M.O. Cardoso, João A. Oliveira-da-Silva, Isabela A.G. Pereira, Fernanda F. Ramos, Grasiele S.V. Tavares, Fernanda Ludolf, Raquel S. Bandeira, Luiz G.N. Maia, Daniel Menezes-Souza, Mariana C. Duarte, Miguel A. Chávez-Fumagalli, Bruno M. Roatt, Myron Christodoulides, Vívian T. Martins and Eduardo Antonio Ferraz Coelho
Type: Article | 2022 | Item not available on this server.

Impact of bacterial strain acquisition in the lung of patients with COPD: the AERIS study - Lucio Malvisi, Aparna Yarraguntla, Marie-Cecile Mortier, Karen L Osman, David Cleary, Beatrice Sente, Thierry G. Pascal, Vincent Weynants, Stuart Clarke, Laura Taddei, Tom M.A. Wilkinson, Jeanne-Marie Devaster, Nathalie Devos and Stephen Wootton
Type: Article | 2022

FebriDx host response point-of-care testing improves patient triage for coronavirus disease 2019 (COVID-19) in the emergency department - Christopher Mansbridge, Alex Tanner, Kate Beard, Florina Borca, Hang Thi Thu Phan, Nathan Brendish, Stephen Poole, Christopher Hill, Michael Kuber, Robert Crouch, Waddington Daniel and Tristan Clark
Type: Article | 2022

Compassionate use of Pulmonary Vasodilators in Acute Severe Hypoxic Respiratory Failure due to COVID-19 - Lewis Matthews, Laurence Baker, Matteo Ferrari, Weronika Sanchez, John Pappachan, Mike Pw Grocott, Ahilanandan Dushianthan, Thomas Wilkinson, Hannah Burke, Anna Freeman, Michael Celinski, Saul Faust, Gareth Thomas and Christopher Kipps
Type: Article | 2022

Respiratory virus transmission using a novel viral challenge model: An observational cohort study - Marie-Jo Medina, Joshua Nazareth, Helen Dillon, Christopher Wighton, Srini Bandi, Daniel Pan, Karl Nicholson, Tristan Clark, Peter Andrews and Manish Pareek
Type: Article | 2022

Flau-A, a naphthoquinone derivative, is a promising therapeutic candidate against visceral leishmaniasis: A preliminary study - Débora V.C. Mendonça, Grasiele S.V. Tavares, Isabela A.G. Pereira, João A Oliveira-da-Silva, Fernanda F. Ramos, Daniela P. Lage, Amanda S. Machado, Lívia M. Carvalho, Thiago A.R. Reis, Ana Maria R.S. Carvalho, Flaviano M. Ottoni, Fernanda Ludolf, Camila S. Freitas, Vívian T. Martins, Miguel A. Chávez-Fumagalli, Mariana C. Duarte, Maria V. Humbert, Bruno M. Roatt, Daniel Menezes-Souza, Ricardo J. Alves and Eduardo A.F. Coelho
Type: Article | 2022

Whole genome sequence analysis of two Acinetobacter oleivorans clinical isolates from Terengganu, Malaysia, revealed the carriage of several virulence factors - Farahiyah Mohd Rani, N.I.A. Rahman, S. Ismail, N. Othman, David Cleary, F.H. Abdullah, Stuart C. Clarke and C.C. Yeo
Type: Conference or Workshop Item | 2022

Draft genome sequences of two Acinetobacter soli clinical isolates from a tertiary hospital in Terengganu, Malaysia - Farahiyah Mohd Rani, Nor Iza A. Rahman, Salwani Ismail, David Cleary, Stuart Clarke and Chew Chieng Yeo
Type: Article | 2022

The characterization of Moraxella catarrhalis carried in the general population - Denise E. Morris, Karen L. Osman, David W. Cleary and Stuart C. Clarke
Type: Article | 2022

Type: Article | 2022

Blood gene expression predicts intensive care unit admission in hospitalised patients with COVID-19 - Rebekah Penrice-Randal, Xiaofeng Dong, Andrew George Shapanis, Aaron Gardner, Nicholas Harding, Jelmer Legebeke, Jenny Lord, Andres F Vallejo, Stephen Poole, Nathan J Brendish, Catherine Hartley, Anthony P Williams, Gabrielle Wheway, Marta E Polak, Fabio Strazzeri, James P R Schofield, Paul J Skipp, Julian A Hiscox, Tristan W Clark and Diana Baralle
Type: Article | 2022

Safety and immunogenicity of a self-amplifying RNA vaccine against COVID-19: COVAC1, a phase I, dose-ranging trial - Katrina M Pollock, Hannah M Cheeseman, Alexander J Szubert, Vincenzo Libri, Marta Boffito and David Owen
Type: Article | 2022

Community seroprevalence of SARS-CoV-2 in children and adolescents in England, 2019-2021 - Helen Ratcliffe, K.S. Tiley, Nick Andrews, Gayatri Amirthalingam, I. Vichos, E. Morey, N.L. Douglas, S. Marinou, Emma Plested, Parvinder Aley, Eva P. Galiza, Saul N. Faust, S. Hughes, Clare S. Murray, Marion Roderick, Fiona Shackley, Sam J. Oddie, Tim Lees, D.P.J. Turner, M. Raman, Stephen Owens, Paul Turner, H. Cockerill, J. Lopez Bernal, E. Linley, Ray Borrow, Kevin Brown, Mary Elizabeth Ramsay, M. Voysey and Matthew D. Snape
Type: Article | 2022

A systematic review and meta-analysis of the prevalence of human cytomegalovirus shedding in seropositive pregnant women - Shari Sapuan, Anastasia Theodosiou, Blair L. Strang, Paul T. Heath and Christine E. Jones
Type: Review | 2022

Type: Article | 2022

Type: Article | 2022

Type: Article | 2022

Type: Article | 2022

Phase 1/2a Safety and Immunogenicity of an Adenovirus 26 Vector Respiratory Syncytial Virus (RSV) Vaccine Encoding Prefusion F in Adults 18–50 Years and RSV-Seropositive Children 12–24 Months - Arabella S.V. Stuart, Miia Virta, Kristi Williams, Ilkka Seppa, Robyn Hartvickson, Melanie Greenland, Edmund Omoruyi, Arangassery Rosemary Bastian, Wouter Haazen, Nadine Salisch, Efi Gymnopoulou, Benoit Callendret, Saul N Faust, Matthew D Snape and Esther Heijnen
Type: Article | 2022

Comparison of UK paediatric SARS-CoV-2 admissions across the first and second pandemic waves - Olivia V. Swann, Louisa Pollock, Karl A. Holden, Alasdair P.S. Munro, Aisleen Bennett, Thomas C. Williams and Malcolm G. Semple
Type: Article | 2022

Blink reflex in neurotrophic keratopathy: An electrophysiological evaluation - Sara Fatima Syed, Andrew Marshall, Parwez Hossain and Saghir Ahmed Sadiq
Type: Article | 2022

Lactamica 9: Clinical study protocol. Defining upper respiratory colonisation and microbiome evolution in mother-infant pairs following Neisseria lactamica inoculation in late pregnancy - Anastasia Theodosiou, Christine E. Jones, Robert Read, David Cleary, Jay Laver, Adam Dale, Matthew Coleman and Debby Bogaert
Type: Other | 2022

Type: Article | 2022

Safety, immunogenicity, and efficacy of a COVID-19 vaccine (NVX-CoV2373) co-administered with seasonal influenza vaccines: an exploratory substudy of a randomised, observer-blinded, placebo-controlled, phase 3 trial - Seth Toback, Eva Galiza, Catherine Cosgrove, James Galloway, Anna L. Goodman, Pauline A. Swift, Sankarasubramanian Rajaram, Alison Graves-Jones, Jonathan Edelman, Fiona Burns, Angela M. Minassian, Iksung Cho, Lakshmi Kumar, Joyce S. Plested, E. Joy Rivers, Andreana Robertson, Filip Dubovsky, Greg Glenn and Paul T. Heath
Type: Article | 2022

Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial - Cherry-Ann Waldron, Emma Thomas-Jones, Jolanta Bernatoniene, Lucy Brookes-Howell, Saul N Faust, Debbie Harris, Lucy Hinds, Kerenza Hood, Chao Huang, Céu Mateus, Philip Pallmann, Sanjay Patel, Stéphane Paulus, Matthew Peak, Colin Powell, Jennifer Preston and Enitan D Carrol
Type: Article | 2022

Multi-excitation Raman spectroscopy for label-free, strain-level characterization of bacterial pathogens in artificial sputum media - Jeremy Webb, Adam Lister, Callum Highmore, Niall Hanrahan, James, Arthur Read, Alasdair, Peter Stuart Munro, Samuel Tan, Raymond Allan, Saul Faust and Sumeet Mahajan
Type: Article | 2022

Type: Article | 2022

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